Laborator Medical Modern - ALFA diagnostica

{"component":"cHomeMagazineContainer","data":{"goto":"id_magazine_home_infoblock","objects":[{"id":"469","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1647338400","views":null,"showonhome":"0","magazinetype":"2","name":"Diagnosticul precoce a CANCERULUI MAMAR cu ajutorul Inetigen\u021bei Artificiale!","author":"author blog meta","info":null,"title":"Diagnosticul precoce a CANCERULUI MAMAR cu ajutorul Inetigen\u021bei Artificiale!","urlsuffix":null,"description":"<div>Pentru a \u00eenvinge cancerul mamar, acesta trebuie depistat la timp. \u0218i cel mai important \u2013 este de a ac\u021biona preventiv! Adic\u0103, fiecare femeie trebuie s\u0103 depun\u0103 efortul necesar pentru a g\u0103si timpul \u0219i posibilitatea, nu numai de a efectua o examinare, ci \u0219i pentru a consulta un medic mamolog-oncolog.\u00a0\u00a0 \r\n\u00centrebarea este \u2013 ce fel de examinare? \r\n\u00a0<\/div>\r\n\r\n<div>\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0<\/span>Mamografia sau examinarea ecografic\u0103 a glandelor mamare\u00a0 \r\n\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0DIFEREN\u021aA EXIST\u0102 \r\n\u00a0<\/div>\r\n\r\n<div>\u00a0<\/div>\r\n\r\n<div>Mamografia contribuie la depistarea precoce a cancerului mamar, dar nu la toate femeile! \r\nDe ce? \r\n \r\n\u00cen primul r\u00e2nd, aproximativ la fiecare a doua femeie (adesea mai tinere) \u021besutul glandei mamare este, din punct de vedere fiziologic, mai dens, \u0219i acesta este motivul principal din cauza c\u0103ruia mamografia poate \u201erata sau omite\u201d cancerul mamar! \r\n\u00cen al doilea r\u00e2nd, la depistarea unei forma\u021biuni de volum suspecte, cu scopul de a \u201enu omite\u201d cancerul mamar, medicii \u00een majoritatea cazurilor recomand\u0103 efectuarea biopsiei mamare \u2013 unei proceduri invazive \u0219i traumatizante din punct de vedere psihologic, ale c\u0103rei rezultate, \u00een 80% de cazuri, NU confirm\u0103 prezen\u021ba cancerului mamar! \r\n\u00a0 \r\nExaminarea ecografic\u0103 este lipsit\u0103 de neajunsurile mamografiei \u0219i, fiind inofensiv\u0103, reprezint\u0103 metoda de preferin\u021b\u0103. Dar din p\u0103cate, anumite erori pot fi prezente \u0219i \u00een acest caz \u2013 analizarea imaginii ecografice este, prin defini\u021bie, un proces subiectiv, legat de calificarea \u0219i experien\u021ba medicului specialist, capacit\u0103\u021bile tehnice ale ecografului etc. \r\n \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 Smart Ultrasound \r\n\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Tehnologia revolu\u021bionar\u0103 de la KOIOS MEDICAL \r\n\u00a0 \r\nKOIOS MEDICAL \u2013 prima \u0219i unica din lume companie american\u0103, care a elaborat \u0219i a implementat \u00een examinarea ecografic\u0103 a cancerului mamar tehnologia Smart Ultrasound, ce permite medicului ecografist s\u0103 ob\u021bin\u0103 o alt\u0103 \u201ea doua opinie\u201d de la Inteligen\u021ba Artificial\u0103 (IA) \u00een doar 2 secunde! \r\nRezultatele implement\u0103rii acestei noi tehnologii, conform datelor clinicilor din SUA, impresioneaz\u0103: acurate\u021bea diagnostic\u0103rii cancerului mamar a crescut p\u00e2n\u0103 la 98%! Iar num\u0103rul biopsiilor inutile, \u201ebenigne\u201d, a sc\u0103zut cu 55%! \r\n \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 Smart Ultrasound \r\n\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0la ALFAMED \r\n\u00a0 \r\nTehnologia de ultima genera\u021bie Smart Ultrasound a fost implementat\u0103 cu succes \u00een clinica ALFAMED (subdiviziunea ALFA diagnostica) \u00een a doua jum\u0103tate a anului 2021. \u00cen practic\u0103, procesul examin\u0103rii este urm\u0103torul: dac\u0103 \u00een timpul efectu\u0103rii ecografiei mamare, medicul depisteaz\u0103 o forma\u021biune de volum suspect\u0103, atunci analizarea \u0219i interpretarea imaginii ecografice este efectuat\u0103 de IA, care momentan clasific\u0103 forma\u021biunea depistat\u0103 conform scalei BI-RADS, bine-cunoscute medicilor mamologi-oncologi. Dup\u0103 efectuarea examin\u0103rii, medicul mamolog-oncolog consult\u0103 \u0219i examineaz\u0103 pacienta \u0219i, \u00een combina\u021bie cu datele BI-RADS, ia o decizie justificat\u0103 de a recomanda efectuarea biopsiei mamare sau de a continua monitorizarea clinic\u0103. \r\n \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 Smart Ultrasound \r\n\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0CERTIFICARE \r\n\u00a0 \r\nTehnologia de analizare \u0219i interpretare a imaginilor ecografice Smart Ultrasound este aprobat\u0103 pentru diagnosticare \u00een SUA, \u021b\u0103rile UE \u0219i, de asemenea, \u00eenregistrat\u0103 \u00een Moldova (FDA, CE, AMED, IVD). \r\n\u00a0 \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 ALEGEREA V\u0102 APAR\u021aINE \r\n\u00a0 \r\n\u00cen cele din urm\u0103, alegerea final\u0103 a metodei de diagnosticare este privilegiul pacientei. La r\u00e2ndul s\u0103u, sarcina noastr\u0103 este de a informa despre noile realiz\u0103ri, ce contribuie la \u00eembun\u0103t\u0103\u021birea calit\u0103\u021bii de diagnosticare \u0219i, prin urmare, la victoria asupra bolii, ca urmare a c\u0103rei anual decedeaz\u0103 peste 1200 de femei din \u021bar\u0103. \r\n \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 DETALII SUPLIMENTARE<\/div>\r\n\r\n<div> \r\nServiciul\r\n<div>\u00a0<\/div>\r\n\r\n<div>\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0<\/span>Examinarea ecografic\u0103 a glandelor mamare cu interpretarea forma\u021biunilor de volum suspecte, utiliz\u00e2nd Inteligen\u021ba Artificial\u0103 conform clasific\u0103rii BI-RADS.<\/div>\r\n \r\nMedic ecografist \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0<\/span>Hristeva Lilia, medic categorie superioar\u0103 \r\n \r\nCostul \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0<\/span>750 lei \r\n \r\nProgramare \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0<\/span>(022) 90 88 00 \r\n \r\nAdres\u0103 \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0<\/span>str. Bucure\u0219ti, 116 \r\n \r\nSite \r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0<\/span><a href=\"https:\/\/alfamed.md\/?doctors=hristeva-lilia&fbclid=IwAR1PaJtzTTw8yI-K4NsXz-stpOt0d4YQ_qjw1FTcHuBvHgSBAD9bnT5SII4\">www.alfamed.md<\/span><\/a><\/div>\r\n\r\n<div>\u00a0<\/div>","description_clear":"Pentru a \u00eenvinge cancerul mamar, acesta trebuie depistat la timp. \u0218i cel mai important \u2013 este de a ac\u021biona preventiv! Adic\u0103, fiecare femeie trebuie s\u0103 depun\u0103 efortul necesar pentru a g\u0103si timpul \u0219i posibilitatea, nu numai de a efectua o examinare, ci \u0219i pentru a consulta un medic mamolog-oncolog.\u00a0\u00a0\r\n\u00centrebarea este \u2013 ce fel de examinare?\r\n\u00a0\r\n\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0Mamografia sau examinarea ecografic\u0103 a glandelor mamare\u00a0\r\n\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0DIFEREN\u021aA EXIST\u0102\r\n\u00a0\r\n\r\n\u00a0\r\n\r\nMamografia contribuie la depistarea precoce a cancerului mamar, dar nu la toate femeile!\r\nDe ce?\r\n\r\n\u00cen primul r\u00e2nd, aproximativ la fiecare a doua femeie (adesea mai tinere) \u021besutul glandei mamare este, din punct de vedere fiziologic, mai dens, \u0219i acesta este motivul principal din cauza c\u0103ruia mamografia poate \u201erata sau omite\u201d cancerul mamar!\r\n\u00cen al doilea r\u00e2nd, la depistarea unei forma\u021biuni de volum suspecte, cu scopul de a \u201enu omite\u201d cancerul mamar, medicii \u00een majoritatea cazurilor recomand\u0103 efectuarea biopsiei mamare \u2013 unei proceduri invazive \u0219i traumatizante din punct de vedere psihologic, ale c\u0103rei rezultate, \u00een 80% de cazuri, NU confirm\u0103 prezen\u021ba cancerului mamar!\r\n\u00a0\r\nExaminarea ecografic\u0103 este lipsit\u0103 de neajunsurile mamografiei \u0219i, fiind inofensiv\u0103, reprezint\u0103 metoda de preferin\u021b\u0103. Dar din p\u0103cate, anumite erori pot fi prezente \u0219i \u00een acest caz \u2013 analizarea imaginii ecografice este, prin defini\u021bie, un proces subiectiv, legat de calificarea \u0219i experien\u021ba medicului specialist, capacit\u0103\u021bile tehnice ale ecografului etc.\r\n\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 Smart Ultrasound\r\n\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Tehnologia revolu\u021bionar\u0103 de la KOIOS MEDICAL\r\n\u00a0\r\nKOIOS MEDICAL \u2013 prima \u0219i unica din lume companie american\u0103, care a elaborat \u0219i a implementat \u00een examinarea ecografic\u0103 a cancerului mamar tehnologia Smart Ultrasound, ce permite medicului ecografist s\u0103 ob\u021bin\u0103 o alt\u0103 \u201ea doua opinie\u201d de la Inteligen\u021ba Artificial\u0103 (IA) \u00een doar 2 secunde!\r\nRezultatele implement\u0103rii acestei noi tehnologii, conform datelor clinicilor din SUA, impresioneaz\u0103: acurate\u021bea diagnostic\u0103rii cancerului mamar a crescut p\u00e2n\u0103 la 98%! Iar num\u0103rul biopsiilor inutile, \u201ebenigne\u201d, a sc\u0103zut cu 55%!\r\n\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 Smart Ultrasound\r\n\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0la ALFAMED\r\n\u00a0\r\nTehnologia de ultima genera\u021bie Smart Ultrasound a fost implementat\u0103 cu succes \u00een clinica ALFAMED (subdiviziunea ALFA diagnostica) \u00een a doua jum\u0103tate a anului 2021. \u00cen practic\u0103, procesul examin\u0103rii este urm\u0103torul: dac\u0103 \u00een timpul efectu\u0103rii ecografiei mamare, medicul depisteaz\u0103 o forma\u021biune de volum suspect\u0103, atunci analizarea \u0219i interpretarea imaginii ecografice este efectuat\u0103 de IA, care momentan clasific\u0103 forma\u021biunea depistat\u0103 conform scalei BI-RADS, bine-cunoscute medicilor mamologi-oncologi. Dup\u0103 efectuarea examin\u0103rii, medicul mamolog-oncolog consult\u0103 \u0219i examineaz\u0103 pacienta \u0219i, \u00een combina\u021bie cu datele BI-RADS, ia o decizie justificat\u0103 de a recomanda efectuarea biopsiei mamare sau de a continua monitorizarea clinic\u0103.\r\n\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 Smart Ultrasound\r\n\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0CERTIFICARE\r\n\u00a0\r\nTehnologia de analizare \u0219i interpretare a imaginilor ecografice Smart Ultrasound este aprobat\u0103 pentru diagnosticare \u00een SUA, \u021b\u0103rile UE \u0219i, de asemenea, \u00eenregistrat\u0103 \u00een Moldova (FDA, CE, AMED, IVD).\r\n\u00a0\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 ALEGEREA V\u0102 APAR\u021aINE\r\n\u00a0\r\n\u00cen cele din urm\u0103, alegerea final\u0103 a metodei de diagnosticare este privilegiul pacientei. La r\u00e2ndul s\u0103u, sarcina noastr\u0103 este de a informa despre noile realiz\u0103ri, ce contribuie la \u00eembun\u0103t\u0103\u021birea calit\u0103\u021bii de diagnosticare \u0219i, prin urmare, la victoria asupra bolii, ca urmare a c\u0103rei anual decedeaz\u0103 peste 1200 de femei din \u021bar\u0103.\r\n\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0 DETALII SUPLIMENTARE\r\n\r\n\r\nServiciul\r\n\u00a0\r\n\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0Examinarea ecografic\u0103 a glandelor mamare cu interpretarea forma\u021biunilor de volum suspecte, utiliz\u00e2nd Inteligen\u021ba Artificial\u0103 conform clasific\u0103rii BI-RADS.\r\n\r\nMedic ecografist\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0Hristeva Lilia, medic categorie superioar\u0103\r\n\r\nCostul\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0750 lei\r\n\r\nProgramare\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0(022) 90 88 00\r\n\r\nAdres\u0103\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0str. Bucure\u0219ti, 116\r\n\r\nSite\r\n\u00a0 \u00a0 \u00a0 \u2713\u00a0\u00a0www.alfamed.md\r\n\r\n\u00a0","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/469\/1","url":"\/ro\/magazine\/diagnosticul-precoce-a-cancerului-mamar-cu-ajutorul-inetigentei-artificiale-469","url_full":"https:\/\/alfalab.md\/ro\/magazine\/diagnosticul-precoce-a-cancerului-mamar-cu-ajutorul-inetigentei-artificiale-469","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/diagnosticul-precoce-a-cancerului-mamar-cu-ajutorul-inetigentei-artificiale-469","show_startdate_d":"","show_enddate_d":"","date_d":"2022-03-15","show_startdate_text":"","show_enddate_text":"","date_text":"2022-03-15","date_day":"15","date_month":"Martie","date_published":"2022-03-15","date_modify":"2022-03-15","image_id":"8978","image_ids":["8978"],"image_url":"\/files\/getfile\/8978\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/8978\/","activegallery":[{"id":"270","parentclass":"magazine","idparentclass":"469","order":"1","idfile":"8978","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/8978\/","name":"Alfalab.png"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"468","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1646647200","views":null,"showonhome":"0","magazinetype":"2","name":"ALFA diagnostica: un test vital pentru cei care administreaz\u0103 clopidogrel (Plavix)","author":"author blog meta","info":null,"title":"ALFA diagnostica: un test vital pentru cei care administreaz\u0103 clopidogrel (Plavix)","urlsuffix":null,"description":"Laboratorul medical ALFA diagnostica a implementat cu succes un test farmacogenetic care ajut\u0103 cardiologii s\u0103 selecteze doze individuale de clopidogrel pentru pacien\u021bi, cresc\u00e2nd astfel semnificativ eficacitatea acestuia \u00een prevenirea trombozei.<\/em><\/strong> \r\n \r\nClopidogrel (Plavix), un medicament antiagregant esen\u021bial, este utilizat pe scar\u0103 larg\u0103 cu scopul principal de a preveni dezvoltarea trombozei, cea mai periculoas\u0103 complica\u021bie la pacien\u021bii cu infarct miocardic, accident vascular cerebral sau dup\u0103 stentarea coronarian\u0103. \r\n \r\nEsen\u021ba problemei<\/strong> \r\nLa fiecare al treilea pacient (!) medicamentul este ineficient, adic\u0103 riscul de tromboz\u0103 nu dispare. Cauza principal\u0103 sunt caracteristicile genetice individuale ale fiec\u0103rui pacient. \r\nDup\u0103 ce a intrat \u00een organism, clopidogrelul trebuie s\u0103 se transforme \u00eentr-un medicament activ. Dac\u0103, din cauza caracteristicilor genetice individuale, procesul de transformare este \u00eencetinit, atunci eficacitatea medicamentului este redus\u0103 semnificativ, ceea ce \u00eenseamn\u0103 c\u0103 riscul de tromboz\u0103 r\u0103m\u00e2ne. \r\n \r\nTest nou<\/strong> \r\nAnaliza genelor implicate \u00een acest proces poate dezv\u0103lui caracteristicile individuale ale metabolismului clopidogrelului, fapt care permite medicului curant s\u0103 recomande pacientului s\u0103 ia fie doze standard, fie crescute sau reduse de clopidogrel, fie s\u0103 utilizeze medicamente alternative. \r\n \r\nImportant<\/strong> \r\nPrescrierea testului, interpretarea rezultatelor, corectarea dozei sunt prerogativele medicului. \r\n \r\nDetalii<\/strong> \r\nMai multe despre pre\u021buri, termeni, preg\u0103tire pentru test, adresele Centrelor de prelevare din Chi\u0219in\u0103u \u0219i B\u0103l\u021bi \u0219i intervalul prelev\u0103rii testului g\u0103si\u021bi <a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/G\/genotipare-cyp2c19-avsv1-4405\">aici<\/a>. ","description_clear":"Laboratorul medical ALFA diagnostica a implementat cu succes un test farmacogenetic care ajut\u0103 cardiologii s\u0103 selecteze doze individuale de clopidogrel pentru pacien\u021bi, cresc\u00e2nd astfel semnificativ eficacitatea acestuia \u00een prevenirea trombozei.\r\n\r\nClopidogrel (Plavix), un medicament antiagregant esen\u021bial, este utilizat pe scar\u0103 larg\u0103 cu scopul principal de a preveni dezvoltarea trombozei, cea mai periculoas\u0103 complica\u021bie la pacien\u021bii cu infarct miocardic, accident vascular cerebral sau dup\u0103 stentarea coronarian\u0103.\r\n\r\nEsen\u021ba problemei\r\nLa fiecare al treilea pacient (!) medicamentul este ineficient, adic\u0103 riscul de tromboz\u0103 nu dispare. Cauza principal\u0103 sunt caracteristicile genetice individuale ale fiec\u0103rui pacient.\r\nDup\u0103 ce a intrat \u00een organism, clopidogrelul trebuie s\u0103 se transforme \u00eentr-un medicament activ. Dac\u0103, din cauza caracteristicilor genetice individuale, procesul de transformare este \u00eencetinit, atunci eficacitatea medicamentului este redus\u0103 semnificativ, ceea ce \u00eenseamn\u0103 c\u0103 riscul de tromboz\u0103 r\u0103m\u00e2ne.\r\n\r\nTest nou\r\nAnaliza genelor implicate \u00een acest proces poate dezv\u0103lui caracteristicile individuale ale metabolismului clopidogrelului, fapt care permite medicului curant s\u0103 recomande pacientului s\u0103 ia fie doze standard, fie crescute sau reduse de clopidogrel, fie s\u0103 utilizeze medicamente alternative.\r\n\r\nImportant\r\nPrescrierea testului, interpretarea rezultatelor, corectarea dozei sunt prerogativele medicului.\r\n\r\nDetalii\r\nMai multe despre pre\u021buri, termeni, preg\u0103tire pentru test, adresele Centrelor de prelevare din Chi\u0219in\u0103u \u0219i B\u0103l\u021bi \u0219i intervalul prelev\u0103rii testului g\u0103si\u021bi aici.","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/468\/1","url":"\/ro\/magazine\/alfa-diagnostica-un-test-vital-pentru-cei-care-administreaza-clopidogrel-plavix-468","url_full":"https:\/\/alfalab.md\/ro\/magazine\/alfa-diagnostica-un-test-vital-pentru-cei-care-administreaza-clopidogrel-plavix-468","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/alfa-diagnostica-un-test-vital-pentru-cei-care-administreaza-clopidogrel-plavix-468","show_startdate_d":"","show_enddate_d":"","date_d":"2022-03-07","show_startdate_text":"","show_enddate_text":"","date_text":"2022-03-07","date_day":"07","date_month":"Martie","date_published":"2022-03-07","date_modify":"2022-03-07","image_id":"8966","image_ids":["8966"],"image_url":"\/files\/getfile\/8966\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/8966\/","activegallery":[{"id":"269","parentclass":"magazine","idparentclass":"468","order":"1","idfile":"8966","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/8966\/","name":"435 x 286 px.png"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"461","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1639044000","views":null,"showonhome":"0","magazinetype":"2","name":"ALFA diagnostica: 5 ani de activitate de succes!","author":"author blog meta","info":null,"title":"Alfa Diagnostica: 5 ani de activitate de succes!","urlsuffix":null,"description":"\u00cen data de 9 decembrie 2016, ALFA diagnostica \u0219i-a deschis u\u0219ile pentru primii s\u0103i pacien\u021bi, care au efectuat analize aici pentru prima dat\u0103. P\u00e2n\u0103 \u00een prezent, num\u0103rul pacien\u021bilor examina\u021bi s-a apropiat deja de 500.000, iar num\u0103rul analizelor efectuate a dep\u0103\u0219it 2 500 000!<\/span> \r\n\u00a0<\/span> \r\nCalitate<\/strong> \r\n\u00a0<\/span> \r\n\u00cen diagnosticul de laborator, calitatea este o valoare special\u0103, care include at\u00e2t acurate\u021bea \u0219i fiabilitatea, c\u00e2t \u0219i beneficiul clinic. \u00cenc\u0103 de la \u00eenfiin\u021bare, principalele eforturi ale companiei au fost \u00eendreptate c\u0103tre asigurarea calit\u0103\u021bii corespunz\u0103toare \u2013 formarea continu\u0103 a personalului, noi analizoare, tehnologii, \u00eembun\u0103t\u0103\u021birea sistemului de control al calit\u0103\u021bii, analiza constant\u0103 \u0219i eliminarea oric\u0103ror obstacole care afecteaz\u0103 calitatea.<\/span> \r\n\u00a0<\/span> \r\nAnalize<\/strong> \r\n\u00a0<\/span> \r\nFormatul \u201eHypermarketului de analize medicale\u201d oferit pacien\u021bilor, care presupune, \u00een primul r\u00e2nd, o selec\u021bie larg\u0103 a acestora, s-a justificat pe deplin. Tot mai mul\u021bi pacien\u021bi, efectueaz\u0103 analize la pre\u021buri accesibile f\u0103r\u0103 a pleca peste hotare. Acest lucru a devenit posibil datorit\u0103 cooper\u0103rii str\u00e2nse cu cele mai mari companii europene de diagnosticare - MDI LABOR LIMBACH, CEGAT, CENATA \u0219i altele.<\/span> \r\n\u00a0<\/span> \r\nMedici<\/strong> \r\n\u00a0<\/span> \r\n\u00cen urm\u0103 cu c\u00e2\u021biva ani, \u00een structura ALFA diagnostica au ap\u0103rut primele subdiviziuni clinice - Clinica Medical\u0103 Multidisciplinar\u0103 ALFAMED (alfamed.md) \u0219i Centrul Interna\u021bional de Alergologie Molecular\u0103 ALFAllergy (alergie.md).<\/span> \r\n\u00a0<\/span> \r\nLa ALFAMED, pacien\u021bii pot beneficia de asisten\u021b\u0103 calificat\u0103 de la medici cu o vast\u0103 experien\u021b\u0103 profesional\u0103 \u00een pediatrie, gastroologie, endocrinologie, dermatologie, pot fi supu\u0219i examin\u0103rilor ecografice etc.<\/span> \r\n\u00a0<\/span> \r\nMedicii ALFAllergy ofer\u0103 \u00eengrijiri de specialitate pacien\u021bilor care sufer\u0103 de rinit\u0103 alergic\u0103, dermatit\u0103 atopic\u0103 \u0219i de contact, alergii alimentare \u0219i la medicamente, astm bron\u0219ic \u0219i angioedem.<\/span> \r\nDoar la ALFAllergy, pentru pacien\u021bi este diponibil\u0103 imunoterapia specific\u0103 alergenilor pentru alergii la ambrozie, ierburi cu \u00eenflorire timpurie, acarieni de praf de cas\u0103.<\/span> \r\n\u00a0<\/span> \r\nInova\u021bii<\/strong> \r\n\u00a0<\/span> \r\nALFA diagnostica, prima din Moldova, a implementat cu succes ultimele realiz\u0103ri \u00een domeniul \u00eenv\u0103\u021b\u0103rii automate \u0219i al inteligen\u021bei artificiale, care sunt utilizate activ de speciali\u0219ti din SUA \u0219i Europa. Prima este analiza automat\u0103 a imaginilor cu raze X \u0219i CT ale toracelui pentru a diagnostica pneumonia COVID-19 \u0219i alte boli pulmonare (radlogics.md). A doua este analiza automat\u0103 a ecografiei volumetrice a forma\u021biunilor mamare pentru diagnosticarea cancerului de s\u00e2n (alfamed.md).<\/span> \r\n\u00cen esen\u021b\u0103, aceste decizii de diagnostic reprezint\u0103 o \u201ea doua opinie\u201d \u00een interpretarea imaginilor medicale.<\/span> \r\n\u00a0<\/span> \r\nALFA diagnostica \u2013 \u00cencredere din prima clip\u0103<\/em> \r\n\u00a0<\/span> \r\n022 82 44 44<\/strong> \r\nalfalab.m<\/strong>d<\/strong>\u00a0\u00a0\u00a0<\/span>","description_clear":"\u00cen data de 9 decembrie 2016, ALFA diagnostica \u0219i-a deschis u\u0219ile pentru primii s\u0103i pacien\u021bi, care au efectuat analize aici pentru prima dat\u0103. P\u00e2n\u0103 \u00een prezent, num\u0103rul pacien\u021bilor examina\u021bi s-a apropiat deja de 500.000, iar num\u0103rul analizelor efectuate a dep\u0103\u0219it 2 500 000!\r\n\u00a0\r\nCalitate\r\n\u00a0\r\n\u00cen diagnosticul de laborator, calitatea este o valoare special\u0103, care include at\u00e2t acurate\u021bea \u0219i fiabilitatea, c\u00e2t \u0219i beneficiul clinic. \u00cenc\u0103 de la \u00eenfiin\u021bare, principalele eforturi ale companiei au fost \u00eendreptate c\u0103tre asigurarea calit\u0103\u021bii corespunz\u0103toare \u2013 formarea continu\u0103 a personalului, noi analizoare, tehnologii, \u00eembun\u0103t\u0103\u021birea sistemului de control al calit\u0103\u021bii, analiza constant\u0103 \u0219i eliminarea oric\u0103ror obstacole care afecteaz\u0103 calitatea.\r\n\u00a0\r\nAnalize\r\n\u00a0\r\nFormatul \u201eHypermarketului de analize medicale\u201d oferit pacien\u021bilor, care presupune, \u00een primul r\u00e2nd, o selec\u021bie larg\u0103 a acestora, s-a justificat pe deplin. Tot mai mul\u021bi pacien\u021bi, efectueaz\u0103 analize la pre\u021buri accesibile f\u0103r\u0103 a pleca peste hotare. Acest lucru a devenit posibil datorit\u0103 cooper\u0103rii str\u00e2nse cu cele mai mari companii europene de diagnosticare - MDI LABOR LIMBACH, CEGAT, CENATA \u0219i altele.\r\n\u00a0\r\nMedici\r\n\u00a0\r\n\u00cen urm\u0103 cu c\u00e2\u021biva ani, \u00een structura ALFA diagnostica au ap\u0103rut primele subdiviziuni clinice - Clinica Medical\u0103 Multidisciplinar\u0103 ALFAMED (alfamed.md) \u0219i Centrul Interna\u021bional de Alergologie Molecular\u0103 ALFAllergy (alergie.md).\r\n\u00a0\r\nLa ALFAMED, pacien\u021bii pot beneficia de asisten\u021b\u0103 calificat\u0103 de la medici cu o vast\u0103 experien\u021b\u0103 profesional\u0103 \u00een pediatrie, gastroologie, endocrinologie, dermatologie, pot fi supu\u0219i examin\u0103rilor ecografice etc.\r\n\u00a0\r\nMedicii ALFAllergy ofer\u0103 \u00eengrijiri de specialitate pacien\u021bilor care sufer\u0103 de rinit\u0103 alergic\u0103, dermatit\u0103 atopic\u0103 \u0219i de contact, alergii alimentare \u0219i la medicamente, astm bron\u0219ic \u0219i angioedem.\r\nDoar la ALFAllergy, pentru pacien\u021bi este diponibil\u0103 imunoterapia specific\u0103 alergenilor pentru alergii la ambrozie, ierburi cu \u00eenflorire timpurie, acarieni de praf de cas\u0103.\r\n\u00a0\r\nInova\u021bii\r\n\u00a0\r\nALFA diagnostica, prima din Moldova, a implementat cu succes ultimele realiz\u0103ri \u00een domeniul \u00eenv\u0103\u021b\u0103rii automate \u0219i al inteligen\u021bei artificiale, care sunt utilizate activ de speciali\u0219ti din SUA \u0219i Europa. Prima este analiza automat\u0103 a imaginilor cu raze X \u0219i CT ale toracelui pentru a diagnostica pneumonia COVID-19 \u0219i alte boli pulmonare (radlogics.md). A doua este analiza automat\u0103 a ecografiei volumetrice a forma\u021biunilor mamare pentru diagnosticarea cancerului de s\u00e2n (alfamed.md).\r\n\u00cen esen\u021b\u0103, aceste decizii de diagnostic reprezint\u0103 o \u201ea doua opinie\u201d \u00een interpretarea imaginilor medicale.\r\n\u00a0\r\nALFA diagnostica \u2013 \u00cencredere din prima clip\u0103\r\n\u00a0\r\n022 82 44 44\r\nalfalab.md\u00a0\u00a0\u00a0","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/461\/1","url":"\/ro\/magazine\/alfa-diagnostica-5-ani-de-activitate-de-succes-461","url_full":"https:\/\/alfalab.md\/ro\/magazine\/alfa-diagnostica-5-ani-de-activitate-de-succes-461","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/alfa-diagnostica-5-ani-de-activitate-de-succes-461","show_startdate_d":"","show_enddate_d":"","date_d":"2021-12-09","show_startdate_text":"","show_enddate_text":"","date_text":"2021-12-09","date_day":"09","date_month":"Decembrie","date_published":"2021-12-14","date_modify":"2021-12-14","image_id":"202","image_ids":["202"],"image_url":"\/files\/getfile\/202\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/202\/","activegallery":[{"id":"253","parentclass":"magazine","idparentclass":"461","order":"1","idfile":"202","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/202\/","name":"63.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"460","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1637316000","views":null,"showonhome":"0","magazinetype":"2","name":"Imunitatea T-celular\u0103","author":"author blog meta","info":null,"title":"Imunitatea T-celular\u0103","urlsuffix":null,"description":"ALFA diagnostica a implimentat primul test pentru imunitatea<\/strong> \r\nT-celular\u0103 c\u0103tre COVID-19<\/strong> \r\n\u00a0 \r\nTestul este conceput pentru a evalua imunitatea celulelor T c\u0103tre COVID-19 \u0219i permite detectarea limfocitelor T specifice din s\u00e2nge, care r\u0103spund la anumi\u021bi antigeni ai coronavirusului SARS-CoV-2.<\/em> \r\n\u00a0 \r\nDou\u0103 ramuri ale imunit\u0103\u021bii<\/strong> \r\nAnticorpii\u00a0(imunitate umoral\u0103)<\/em>\u00a0protejeaz\u0103 celulele umane de infec\u021bia cu virus \u0219i ofer\u0103 protec\u021bie pentru un timp relativ scurt (6-7 luni la majoritatea oamenilor). \r\n\u00a0 \r\nLimfocitele T\u00a0(imunitatea celular\u0103<\/em>) sunt primele care reac\u021bioneaz\u0103 la contactul cu virusul, regleaz\u0103 produc\u021bia de anticorpi \u0219i distrug celulele deja infectate, \u00eentrerup\u00e2nd astfel multiplicarea virusului. \u00cen acela\u0219i timp, unele dintre limfocitele T sunt transformate \u00een limfocite T de \u201ememorie\u201d, care, la contactul repetat cu virusul, sunt activate rapid, ceea ce reduce drastic riscul de re-\u00eemboln\u0103vire. \r\n\u00a0 \r\nAdic\u0103, limfocitele T de \u201ememorie\u201d la marea majoritate a oamenilor apar dup\u0103 o boal\u0103 suportat\u0103\/actual\u0103 (inclusiv f\u0103r\u0103 simptome sau f\u0103r\u0103 anticorpi) sau imunizare (vaccinare).<\/em> \r\n\u00a0 \r\nDe ce se evalueaz\u0103 imunitatea celulelor T<\/strong> \r\nDeoarece anticorpii \u0219i limfocitele T sunt dou\u0103 ramuri ale imunit\u0103\u021bii dob\u00e2ndite, pentru o \u00een\u021belegere complet\u0103 a imunit\u0103\u021bii, este necesar s\u0103 se m\u0103soare nu numai concentra\u021bia de anticorpi, ci \u0219i activitatea \u201ememoriei\u201d a limfocitelor T. \r\n\u00a0 \r\nCum se m\u0103soar\u0103 activitatea \u201ememoriei\u201d limfocitelor T<\/strong> \r\nLimfocitele T ale unei persoane care a fost supus\u0103 sau vaccinat\u0103 \u00eempotriva COVID-19 difer\u0103 de limfocitele T ale aceleia\u0219i persoane \u00eenainte de \u00eemboln\u0103vire sau vaccinare prin faptul c\u0103, ca r\u0103spuns la contactul repetat cu virusul\/vaccinul, \u00eencep s\u0103 produc\u0103 cantit\u0103\u021bi mari de interferon gamma, care joac\u0103 un rol cheie \u00een imunitate. \r\n\u00a0 \r\nPe acest principiu se construie\u0219te o platform\u0103 tehnologic\u0103 - limfocitele sunt izolate din s\u00e2ngele venos uman, la care se adaug\u0103 o protein\u0103 viral\u0103 (proteina S1) \u0219i se m\u0103soar\u0103 concentra\u021bia interferonului gamma eliberat. \r\n\u00a0 \r\nCum se evalueaz\u0103 rezultatul testului<\/strong> \r\nDac\u0103 concentra\u021bia de interferon gamma ca r\u0103spuns la stimularea limfocitelor T este > 200 mIU\/mL, rezultatul testului este considerat pozitiv, 100-200 - echivoc, <100 - negativ. \r\n\u00a0 \r\nCum s\u0103 interpret\u0103m rezultatele<\/strong> \r\nPozitiv<\/em>\u00a0- un r\u0103spuns imun al celulelor T format dup\u0103 o infec\u021bie trecut\u0103\/actual\u0103 (inclusiv asimptomatic\u0103) sau vaccinare. \r\nNegativ<\/em>\u00a0- f\u0103r\u0103 r\u0103spuns imun al celulelor T (nu pot fi excluse infec\u021bia acut\u0103 sau vaccinarea recent\u0103). \r\nEchivoc<\/em>\u00a0- este necesar\u0103 repetarea analizei. \r\n\u00a0 \r\nCui este recomandat\u0103 aceast\u0103 investiga\u021bie?<\/strong> \r\nPersoanelor dup\u0103 imunizare (vaccinare). \r\nPersoanelor dup\u0103 ce au suferit COVID-19 (mai ales f\u0103r\u0103 anticorpi). \r\nPersoanelor cu imunitate redus\u0103 (v\u00e2rstnici, sl\u0103bi\u021bi sau afla\u021bi la hemodializ\u0103) \u2013 deoarece nivelurile de anticorpi pot fi sc\u0103zute sau inadecvate, iar determinarea r\u0103spunsului imun al celulelor T poate oferi o evaluare mult mai complet\u0103 a ceea ce se \u00eent\u00e2mpl\u0103. \r\n\u00a0 \r\nCaracteristici de performan\u021b\u0103<\/strong> \r\nSensibilitate diagnostic\u0103 - 97,9%, specificitate diagnostic\u0103 - 97,7%. \r\n\u00a0 \r\nStatut de reglementare<\/strong> \r\nCE-IVD (aprobat pentru diagnosticul clinic de laborator). \r\n\u00a0 \r\nInforma\u021bii suplimentare<\/strong> \r\nPret: 1200 lei \r\nTimp: 3 zile lucratoare \r\nMod de preparare: pe stomacul gol sau la 4 ore dup\u0103 mas\u0103 \r\nBiomaterial: s\u00e2nge venos \r\n\u00a0 \r\nUnde s\u0103 te testezi \u00een Chi\u0219in\u0103u<\/strong> \r\nStr. N. Testemitanu, 21 (luni - miercuri, 07-30 - 11-00) \r\nStr. C. V\u00e2rnav, 8 (luni - miercuri, 07-30 - 09-00) \r\nStr. A. Russo, 15 (luni - miercuri, 07-30 - 09-00) \r\nStr. Bucuresti, 116 (luni - miercuri, 07-30 - 09-00) \r\nStr. Decebal, 72\/6 (luni - miercuri, 07-30 - 09-00) \r\nStr. Mircea cel Batrin, 3\/2 (luni - miercuri, 07-30 - 09-00) \r\n\u00a0 \r\nCentru de contact<\/strong> \r\n022 82 44 44 \r\nalfalab.md<\/u><\/span><\/span>","description_clear":"ALFA diagnostica a implimentat primul test pentru imunitatea\r\nT-celular\u0103 c\u0103tre COVID-19\r\n\u00a0\r\nTestul este conceput pentru a evalua imunitatea celulelor T c\u0103tre COVID-19 \u0219i permite detectarea limfocitelor T specifice din s\u00e2nge, care r\u0103spund la anumi\u021bi antigeni ai coronavirusului SARS-CoV-2.\r\n\u00a0\r\nDou\u0103 ramuri ale imunit\u0103\u021bii\r\nAnticorpii\u00a0(imunitate umoral\u0103)\u00a0protejeaz\u0103 celulele umane de infec\u021bia cu virus \u0219i ofer\u0103 protec\u021bie pentru un timp relativ scurt (6-7 luni la majoritatea oamenilor).\r\n\u00a0\r\nLimfocitele T\u00a0(imunitatea celular\u0103) sunt primele care reac\u021bioneaz\u0103 la contactul cu virusul, regleaz\u0103 produc\u021bia de anticorpi \u0219i distrug celulele deja infectate, \u00eentrerup\u00e2nd astfel multiplicarea virusului. \u00cen acela\u0219i timp, unele dintre limfocitele T sunt transformate \u00een limfocite T de \u201ememorie\u201d, care, la contactul repetat cu virusul, sunt activate rapid, ceea ce reduce drastic riscul de re-\u00eemboln\u0103vire.\r\n\u00a0\r\nAdic\u0103, limfocitele T de \u201ememorie\u201d la marea majoritate a oamenilor apar dup\u0103 o boal\u0103 suportat\u0103\/actual\u0103 (inclusiv f\u0103r\u0103 simptome sau f\u0103r\u0103 anticorpi) sau imunizare (vaccinare).\r\n\u00a0\r\nDe ce se evalueaz\u0103 imunitatea celulelor T\r\nDeoarece anticorpii \u0219i limfocitele T sunt dou\u0103 ramuri ale imunit\u0103\u021bii dob\u00e2ndite, pentru o \u00een\u021belegere complet\u0103 a imunit\u0103\u021bii, este necesar s\u0103 se m\u0103soare nu numai concentra\u021bia de anticorpi, ci \u0219i activitatea \u201ememoriei\u201d a limfocitelor T.\r\n\u00a0\r\nCum se m\u0103soar\u0103 activitatea \u201ememoriei\u201d limfocitelor T\r\nLimfocitele T ale unei persoane care a fost supus\u0103 sau vaccinat\u0103 \u00eempotriva COVID-19 difer\u0103 de limfocitele T ale aceleia\u0219i persoane \u00eenainte de \u00eemboln\u0103vire sau vaccinare prin faptul c\u0103, ca r\u0103spuns la contactul repetat cu virusul\/vaccinul, \u00eencep s\u0103 produc\u0103 cantit\u0103\u021bi mari de interferon gamma, care joac\u0103 un rol cheie \u00een imunitate.\r\n\u00a0\r\nPe acest principiu se construie\u0219te o platform\u0103 tehnologic\u0103 - limfocitele sunt izolate din s\u00e2ngele venos uman, la care se adaug\u0103 o protein\u0103 viral\u0103 (proteina S1) \u0219i se m\u0103soar\u0103 concentra\u021bia interferonului gamma eliberat.\r\n\u00a0\r\nCum se evalueaz\u0103 rezultatul testului\r\nDac\u0103 concentra\u021bia de interferon gamma ca r\u0103spuns la stimularea limfocitelor T este > 200 mIU\/mL, rezultatul testului este considerat pozitiv, 100-200 - echivoc, <100 - negativ.\r\n\u00a0\r\nCum s\u0103 interpret\u0103m rezultatele\r\nPozitiv\u00a0- un r\u0103spuns imun al celulelor T format dup\u0103 o infec\u021bie trecut\u0103\/actual\u0103 (inclusiv asimptomatic\u0103) sau vaccinare.\r\nNegativ\u00a0- f\u0103r\u0103 r\u0103spuns imun al celulelor T (nu pot fi excluse infec\u021bia acut\u0103 sau vaccinarea recent\u0103).\r\nEchivoc\u00a0- este necesar\u0103 repetarea analizei.\r\n\u00a0\r\nCui este recomandat\u0103 aceast\u0103 investiga\u021bie?\r\nPersoanelor dup\u0103 imunizare (vaccinare).\r\nPersoanelor dup\u0103 ce au suferit COVID-19 (mai ales f\u0103r\u0103 anticorpi).\r\nPersoanelor cu imunitate redus\u0103 (v\u00e2rstnici, sl\u0103bi\u021bi sau afla\u021bi la hemodializ\u0103) \u2013 deoarece nivelurile de anticorpi pot fi sc\u0103zute sau inadecvate, iar determinarea r\u0103spunsului imun al celulelor T poate oferi o evaluare mult mai complet\u0103 a ceea ce se \u00eent\u00e2mpl\u0103.\r\n\u00a0\r\nCaracteristici de performan\u021b\u0103\r\nSensibilitate diagnostic\u0103 - 97,9%, specificitate diagnostic\u0103 - 97,7%.\r\n\u00a0\r\nStatut de reglementare\r\nCE-IVD (aprobat pentru diagnosticul clinic de laborator).\r\n\u00a0\r\nInforma\u021bii suplimentare\r\nPret: 1200 lei\r\nTimp: 3 zile lucratoare\r\nMod de preparare: pe stomacul gol sau la 4 ore dup\u0103 mas\u0103\r\nBiomaterial: s\u00e2nge venos\r\n\u00a0\r\nUnde s\u0103 te testezi \u00een Chi\u0219in\u0103u\r\nStr. N. Testemitanu, 21 (luni - miercuri, 07-30 - 11-00)\r\nStr. C. V\u00e2rnav, 8 (luni - miercuri, 07-30 - 09-00)\r\nStr. A. Russo, 15 (luni - miercuri, 07-30 - 09-00)\r\nStr. Bucuresti, 116 (luni - miercuri, 07-30 - 09-00)\r\nStr. Decebal, 72\/6 (luni - miercuri, 07-30 - 09-00)\r\nStr. Mircea cel Batrin, 3\/2 (luni - miercuri, 07-30 - 09-00)\r\n\u00a0\r\nCentru de contact\r\n022 82 44 44\r\nalfalab.md","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/460\/1","url":"\/ro\/magazine\/imunitatea-t-celulara-460","url_full":"https:\/\/alfalab.md\/ro\/magazine\/imunitatea-t-celulara-460","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/imunitatea-t-celulara-460","show_startdate_d":"","show_enddate_d":"","date_d":"2021-11-19","show_startdate_text":"","show_enddate_text":"","date_text":"2021-11-19","date_day":"19","date_month":"Noiembrie","date_published":"2021-12-13","date_modify":"2021-12-13","image_id":"200","image_ids":["200"],"image_url":"\/files\/getfile\/200\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/200\/","activegallery":[{"id":"252","parentclass":"magazine","idparentclass":"460","order":"1","idfile":"200","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/200\/","name":"62.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"458","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1622106000","views":null,"showonhome":"1","magazinetype":"2","name":"Evaluarea complex\u0103 a imunit\u0103\u021bii celulare","author":"author blog meta","info":null,"title":"Evaluarea complex\u0103 a imunit\u0103\u021bii celulare","urlsuffix":null,"description":"ALFA diagnostica a lansat cu succes un nou test\u00a0<\/strong><\/em>\u2013\u00a0<\/strong>imunofenotiparea limfocitelor<\/strong><\/em>, cu ajutorul c\u0103ruia speciali\u0219tii \u00een imunologie clinic\u0103 pot evalua starea func\u021bional\u0103 a sistemului imun celular.<\/strong><\/em> \r\n \r\nTestul este recomandat pacien\u021bilor care sufer\u0103 de diferite maladii cronice, infec\u021bii respiratorii frecvente, herpes recurent, febr\u0103 prelungit\u0103 de genez\u0103 nedeterminat\u0103, suspec\u021bie la imunodeficien\u021be dob\u00e2ndite sau congenitale, boli alergice \u0219i oncologice, pentru evaluarea tratamentul citostatic, imunosupresiv \u0219i imunomodulator. \r\n \r\nTestul m\u0103soar\u0103 cantitativ subpopula\u021biile principalele de limfocite T \u0219i B din s\u00e2nge \u0219i raportul lor \u2013 \u00een total 15 parametri. Investiga\u021bia este realizat\u0103 cu ajutorul tehnologiei citometriei de flux (Beckman Coulter, SUA).\r\n<div>\r\n<hr align=\"left\" noshade=\"noshade\" size=\"2\" width=\"100%\" \/><\/div>\r\n\r\n<table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"width:865px;\" width=\"865\">\r\n\t<tbody>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:271px;height:20px;\">CD3+CD45+ (%)<\/td>\r\n\t\t\t<td style=\"width:595px;height:20px;\">T-limfocite (procente), CD3+CD45+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD3+CD45+ (#)<\/td>\r\n\t\t\t<td style=\"height:20px;\">T-limfocite (num\u0103r absolut), CD3+CD45+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD3+CD4+CD45+ (%)<\/td>\r\n\t\t\t<td style=\"height:20px;\">T-helperi (procente), CD3+CD4+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD3+CD4+CD45+ (#)<\/td>\r\n\t\t\t<td style=\"height:20px;\">T-helperi (num\u0103r absolut), CD3+CD4+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD3+CD8+CD45+ (%)<\/td>\r\n\t\t\t<td style=\"height:20px;\">T-citotoxice (procente), CD3+CD8+\u00a0<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD3+CD8+CD45+ (#)<\/td>\r\n\t\t\t<td style=\"height:20px;\">T-citotoxice (num\u0103r absolut), CD3+CD8+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">Index T-helperi\/T-citotoxice<\/td>\r\n\t\t\t<td style=\"height:20px;\">Index CD3+CD4+\/CD3+CD8+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD3+CD56+CD45+ (%)<\/td>\r\n\t\t\t<td style=\"height:20px;\">T-limfocite - NKT (procente), CD3+CD56+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD3+CD56+CD45+ (#)<\/td>\r\n\t\t\t<td style=\"height:20px;\">T-limfocite - NKT (num\u0103r absolut), CD3+CD56+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">\u0421D3-CD56+CD45+ (%)<\/td>\r\n\t\t\t<td style=\"height:20px;\">Killeri naturali - NK (procente), CD3-CD56+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD3-CD56+CD45+ (#)<\/td>\r\n\t\t\t<td style=\"height:20px;\">Killeri naturali - NK (num\u0103r absolut), CD3-CD56+<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD19+CD3- (%)<\/td>\r\n\t\t\t<td style=\"height:20px;\">B-limfocite (procente), CD19+CD3-<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD19+CD3- (#)<\/td>\r\n\t\t\t<td style=\"height:20px;\">B-limfocite (num\u0103r absolut), CD19+CD3-<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"height:20px;\">CD3+HLA-DR+CD45+ (%)<\/td>\r\n\t\t\t<td style=\"height:20px;\">T-limfocite activate (procente), CD3+HLA-DR+\u00a0<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:271px;height:20px;\">CD3+HLA-DR+CD45+ (#)<\/td>\r\n\t\t\t<td style=\"height:20px;\">T-limfocite activate (num\u0103r absolut), CD3+HLA-DR+<\/td>\r\n\t\t<\/tr>\r\n\t<\/tbody>\r\n<\/table>\r\n\r\n<div>\r\n<hr align=\"left\" noshade=\"noshade\" size=\"2\" width=\"100%\" \/><\/div>\r\nPrelevarea s\u00e2ngelui se efectueaz\u0103 la Alfa Diagnostica, adresa: str. N. Testemi\u021banu, 21,\u00a0<\/em>\u00een\u00a0fiecare zi de vineri<\/em>\u00a0de la\u00a0<\/em>8<\/em>\u00a0la\u00a0<\/em>9<\/em>\u00a0diminea\u021ba.<\/em> \r\nPentru interpretarea clinic\u0103 a rezultatelor test\u0103rii, v\u0103 rug\u0103m s\u0103 contacta\u021bi Centrul Interna\u021bional de Alergologie Molecular\u0103\u00a0<a href=\"https:\/\/alergie.md\/\" target=\"_blank\">ALFAllergy<\/a><\/strong>","description_clear":"ALFA diagnostica a lansat cu succes un nou test\u00a0\u2013\u00a0imunofenotiparea limfocitelor, cu ajutorul c\u0103ruia speciali\u0219tii \u00een imunologie clinic\u0103 pot evalua starea func\u021bional\u0103 a sistemului imun celular.\r\n\r\nTestul este recomandat pacien\u021bilor care sufer\u0103 de diferite maladii cronice, infec\u021bii respiratorii frecvente, herpes recurent, febr\u0103 prelungit\u0103 de genez\u0103 nedeterminat\u0103, suspec\u021bie la imunodeficien\u021be dob\u00e2ndite sau congenitale, boli alergice \u0219i oncologice, pentru evaluarea tratamentul citostatic, imunosupresiv \u0219i imunomodulator.\r\n\r\nTestul m\u0103soar\u0103 cantitativ subpopula\u021biile principalele de limfocite T \u0219i B din s\u00e2nge \u0219i raportul lor \u2013 \u00een total 15 parametri. Investiga\u021bia este realizat\u0103 cu ajutorul tehnologiei citometriei de flux (Beckman Coulter, SUA).\r\n\r\n\r\n\r\n\r\n\t\r\n\t\t\r\n\t\t\tCD3+CD45+ (%)\r\n\t\t\tT-limfocite (procente), CD3+CD45+\r\n\t\t\r\n\t\t\r\n\t\t\tCD3+CD45+ (#)\r\n\t\t\tT-limfocite (num\u0103r absolut), CD3+CD45+\r\n\t\t\r\n\t\t\r\n\t\t\tCD3+CD4+CD45+ (%)\r\n\t\t\tT-helperi (procente), CD3+CD4+\r\n\t\t\r\n\t\t\r\n\t\t\tCD3+CD4+CD45+ (#)\r\n\t\t\tT-helperi (num\u0103r absolut), CD3+CD4+\r\n\t\t\r\n\t\t\r\n\t\t\tCD3+CD8+CD45+ (%)\r\n\t\t\tT-citotoxice (procente), CD3+CD8+\u00a0\r\n\t\t\r\n\t\t\r\n\t\t\tCD3+CD8+CD45+ (#)\r\n\t\t\tT-citotoxice (num\u0103r absolut), CD3+CD8+\r\n\t\t\r\n\t\t\r\n\t\t\tIndex T-helperi\/T-citotoxice\r\n\t\t\tIndex CD3+CD4+\/CD3+CD8+\r\n\t\t\r\n\t\t\r\n\t\t\tCD3+CD56+CD45+ (%)\r\n\t\t\tT-limfocite - NKT (procente), CD3+CD56+\r\n\t\t\r\n\t\t\r\n\t\t\tCD3+CD56+CD45+ (#)\r\n\t\t\tT-limfocite - NKT (num\u0103r absolut), CD3+CD56+\r\n\t\t\r\n\t\t\r\n\t\t\t\u0421D3-CD56+CD45+ (%)\r\n\t\t\tKilleri naturali - NK (procente), CD3-CD56+\r\n\t\t\r\n\t\t\r\n\t\t\tCD3-CD56+CD45+ (#)\r\n\t\t\tKilleri naturali - NK (num\u0103r absolut), CD3-CD56+\r\n\t\t\r\n\t\t\r\n\t\t\tCD19+CD3- (%)\r\n\t\t\tB-limfocite (procente), CD19+CD3-\r\n\t\t\r\n\t\t\r\n\t\t\tCD19+CD3- (#)\r\n\t\t\tB-limfocite (num\u0103r absolut), CD19+CD3-\r\n\t\t\r\n\t\t\r\n\t\t\tCD3+HLA-DR+CD45+ (%)\r\n\t\t\tT-limfocite activate (procente), CD3+HLA-DR+\u00a0\r\n\t\t\r\n\t\t\r\n\t\t\tCD3+HLA-DR+CD45+ (#)\r\n\t\t\tT-limfocite activate (num\u0103r absolut), CD3+HLA-DR+\r\n\t\t\r\n\t\r\n\r\n\r\n\r\n\r\nPrelevarea s\u00e2ngelui se efectueaz\u0103 la Alfa Diagnostica, adresa: str. N. Testemi\u021banu, 21,\u00a0\u00een\u00a0fiecare zi de vineri\u00a0de la\u00a08\u00a0la\u00a09\u00a0diminea\u021ba.\r\nPentru interpretarea clinic\u0103 a rezultatelor test\u0103rii, v\u0103 rug\u0103m s\u0103 contacta\u021bi Centrul Interna\u021bional de Alergologie Molecular\u0103\u00a0ALFAllergy","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/458\/1","url":"\/ro\/magazine\/evaluarea-complexa-a-imunitatii-celulare-458","url_full":"https:\/\/alfalab.md\/ro\/magazine\/evaluarea-complexa-a-imunitatii-celulare-458","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/evaluarea-complexa-a-imunitatii-celulare-458","show_startdate_d":"","show_enddate_d":"","date_d":"2021-05-27","show_startdate_text":"","show_enddate_text":"","date_text":"2021-05-27","date_day":"27","date_month":"Mai","date_published":"2021-11-18","date_modify":"2021-11-18","image_id":"199","image_ids":["199"],"image_url":"\/files\/getfile\/199\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/199\/","activegallery":[{"id":"251","parentclass":"magazine","idparentclass":"458","order":"1","idfile":"199","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/199\/","name":"61.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"457","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1604743200","views":null,"showonhome":"1","magazinetype":"2","name":"Trichomonas vaginalis \u00een urin\u0103 \u2013 primul test \u00een Moldova!","author":"author blog meta","info":null,"title":"Trichomonas vaginalis \u00een urin\u0103 \u2013 primul test \u00een Moldova!","urlsuffix":null,"description":"ALFA diagnostica a implementat cu succes un nou test de laborator Xpert\u00ae TV - primul \u0219i singurul test molecular ultrasensibil \u00a0\u00een Moldova pentru detectarea Trichomonas vaginalis \u00een proba de urin\u0103 la b\u0103rba\u021bi \u0219i femei (cu \u0219i f\u0103r\u0103 simptome). \r\n\u00a0 \r\nDiagnosticele tradi\u021bionale nu sunt perfecte<\/strong><\/span>\r\n<ul>\r\n\t<li>Identificarea agentului patogen Trichomonas vaginalis este \u00eentotdeauna problematic\u0103 din mai multe motive: caracteristici ale biologiei patogene, dificult\u0103\u021bi de cultivare, mimica \u021bintelor moleculare etc.<\/li>\r\n<\/ul>\r\nAbordare inovatoare<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Testul TV xpert\u00ae este conceput pentru a identifica \u021bintele de ADN molecular trichomonas vaginalis atent selectate.<\/li>\r\n<\/ul>\r\nCaracteristici de diagnosticare<\/strong><\/span> \r\n\u00a0\r\n<table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"width:680px;\" width=\"680\">\r\n\t<tbody>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">Urin\u0103 (b\u0103rba\u021bi)<\/strong><\/td>\r\n\t\t\t<td style=\"width:246px;\">\u00a0<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">\u00a0 Sensibilitate clinic\u0103,%<\/td>\r\n\t\t\t<td style=\"width:246px;\">89.1<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">\u00a0 Specificitate clinic\u0103, %<\/td>\r\n\t\t\t<td style=\"width:246px;\">99.3<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">\u00a0 Sensibilitate\u00a0analitic\u0103 \/ limita de detec\u021bie<\/td>\r\n\t\t\t<td style=\"width:246px;\">3 celule la 1 ml<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">Urin\u0103 (femei)<\/strong><\/td>\r\n\t\t\t<td style=\"width:246px;\">\u00a0<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">\u00a0 Sensibilitate clinic\u0103,%<\/td>\r\n\t\t\t<td style=\"width:246px;\">98.4<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">\u00a0 Specificitate clinic\u0103, %<\/td>\r\n\t\t\t<td style=\"width:246px;\">99.7<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">Raclaj\u00a0 endocervical<\/strong><\/td>\r\n\t\t\t<td style=\"width:246px;\">\u00a0<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">\u00a0 Sensibilitate clinic\u0103,%<\/td>\r\n\t\t\t<td style=\"width:246px;\">98.9<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:434px;\">\u00a0 Specificitate clinic\u0103, %<\/td>\r\n\t\t\t<td style=\"width:246px;\">98.9<\/td>\r\n\t\t<\/tr>\r\n\t<\/tbody>\r\n<\/table>\r\n\u00a0 \r\nStatutul de reglementare<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>IVD, CE, CLIA-waived, FDA-approved (Food and Drug Administration)<\/li>\r\n<\/ul>\r\nForma de prezentare a rezultatului<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>DETECTAT sau NEDETECTAT<\/li>\r\n<\/ul>\r\nMaterial de cercetare<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Urina de diminea\u021b\u0103, prima por\u021bie (pentru b\u0103rba\u021bi \u0219i femei), r\u0103zuirea celulelor epiteliale din endocervix sau vagin.<\/li>\r\n<\/ul>\r\nMetoda de cercetare<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Reac\u021bia \u00een lan\u021b a polimerazei \u00een timp real (analiza automat\u0103 a multiplexului).<\/li>\r\n<\/ul>\r\nPreg\u0103tirea pentru cercetare<\/strong><\/span> \r\nFemei<\/strong>\r\n\r\n<ul>\r\n\t<li>Cu 1 zi \u00eenainte de test, nu utiliza\u021bi creme vaginale, supozitoare sau tampoane \u0219i, \u00een ziua testului, nu efectua\u021bi o toalet\u0103 igienic\u0103 a organelor genitale \u0219i du\u0219uri folosind geluri \u0219i \/ sau antiseptice. Nu este recomandat s\u0103 face\u021bi test \u00een timpul menstrua\u021biei.<\/li>\r\n<\/ul>\r\nB\u0103rba\u021bi<\/strong>\r\n\r\n<ul>\r\n\t<li>F\u0103r\u0103 preg\u0103tire<\/li>\r\n<\/ul>\r\nTimp analitic<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>\u00cen termen de 3 ore - pentru pacien\u021bii care au trecut testul la Laboratorul Central ALFA diagnostica de pe strada Testemi\u021banu, nr.21<\/li>\r\n\t<li>\u00cen timpul zilei de lucru - pentru pacien\u021bii care au trecut analiza \u00een filialele laboratorului din mun. Chi\u0219in\u0103u.<\/li>\r\n\t<li>\u00cen a doua zi - pentru pacien\u021bii care au trecut testul la filiala laboratorului din mun. B\u0103lti.<\/li>\r\n<\/ul>","description_clear":"ALFA diagnostica a implementat cu succes un nou test de laborator Xpert\u00ae TV - primul \u0219i singurul test molecular ultrasensibil \u00a0\u00een Moldova pentru detectarea Trichomonas vaginalis \u00een proba de urin\u0103 la b\u0103rba\u021bi \u0219i femei (cu \u0219i f\u0103r\u0103 simptome).\r\n\u00a0\r\nDiagnosticele tradi\u021bionale nu sunt perfecte\r\n\r\n\tIdentificarea agentului patogen Trichomonas vaginalis este \u00eentotdeauna problematic\u0103 din mai multe motive: caracteristici ale biologiei patogene, dificult\u0103\u021bi de cultivare, mimica \u021bintelor moleculare etc.\r\n\r\nAbordare inovatoare\r\n\r\n\r\n\tTestul TV xpert\u00ae este conceput pentru a identifica \u021bintele de ADN molecular trichomonas vaginalis atent selectate.\r\n\r\nCaracteristici de diagnosticare\r\n\u00a0\r\n\r\n\t\r\n\t\t\r\n\t\t\tUrin\u0103 (b\u0103rba\u021bi)\r\n\t\t\t\u00a0\r\n\t\t\r\n\t\t\r\n\t\t\t\u00a0 Sensibilitate clinic\u0103,%\r\n\t\t\t89.1\r\n\t\t\r\n\t\t\r\n\t\t\t\u00a0 Specificitate clinic\u0103, %\r\n\t\t\t99.3\r\n\t\t\r\n\t\t\r\n\t\t\t\u00a0 Sensibilitate\u00a0analitic\u0103 \/ limita de detec\u021bie\r\n\t\t\t3 celule la 1 ml\r\n\t\t\r\n\t\t\r\n\t\t\tUrin\u0103 (femei)\r\n\t\t\t\u00a0\r\n\t\t\r\n\t\t\r\n\t\t\t\u00a0 Sensibilitate clinic\u0103,%\r\n\t\t\t98.4\r\n\t\t\r\n\t\t\r\n\t\t\t\u00a0 Specificitate clinic\u0103, %\r\n\t\t\t99.7\r\n\t\t\r\n\t\t\r\n\t\t\tRaclaj\u00a0 endocervical\r\n\t\t\t\u00a0\r\n\t\t\r\n\t\t\r\n\t\t\t\u00a0 Sensibilitate clinic\u0103,%\r\n\t\t\t98.9\r\n\t\t\r\n\t\t\r\n\t\t\t\u00a0 Specificitate clinic\u0103, %\r\n\t\t\t98.9\r\n\t\t\r\n\t\r\n\r\n\u00a0\r\nStatutul de reglementare\r\n\r\n\r\n\tIVD, CE, CLIA-waived, FDA-approved (Food and Drug Administration)\r\n\r\nForma de prezentare a rezultatului\r\n\r\n\r\n\tDETECTAT sau NEDETECTAT\r\n\r\nMaterial de cercetare\r\n\r\n\r\n\tUrina de diminea\u021b\u0103, prima por\u021bie (pentru b\u0103rba\u021bi \u0219i femei), r\u0103zuirea celulelor epiteliale din endocervix sau vagin.\r\n\r\nMetoda de cercetare\r\n\r\n\r\n\tReac\u021bia \u00een lan\u021b a polimerazei \u00een timp real (analiza automat\u0103 a multiplexului).\r\n\r\nPreg\u0103tirea pentru cercetare\r\nFemei\r\n\r\n\r\n\tCu 1 zi \u00eenainte de test, nu utiliza\u021bi creme vaginale, supozitoare sau tampoane \u0219i, \u00een ziua testului, nu efectua\u021bi o toalet\u0103 igienic\u0103 a organelor genitale \u0219i du\u0219uri folosind geluri \u0219i \/ sau antiseptice. Nu este recomandat s\u0103 face\u021bi test \u00een timpul menstrua\u021biei.\r\n\r\nB\u0103rba\u021bi\r\n\r\n\r\n\tF\u0103r\u0103 preg\u0103tire\r\n\r\nTimp analitic\r\n\r\n\r\n\t\u00cen termen de 3 ore - pentru pacien\u021bii care au trecut testul la Laboratorul Central ALFA diagnostica de pe strada Testemi\u021banu, nr.21\r\n\t\u00cen timpul zilei de lucru - pentru pacien\u021bii care au trecut analiza \u00een filialele laboratorului din mun. Chi\u0219in\u0103u.\r\n\t\u00cen a doua zi - pentru pacien\u021bii care au trecut testul la filiala laboratorului din mun. B\u0103lti.","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/457\/1","url":"\/ro\/magazine\/trichomonas-vaginalis-in-urina-primul-test-in-moldova-457","url_full":"https:\/\/alfalab.md\/ro\/magazine\/trichomonas-vaginalis-in-urina-primul-test-in-moldova-457","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/trichomonas-vaginalis-in-urina-primul-test-in-moldova-457","show_startdate_d":"","show_enddate_d":"","date_d":"2020-11-07","show_startdate_text":"","show_enddate_text":"","date_text":"2020-11-07","date_day":"07","date_month":"Noiembrie","date_published":"2021-11-18","date_modify":"2021-11-18","image_id":"198","image_ids":["198"],"image_url":"\/files\/getfile\/198\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/198\/","activegallery":[{"id":"250","parentclass":"magazine","idparentclass":"457","order":"1","idfile":"198","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/198\/","name":"60.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"412","status":"1","fixed":"0","show_startdate":"0","show_enddate":"0","date":"1601283600","views":"0","showonhome":"1","magazinetype":"2","name":"Primul test din lume pentru detectarea anticorpilor neutralizan\u021bi SARS-CoV-2","author":"author blog meta","info":"","title":"Sia - Move Your Body (Remix 2018)","urlsuffix":"","description":"Agita\u021bia pe marginea subiectului anticorpilor pe care organismul \u00eei direc\u021bioneaz\u0103 pentru lupta cu coronavirusul nu dispare - un num\u0103r tot mai mare de persoane care au fost bolnavi (\u0219i nu numai) sunt testa\u021bi pentru anticorpi, fiind motiva\u021bi de o multitudine de cauze, dar, \u00een primul r\u00e2nd, pentru a evalua imunitatea. R\u0103spund oare testele de laborator la toate \u00eentreb\u0103rile? Ast\u0103zi, c\u00e2nd au trecut mai mult de \u0219ase luni de la \u00eenceputul epidemiei, rolul anticorpilor produ\u0219i de c\u0103tre sistemul imun \u00eempotriva SARS-CoV-2 a devenit clar\u0103. S-a dovedit c\u0103 exist\u0103 diferite categorii de anticorpi.<\/strong> \r\n\u00a0 \r\nAnticorpi care\u00a0<\/em><\/strong>LEAG\u0102<\/em><\/strong><\/span>\u00a0<\/span>virusul<\/em><\/strong>\r\n<ul>\r\n\t<li>Anume acest grup heterogen de anticorpi, este testat, ast\u0103zi, pe scar\u0103 larg\u0103 \u00een laboratoarele medicale.<\/li>\r\n<\/ul>\r\n\u00centruc\u00e2t ace\u0219ti anticorpi sunt direc\u021biona\u021bi \u00eempotriva diferitelor proteine \u200b\u200breceptor (N, S) ale virusului, detectarea lor indic\u0103, \u00een primul r\u00e2nd, contactul persoanei cu virusul, \u00een al doilea r\u00e2nd, ajut\u0103 medicii s\u0103 evalueze mai exact momentul infect\u0103rii \u0219i faza procesului. Func\u021bia de asigurare a imunit\u0103\u021bii \u00een cazul anticorpii care leag\u0103 virusul este absent\u0103, iar plasma celor care s-au recuperat de COVID-19 \u0219i care con\u021bin ace\u0219ti anticorpi este poten\u021bial ineficient\u0103. \r\n\u00a0 \r\nAnticorpi care\u00a0<\/em><\/strong>NEUTRALIZEAZ\u0102\u00a0<\/em><\/strong><\/span>virusul<\/em><\/strong>\r\n\r\n<ul>\r\n\t<li>Tradi\u021bional, ace\u0219ti anticorpi sunt determina\u021bi numai \u00een laboratoare ultra specializate, echipate s\u0103 lucreze cu viru\u0219i \u0219i culturi vii, iar tehnologia \u00een sine este biologic periculoas\u0103 \u0219i nu se aplic\u0103 pentru practica clinic\u0103 de rutin\u0103.<\/li>\r\n<\/ul>\r\nAcest tip de anticorpi este singurul care are func\u021bia de a bloca legarea SARS-CoV-2 cu receptorul ACE (enzima de conversie a angiotensinei) pe suprafa\u021ba celulei umane, ceea ce \u00eenseamn\u0103 c\u0103 previne p\u0103trunderea virusului \u00een celul\u0103 \u0219i respectiv, dezvoltarea bolii. De fapt, ace\u0219ti anticorpi neutralizeaz\u0103 activitatea virusului \u0219i formeaz\u0103 imunitate, iar plasma donatoare care le con\u021bine are poten\u021bial terapeutic. Prin urmare, cel mai important, stimularea sistemului imun pentru a produce anticorpi neutralizan\u021bi este scopul final al vaccin\u0103rii pentru a preveni COVID-19. \r\n\u00a0 \r\nTestele de laborator disponibile \u00een comer\u021b nu pot face diferen\u021ba \u00eentre anticorpii neutralizan\u021bi \u0219i anticorpii de legare.<\/em> \r\n\u00a0 \r\nPrimul test din lume pentru detectarea anticorpilor neutralizan\u021bi<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>ALFA diagnostica, unul dintre primii din Europa, care a \u00eenceput determinarea de laborator a anticorpilor\u00a0cu\u00a0<a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/A\/anticorpi-coronavirus-sars-cov-2-igg-neutralizanti-4029\">func\u021bie de neutralizare<\/span><\/a>\u00a0utiliz\u00e2nd o tehnologie brevetat\u0103, implementat\u0103 \u00eentr-o platform\u0103 pentru imunoanaliz\u0103 de rutin\u0103 \u0219i, cel mai important, f\u0103r\u0103 a fi nevoie s\u0103 se utilizeze materiale biologice vii \u0219i echipamente de protec\u021bie special\u0103. Rezultatele testului coreleaz\u0103 perfect cu rezultatele ob\u021binute prin testul clasic de neutralizare pe culturi vii infectate cu SARS-CoV-2.<\/li>\r\n\t<li>La baza primul test func\u021bional din lume, st\u0103 imitarea interac\u021biunii unui virus surogat recombinant (S1-RBD) cu un receptor de celule recombinante (ACE). La prezen\u021ba anticorpilor neutralizan\u021bi \u00een proba pacientului, legarea S1-RBD \u0219i ACE este blocat\u0103 (nu se produce nicio reac\u021bie \u00eentre ei) \u0219i invers, care este detectat\u0103 \u00een mod clar de sistemul de testare.<\/li>\r\n\t<li>Un rezultat pozitiv al testului indic\u0103 faptul c\u0103 pacientul are anticorpi eficien\u021bi care pot neutraliza activitatea virusului, ceea ce este o dovad\u0103 a prezen\u021bei imunit\u0103\u021bii \u00een perioada de timp curent\u0103. Trebuie de subliniat faptul c\u0103, detectarea anticorpilor neutralizan\u021bi nu \u00eenseamn\u0103 c\u0103 m\u0103surile individuale de prevenire a infec\u021biei pot fi ignorate.<\/li>\r\n\t<li>Statutul de reglementare al CE-IVD permite utilizarea sistemului de testare pentru diagnosticarea clinic\u0103 \u00een \u021b\u0103rile Uniunii Europene.<\/strong><\/li>\r\n<\/ul>\r\nPrimul test din Moldova pentru m\u0103surarea concentra\u021biei de anticorpi<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>ALFA diagnostica a \u00eenceput, de asemenea, testarea pacien\u021bilor pentru a\u00a0determina\u00a0concentra\u021bia anticorpilor care leag\u0103 virusul, instrument util pentru\u00a0evaluarea gradului de activare a sistemului imun ca r\u0103spuns la prezen\u021ba virusului.<\/li>\r\n\t<li>Statutul de reglementare al CE-IVD permite utilizarea sistemului de testare pentru diagnosticarea clinic\u0103 \u00een \u021b\u0103rile Uniunii Europene.<\/strong><\/li>\r\n<\/ul>","description_clear":"Agita\u021bia pe marginea subiectului anticorpilor pe care organismul \u00eei direc\u021bioneaz\u0103 pentru lupta cu coronavirusul nu dispare - un num\u0103r tot mai mare de persoane care au fost bolnavi (\u0219i nu numai) sunt testa\u021bi pentru anticorpi, fiind motiva\u021bi de o multitudine de cauze, dar, \u00een primul r\u00e2nd, pentru a evalua imunitatea. R\u0103spund oare testele de laborator la toate \u00eentreb\u0103rile? Ast\u0103zi, c\u00e2nd au trecut mai mult de \u0219ase luni de la \u00eenceputul epidemiei, rolul anticorpilor produ\u0219i de c\u0103tre sistemul imun \u00eempotriva SARS-CoV-2 a devenit clar\u0103. S-a dovedit c\u0103 exist\u0103 diferite categorii de anticorpi.\r\n\u00a0\r\nAnticorpi care\u00a0LEAG\u0102\u00a0virusul\r\n\r\n\tAnume acest grup heterogen de anticorpi, este testat, ast\u0103zi, pe scar\u0103 larg\u0103 \u00een laboratoarele medicale.\r\n\r\n\u00centruc\u00e2t ace\u0219ti anticorpi sunt direc\u021biona\u021bi \u00eempotriva diferitelor proteine \u200b\u200breceptor (N, S) ale virusului, detectarea lor indic\u0103, \u00een primul r\u00e2nd, contactul persoanei cu virusul, \u00een al doilea r\u00e2nd, ajut\u0103 medicii s\u0103 evalueze mai exact momentul infect\u0103rii \u0219i faza procesului. Func\u021bia de asigurare a imunit\u0103\u021bii \u00een cazul anticorpii care leag\u0103 virusul este absent\u0103, iar plasma celor care s-au recuperat de COVID-19 \u0219i care con\u021bin ace\u0219ti anticorpi este poten\u021bial ineficient\u0103.\r\n\u00a0\r\nAnticorpi care\u00a0NEUTRALIZEAZ\u0102\u00a0virusul\r\n\r\n\r\n\tTradi\u021bional, ace\u0219ti anticorpi sunt determina\u021bi numai \u00een laboratoare ultra specializate, echipate s\u0103 lucreze cu viru\u0219i \u0219i culturi vii, iar tehnologia \u00een sine este biologic periculoas\u0103 \u0219i nu se aplic\u0103 pentru practica clinic\u0103 de rutin\u0103.\r\n\r\nAcest tip de anticorpi este singurul care are func\u021bia de a bloca legarea SARS-CoV-2 cu receptorul ACE (enzima de conversie a angiotensinei) pe suprafa\u021ba celulei umane, ceea ce \u00eenseamn\u0103 c\u0103 previne p\u0103trunderea virusului \u00een celul\u0103 \u0219i respectiv, dezvoltarea bolii. De fapt, ace\u0219ti anticorpi neutralizeaz\u0103 activitatea virusului \u0219i formeaz\u0103 imunitate, iar plasma donatoare care le con\u021bine are poten\u021bial terapeutic. Prin urmare, cel mai important, stimularea sistemului imun pentru a produce anticorpi neutralizan\u021bi este scopul final al vaccin\u0103rii pentru a preveni COVID-19.\r\n\u00a0\r\nTestele de laborator disponibile \u00een comer\u021b nu pot face diferen\u021ba \u00eentre anticorpii neutralizan\u021bi \u0219i anticorpii de legare.\r\n\u00a0\r\nPrimul test din lume pentru detectarea anticorpilor neutralizan\u021bi\r\n\r\n\r\n\tALFA diagnostica, unul dintre primii din Europa, care a \u00eenceput determinarea de laborator a anticorpilor\u00a0cu\u00a0func\u021bie de neutralizare\u00a0utiliz\u00e2nd o tehnologie brevetat\u0103, implementat\u0103 \u00eentr-o platform\u0103 pentru imunoanaliz\u0103 de rutin\u0103 \u0219i, cel mai important, f\u0103r\u0103 a fi nevoie s\u0103 se utilizeze materiale biologice vii \u0219i echipamente de protec\u021bie special\u0103. Rezultatele testului coreleaz\u0103 perfect cu rezultatele ob\u021binute prin testul clasic de neutralizare pe culturi vii infectate cu SARS-CoV-2.\r\n\tLa baza primul test func\u021bional din lume, st\u0103 imitarea interac\u021biunii unui virus surogat recombinant (S1-RBD) cu un receptor de celule recombinante (ACE). La prezen\u021ba anticorpilor neutralizan\u021bi \u00een proba pacientului, legarea S1-RBD \u0219i ACE este blocat\u0103 (nu se produce nicio reac\u021bie \u00eentre ei) \u0219i invers, care este detectat\u0103 \u00een mod clar de sistemul de testare.\r\n\tUn rezultat pozitiv al testului indic\u0103 faptul c\u0103 pacientul are anticorpi eficien\u021bi care pot neutraliza activitatea virusului, ceea ce este o dovad\u0103 a prezen\u021bei imunit\u0103\u021bii \u00een perioada de timp curent\u0103. Trebuie de subliniat faptul c\u0103, detectarea anticorpilor neutralizan\u021bi nu \u00eenseamn\u0103 c\u0103 m\u0103surile individuale de prevenire a infec\u021biei pot fi ignorate.\r\n\tStatutul de reglementare al CE-IVD permite utilizarea sistemului de testare pentru diagnosticarea clinic\u0103 \u00een \u021b\u0103rile Uniunii Europene.\r\n\r\nPrimul test din Moldova pentru m\u0103surarea concentra\u021biei de anticorpi\r\n\r\n\r\n\tALFA diagnostica a \u00eenceput, de asemenea, testarea pacien\u021bilor pentru a\u00a0determina\u00a0concentra\u021bia anticorpilor care leag\u0103 virusul, instrument util pentru\u00a0evaluarea gradului de activare a sistemului imun ca r\u0103spuns la prezen\u021ba virusului.\r\n\tStatutul de reglementare al CE-IVD permite utilizarea sistemului de testare pentru diagnosticarea clinic\u0103 \u00een \u021b\u0103rile Uniunii Europene.","keymeta":"","descriptionmeta":"","shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/412\/1","url":"\/ro\/magazine\/primul-test-din-lume-pentru-detectarea-anticorpilor-neutralizanti-sars-cov-2-412","url_full":"https:\/\/alfalab.md\/ro\/magazine\/primul-test-din-lume-pentru-detectarea-anticorpilor-neutralizanti-sars-cov-2-412","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/primul-test-din-lume-pentru-detectarea-anticorpilor-neutralizanti-sars-cov-2-412","show_startdate_d":"","show_enddate_d":"","date_d":"2020-09-28","show_startdate_text":"","show_enddate_text":"","date_text":"2020-09-28","date_day":"28","date_month":"Septembrie","date_published":"2018-06-04","date_modify":"2018-06-04","image_id":"129","image_ids":["129"],"image_url":"\/files\/getfile\/129\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/129\/","activegallery":[{"id":"249","parentclass":"magazine","idparentclass":"412","order":"1","idfile":"129","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/129\/","name":"59.jpg"}],"activeattachments":[],"activevideos":[{"id":"14","parentclass":"magazine","idparentclass":"412","order":"0","idvideoitem":"23","status":"1","name":"Sia - Move Your Body (Remix 2018)","video_host":"youtube","video_videoid":"1kfUnvvRvMM","video_name":"Sia - Move Your Body (Remix 2018)","video_video_img":"https:\/\/img.youtube.com\/vi\/1kfUnvvRvMM\/mqdefault.jpg?","video_location":"https:\/\/www.youtube.com\/watch?v=1kfUnvvRvMM"}],"videoobj":{"id":"14","parentclass":"magazine","idparentclass":"412","order":"0","idvideoitem":"23","status":"1","name":"Sia - Move Your Body (Remix 2018)","video_host":"youtube","video_videoid":"1kfUnvvRvMM","video_name":"Sia - Move Your Body (Remix 2018)","video_video_img":"https:\/\/img.youtube.com\/vi\/1kfUnvvRvMM\/mqdefault.jpg?","video_location":"https:\/\/www.youtube.com\/watch?v=1kfUnvvRvMM"}},{"id":"456","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1589706000","views":null,"showonhome":"1","magazinetype":"2","name":"Cum s\u0103 interpret\u0103m corect rezultatele testelor pentru COVID-19?","author":"author blog meta","info":null,"title":"Cum s\u0103 interpret\u0103m corect rezultatele testelor pentru COVID-19?","urlsuffix":null,"description":"Epidemia actual\u0103 a provocat un interes deosebit pentru \u00a0oamenii de \u0219tiin\u021b\u0103, medici \u0219i pacien\u021bi \u00een\u0219i\u0219i \u00een cercetarea de laborator infec\u021bii noi. Din motive evidente, majoritatea \u00eentreb\u0103rilor sunt adresate speciali\u0219tilor \u00een medicin\u0103 de laborator,dintre care cele mai importante sunt - precizia \u0219i fiabilitatea, interpretarea \u0219i valoarea prognostic\u0103 a testelor pentru COVID-19. \r\n \r\nDatorit\u0103 num\u0103rului mare de astfel de solicit\u0103ri din partea medicilor, ALFA diagnostica, pe baza unei analize a datelor din lumea actual\u0103, \u0219i-a prezentat propria revizuire sub form\u0103 de \u00eentreb\u0103ri \u0219i r\u0103spunsuri, \u0219i anume: cum s\u0103 utiliza\u021bi \u0219i s\u0103 interpreta\u021bi corect rezultatele testelor pentru diagnosticul de COVID-19.<\/strong> \r\n \r\nCOVID-19<\/strong><\/span>\r\n<ul>\r\n\t<li>CO<\/strong>ronaVI<\/strong>rus\u00a0D<\/strong>isease sau boala, cauzat\u0103 de coronavirus SARS-CoV-2.<\/li>\r\n<\/ul>\r\nCe teste sunt folosite pentru stabilirea diagnosticului\u2013 COVID-19?<\/strong><\/span> \r\nTeste de detectare\r\n<ul>\r\n\t<li>Virusul \u00een sine (izolarea virusului) \u2013 \u00een practica de rutin\u0103 nu se aplic\u0103.<\/li>\r\n\t<li>Componenta proteic\u0103 a virusului (antigen) \u2013 imunocromatografie (teste-rapide).<\/li>\r\n\t<li>Fragmentul ARN al virusului \u2013 reac\u021bia de polimeraz\u0103 \u00een lan\u021b (PCR).<\/li>\r\n\t<li>ARN- ul virusului \u2013 secven\u021bierea \u00a0urm\u0103toarei genera\u021bii NGS).<\/li>\r\n<\/ul>\r\nCele mai des sunt utilizate testele de reac\u021bie ale polimerazei \u00een lan\u021b (PCR).<\/strong><\/span> \r\nCare sunt avantajele testelor PCR?\r\n<ul>\r\n\t<li>Sensibilitate \u00eenalt\u0103.<\/li>\r\n\t<li>Specificitate \u00eenalt\u0103.<\/li>\r\n\t<li>Rata acceptabil\u0103 de ob\u021binere a rezultatelor (de obicei 1-2 zile lucr\u0103toare).<\/li>\r\n<\/ul>\r\nCe influen\u021beaz\u0103 precizia \u0219i fiabilitatea test\u0103rii PCR?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Perioada de prelevare a probei<\/strong>\u00a0(testare prea devreme sau t\u00e2rzie)<\/li>\r\n<\/ul>\r\nARN SARS-CoV-2 este detectat \u00a0\u00een tractul respirator superior la majoritatea pacien\u021bilor cu aproximativ 48 de ore \u00eenainte de debutul simptomelor \u0219i cu \u00eenc\u0103 2 s\u0103pt\u0103m\u00e2ni dup\u0103 debutul simptomelor \u0219i aproximativ 3 s\u0103pt\u0103m\u00e2ni \u00een tractul respirator inferior, dup\u0103 care, de regul\u0103, \u00eenceteaz\u0103 s\u0103 mai fie detectat. Uneori ARN-ul SARS-CoV-2 poate continua s\u0103 fie detectat la 4-5-6 s\u0103pt\u0103m\u00e2ni de la debutul simptomelor (cauze posibilele - eroare \u00een testare, reinfectare, reactivare).\r\n\r\n<ul>\r\n\t<li>Locul prelev\u0103rii probei<\/strong><\/li>\r\n<\/ul>\r\nTrebuie remarcat faptul c\u0103 cel mai adesea ARN SARS-CoV-2 se g\u0103se\u0219te \u00een lavajul din arborele bronhoalveolare (93%), mai rar \u00een sput\u0103 (72%), \u00een nas (63%) \u0219i \u00een materiile fecale (57%) \u0219i mult mai rar \u00een faringe (32%) din cazuri.\r\n\r\n<ul>\r\n\t<li>Calitatea colect\u0103rii biomaterialului<\/strong><\/li>\r\n<\/ul>\r\nDepinde de tehnologie \u0219i consumabile utilizate. Tehnica slab\u0103 de c\u0103tre personalul medical sau de a ob\u021bine o prob\u0103 \u00a0de c\u0103tre pacient \u00eensu\u0219i este motivul cel mai frecvent pentru eficien\u021ba sc\u0103zut\u0103 a cercet\u0103rii.\r\n\r\n<ul>\r\n\t<li>Caracteristicile sistemului de testare utilizat (reagen\u021bi)<\/strong><\/li>\r\n<\/ul>\r\nCcaracteristicile importante sunt: num\u0103rul de ARN-uri specifice detectate (> 2) \u0219i pragul de detec\u021bie (<500 copii de ARN \/ ml). \r\n \r\nOricare dintre factorii \u0219i combina\u021biile lor poate duce la rezultate fals negative (rezultatul testului negativ \u00een prezen\u021ba virusului).<\/em> \r\n \r\nDac\u0103 rezultatul testului PCR este pozitiv?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Detectarea (pozitivitatea) ARN SARS-CoV-2 \u00een prob\u0103 este considerat\u0103 a fi un criteriu suficient pentru stabilirea unui diagnostic de COVID-19 \u00een contextul istoricului medical \u0219i al istoricului epidemiologic al pacientului.<\/li>\r\n<\/ul>\r\nNot\u0103:<\/em>\r\n\r\n<ul>\r\n\t<li>Detectarea ARN-ului SARS-CoV-2 poate s\u0103 nu fie un criteriu pentru viabilitatea virusului sau c\u0103, SARS-CoV-2 este cauza apari\u021biei simptomelor clinice (pentru a exclude o infec\u021bie concomitent\u0103, este util s\u0103 se efectueze diagnosticarea PCR a\u00a0gripei \u0219i a virusului sinci\u021bial respirator.<\/li>\r\n\t<li>\u00cen primul r\u00e2nd, \u00een dinamic\u0103, pozitivitatea scade \u0219i dispare la probele din nazofaringe, apoi la probele din sput\u0103 \u0219i, \u00een sf\u00e2r\u0219it, ob\u021binute din probele lavajului bronheoalveolar.<\/li>\r\n\t<li>\u00cenc\u0103rcarea viral\u0103 la pacien\u021bii asimptomatici este similar\u0103 cu cea la pacien\u021bii simptomatici, ceea ce indic\u0103 o poten\u021bial\u0103 transmitere a pacien\u021bilor asimptomatici sau minim simptomatici.<\/li>\r\n\t<li>Virusul \u00eenceteaz\u0103 s\u0103 mai fie detectat prin metode virusologice la aproximativ 10 zile de la debutul simptomelor.<\/li>\r\n<\/ul>\r\nDac\u0103 rezultatul testului PCR este negativ?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Absen\u021ba (negativitatea) ARN SARS-CoV-2 \u00een prob\u0103 este considerat\u0103 un criteriu suficient pentru a exclude infec\u021bia SARS-CoV-2 actual\u0103 \u00een contextul istoricului medical \u0219i al istoricului epidemiologic al pacientului.<\/li>\r\n<\/ul>\r\nNot\u0103:<\/em>\r\n\r\n<ul>\r\n\t<li>Rezultat negativ al testului indic\u0103 faptul c\u0103 ARN-ul SARS-CoV-2 nu a fost prezent \u00een proba de test peste limita de detectare \u0219i \/ sau inhibitori de PCR au fost prezen\u021bi \u00een prob\u0103.<\/li>\r\n\t<li>Un rezultat negativ nu poate exclude complet infec\u021bia cu SARS-CoV-2 19, mai ales dac\u0103 a fost investigat biomaterialul ob\u021binut din nazofaringe \u0219i \/ sau \u00eentr-un stadiu incipient al bolii.<\/li>\r\n\t<li>Dac\u0103 rezultatul este negativ, dar suspiciunea de COVID-19 r\u0103m\u00e2ne, este necesar s\u0103 se efectueze un nou test PCR din acela\u0219i biomaterial sau alt biomaterial, dar cu o sarcin\u0103 viral\u0103 poten\u021bial mai mare (sput\u0103 sau tampoane ob\u021binute prin lavaj bronheoalveolar) \u0219i \/ sau determinare serologic\u0103 a anticorpilor, \u00een primul r\u00e2nd IgM.<\/li>\r\n<\/ul>\r\nCu ce scop se aplic\u0103 testarea anticorpilor la COVID-19?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Evaluarea r\u0103spunsului imun adaptativ al organismului la SARS-CoV-2 pentru a sus\u021bine luarea empiric\u0103 a deciziilor clinice \u00een diagnosticul \u0219i managementul pacien\u021bilor cu COVID-19.<\/li>\r\n\t<li>Identificarea persoanelor asimptomatice sau a pacien\u021bilor cu rezultate negative ale PCR cauzate unei \u00eenc\u0103rc\u0103turi virale foarte sc\u0103zute \u0219i incapacit\u0103\u021bii de a realiza cercetarea biomaterial din tractul respirator inferior.<\/li>\r\n\t<li>Evaluarea st\u0103rii imunologice (imunitate) la pacien\u021bii care au suportat aceast\u0103 boal\u0103. Dup\u0103 dezvoltarea unui vaccin \u00eempotriva COVID-19, persoanele care nu au imunitate la SARS-CoV-2, conform unui studiu privind anticorpii, pot deveni o prioritate pentru vaccinare.<\/li>\r\n\t<li>Evaluarea epidemiologic\u0103 a nivelului de infectare a popula\u021biei SARS-CoV-2.<\/li>\r\n\t<li>Identificarea \/ screening-ul poten\u021bialilor donatori de plasm\u0103 extrem de reactivi (reconvalescen\u021bi COVID-19).<\/li>\r\n<\/ul>\r\nAr trebui s\u0103 utiliza\u021bi teste la anticorpi pentru a stabili un diagnostic COVID-19?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Testele anticorpilor nu sunt destinate s\u0103 confirme sau s\u0103 exclud\u0103 o infec\u021bie actual\u0103 cu SARS-CoV-2.<\/li>\r\n<\/ul>\r\nCe teste trebuie utilizate pentru a evalua un r\u0103spuns imun adaptativ la SARS-CoV-2?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Testele care detecteaz\u0103 anticorpi (imunoglobuline) din clasele\u00a0IgM,\u00a0IgG, IgA \u00eempotriva antigenelor virusului.<\/li>\r\n<\/ul>\r\nCe metode sunt utilizate pentru a detecta anticorpi \u00eempotriva SARS-CoV-2?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Analiza imunocromatografic\u0103 (implementat\u0103 \u00een sisteme de testare rapid\u0103, multe dintre ele av\u00e2nd caracteristici de diagnostic sc\u0103zute (sau discutabile).<\/li>\r\n\t<li>Analiza chemiluminescent\u0103 (necesit\u0103 echipamente analitice speciale, fiabilitate \u0219i costuri ridicate).<\/li>\r\n\t<li>Analiza imunoenzimelor (fiabilitate ridicat\u0103, cost rezonabil).<\/li>\r\n\t<li>Cel mai adesea, sunt utilizate teste bazate pe testul imunoenzimatic (ELISA).<\/li>\r\n<\/ul>\r\nCare pot fi rezultatele unui test serologic pentru anticorpi?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Pozitiv (reactiv), negativ (non-reactiv), valoare limitrof\u0103*.<\/li>\r\n<\/ul>\r\n*Valoare limitrof\u0103, care nu permite de a atribui veridic (\u0441u o probabilitate > 95%) un rezultat pozitiv sau negativ. Se recomand\u0103 testare de laborator repetat\u0103 peste 10-14 zile.<\/em> \r\n \r\nDac\u0103 rezultatul testului la anticorpi IgG este pozitiv?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Infec\u021bie anterioar\u0103 sau continu\u0103.<\/li>\r\n<\/ul>\r\nNot\u0103:<\/em>\r\n\r\n<ul>\r\n\t<li>Pentru a atinge niveluri de IgG detectabile, este necesar\u0103 o medie de 10-14 zile dup\u0103 debutul simptomelor (\u00een func\u021bie de caracteristicile individuale, \u00eenc\u0103rc\u0103tura viral\u0103 etc.).<\/li>\r\n\t<li>Concentra\u021bia maxim\u0103 a anticorpilor este \u00eenregistrat\u0103 la 20 de zile de la debutul simptomelor.<\/li>\r\n\t<li>Momentul circula\u021biei IgG \u00een s\u00e2nge nu este cunoscut \u00een prezent din motive obiective.<\/li>\r\n\t<li>Unele persoane nu genereaz\u0103 IgG din cauza imunosupresiei \u0219i \/ sau a altor cauze.<\/li>\r\n\t<li>Rela\u021bia dintre pozitivitatea IgG \u0219i imunitatea la SARS-CoV-2 nu a fost \u00eenc\u0103 stabilit\u0103.<\/li>\r\n\t<li>Sistemele de testare care utilizeaz\u0103 antigeni N (Nucleocapsid) \u0219i S (Spike) ca faz\u0103 solid\u0103 demonstreaz\u0103 o sensibilitate mai bun\u0103 dec\u00e2t sistemele de testare folosind doar unul dintre antigeni.<\/li>\r\n<\/ul>\r\nDac\u0103 rezultatul testului la anticorpi IgG este negativ?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Anticorpii IgG \u00eempotriva SARS-CoV-2 nu sunt prezen\u021bi la un nivel care poate fi detectat de sistemul de imunoanaliz\u0103.<\/li>\r\n\t<li>Testarea este efectuat\u0103 \u00eentr-un timp scurt.<\/li>\r\n\t<li>Nu este exclus\u0103 infec\u021bia, \u00een special persoanele care au avut contact cu alte persoane SARS-CoV-2 infectate.<\/li>\r\n<\/ul>\r\nDac\u0103 rezultatul testului la anticorpi IgG este la pragul limit\u0103?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Anticorpii IgG \u00eempotriva SARS-CoV-2 sunt prezen\u021bi sau aproape de pragul limit\u0103 de detec\u021bie de c\u0103tre sistemul pentru imunoanaliz\u0103.<\/li>\r\n\t<li>Testarea repetat\u0103 peste 1-2 s\u0103pt\u0103m\u00e2ni.<\/li>\r\n<\/ul>\r\nDac\u0103 rezultatul testului la anticorpii IgM \u0219i \/ sau IgA este pozitiv?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Replicarea activ\u0103 (reproducerea) virusului la momentul actual.<\/li>\r\n<\/ul>\r\nNot\u0103:<\/em>\r\n\r\n<ul>\r\n\t<li>Pentru a atinge niveluri detectabile de IgM \/ A, este necesar\u0103 o medie de 3-6 zile dup\u0103 debutul simptomelor (\u00een func\u021bie de caracteristicile individuale, \u00eenc\u0103rc\u0103tura viral\u0103 etc.).<\/li>\r\n\t<li>Concentra\u021bia maxim\u0103 a anticorpilor este \u00eenregistrat\u0103 peste 5-12 de zile de la debutul simptomelor.<\/li>\r\n\t<li>Timpul de circula\u021bie IgM\/A \u00een s\u00e2nge este de aproximativ 3 s\u0103pt\u0103m\u00e2ni, nefiind complet stabilit.<\/li>\r\n\t<li>Unele persoane nu genereaz\u0103 IgM\/A din cauza imunosupresiei \u0219i \/ sau a altor cauze.<\/li>\r\n\t<li>Cea mai \u00a0bun\u0103 sensibilitate o demonstreaz\u0103 sistemul de testare , \u00een primul r\u00e2nd, determin\u00e2nd anticorpii A \u0219i M total \u0219i, \u00een al doilea r\u00e2nd, folosind antigeni N (Nucleocapsid) \u0219i S (Spike) ca faz\u0103 solid\u0103, dec\u00e2t sistemele de testare folosind doar unul dintre antigeni.<\/li>\r\n\t<li>Sensibilitatea de detectare a IgM este mai mare dec\u00e2t sensibilitatea de detec\u021bie a ARN SARS-CoV-2 peste 5-6 zile de la debutul simptomelor.<\/li>\r\n<\/ul>\r\nDac\u0103 rezultatul testului la anticorpii IgM \u0219i \/ sau IgA este negativ?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Anticorpii IgM\/A \u00eempotriva SARS-CoV-2 nu sunt prezen\u021bi la un nivel care poate fi detectat de sistemul de imunoanaliz\u0103.<\/li>\r\n\t<li>Testarea este efectuat\u0103 \u00eentr-un timp scurt.<\/li>\r\n\t<li>Nu este exclus\u0103 infec\u021bia, \u00een special persoanele care au avut contact cu alte persoane SARS-CoV-2 infectate.<\/li>\r\n<\/ul>\r\nDac\u0103 rezultatul testului la anticorpi IgM \u0219i\/sau IgA este la pragul limit\u0103?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Anticorpii IgM \u0219i\/sau IgA \u00eempotriva SARS-CoV-2 sunt prezen\u021bi sau aproape de pragul limit\u0103 de detec\u021bie de c\u0103tre sistemul pentru imunoanaliz\u0103.<\/li>\r\n\t<li>Testarea repetat\u0103 peste 1-2 s\u0103pt\u0103m\u00e2ni.<\/li>\r\n<\/ul>\r\nExist\u0103 reactivitate \u00eencruci\u0219at\u0103 \u00eentre anticorpi \u00eempotriva SARS-CoV-2 \u0219i alte coronavirusuri?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Analiza panelurilor de probe de s\u00e2nge prelevate \u00een 2010, 2017 \u0219i 2019 arat\u0103 c\u0103, \u00een cazuri foarte rare (<1%), rezultatele fals-pozitive sunt posibile datorit\u0103 reac\u021biilor \u00eencruci\u0219ate cu tulpini endemice (sezoniere) de coronavirus (HKU1, NL63, OC43, 229E).<\/li>\r\n<\/ul>\r\nSe formeaz\u0103 imunitate la pacien\u021bii ce au suportat infec\u021bia?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Nu se \u0219tie, p\u00e2n\u0103 \u00een prezent nu exist\u0103 un r\u0103spuns clar la aceast\u0103 \u00eentrebare.<\/li>\r\n\t<li>\u00cen ceea ce prive\u0219te SARS-CoV, s-a demonstrat c\u0103 IgG ofer\u0103 o imunitate de p\u00e2n\u0103 la 2 ani.<\/li>\r\n<\/ul>\r\nCum se interpreteaz\u0103 corect rezultatele testelor moleculare \u0219i serologice?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Utilizarea combinat\u0103 a metodelor de diagnostic molecular \u0219i serologic \u00eembun\u0103t\u0103\u021be\u0219te semnificativ diagnosticul. Rezultatele trebuie interpretate \u00eentotdeauna \u00een contextul istoricului medical \u0219i al istoricului epidemiologic al pacientului.<\/li>\r\n<\/ul>\r\n\u00a0\r\n\r\n<table border=\"1\" cellpadding=\"0\" cellspacing=\"0\" style=\"width:700px;\" width=\"0\">\r\n\t<tbody>\r\n\t\t<tr>\r\n\t\t\t<td colspan=\"3\" style=\"width:170px;height:45px;\">Rezultatele testelor<\/strong><\/td>\r\n\t\t\t<td style=\"width:775px;height:45px;\">Raportul de laborator<\/strong><\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:57px;height:20px;\">ARN<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">IgM<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">IgG<\/td>\r\n\t\t\t<td style=\"width:775px;height:20px;\">\u00a0<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">\u2013<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">\u2013<\/td>\r\n\t\t\t<td style=\"width:775px;height:20px;\">\u00a0Etapa timpurie (ini\u021bial\u0103) a infec\u021biei.<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">\u2013<\/td>\r\n\t\t\t<td style=\"width:775px;height:20px;\">\u00a0Faza activ\u0103 a infec\u021biei.<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:775px;height:20px;\">\u00a0Faza activ\u0103 a infec\u021biei \u0219i formarea imunit\u0103\u021bii adaptive.<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">\u2013<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:775px;height:20px;\">\u00a0Etapa t\u00e2rzie a infec\u021biei.<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:57px;height:20px;\">\u2013<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">\u2013<\/td>\r\n\t\t\t<td style=\"width:775px;height:20px;\">\u00a0Etapa timpurie a infec\u021biei. Este posibil rezultatul fals-negativ al PCR.<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:57px;height:20px;\">\u2013<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">\u2013<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:775px;height:20px;\">\u00a0\u0420Reconvalescen\u021ba.<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width:57px;height:20px;\">\u2013<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:57px;height:20px;\">+<\/td>\r\n\t\t\t<td style=\"width:775px;height:20px;\">\u00a0Faza activ\u0103 a infec\u021biei. Este posibil rezultatul fals-negativ al PCR.<\/td>\r\n\t\t<\/tr>\r\n\t<\/tbody>\r\n<\/table>\r\n\u00a0 \r\n\u00a0 \r\n\u0410.\u041cereu\u021ba<\/strong> \r\n\u00a0","description_clear":"Epidemia actual\u0103 a provocat un interes deosebit pentru \u00a0oamenii de \u0219tiin\u021b\u0103, medici \u0219i pacien\u021bi \u00een\u0219i\u0219i \u00een cercetarea de laborator infec\u021bii noi. Din motive evidente, majoritatea \u00eentreb\u0103rilor sunt adresate speciali\u0219tilor \u00een medicin\u0103 de laborator,dintre care cele mai importante sunt - precizia \u0219i fiabilitatea, interpretarea \u0219i valoarea prognostic\u0103 a testelor pentru COVID-19.\r\n\r\nDatorit\u0103 num\u0103rului mare de astfel de solicit\u0103ri din partea medicilor, ALFA diagnostica, pe baza unei analize a datelor din lumea actual\u0103, \u0219i-a prezentat propria revizuire sub form\u0103 de \u00eentreb\u0103ri \u0219i r\u0103spunsuri, \u0219i anume: cum s\u0103 utiliza\u021bi \u0219i s\u0103 interpreta\u021bi corect rezultatele testelor pentru diagnosticul de COVID-19.\r\n\r\nCOVID-19\r\n\r\n\tCOronaVIrus\u00a0Disease sau boala, cauzat\u0103 de coronavirus SARS-CoV-2.\r\n\r\nCe teste sunt folosite pentru stabilirea diagnosticului\u2013 COVID-19?\r\nTeste de detectare\r\n\r\n\tVirusul \u00een sine (izolarea virusului) \u2013 \u00een practica de rutin\u0103 nu se aplic\u0103.\r\n\tComponenta proteic\u0103 a virusului (antigen) \u2013 imunocromatografie (teste-rapide).\r\n\tFragmentul ARN al virusului \u2013 reac\u021bia de polimeraz\u0103 \u00een lan\u021b (PCR).\r\n\tARN- ul virusului \u2013 secven\u021bierea \u00a0urm\u0103toarei genera\u021bii NGS).\r\n\r\nCele mai des sunt utilizate testele de reac\u021bie ale polimerazei \u00een lan\u021b (PCR).\r\nCare sunt avantajele testelor PCR?\r\n\r\n\tSensibilitate \u00eenalt\u0103.\r\n\tSpecificitate \u00eenalt\u0103.\r\n\tRata acceptabil\u0103 de ob\u021binere a rezultatelor (de obicei 1-2 zile lucr\u0103toare).\r\n\r\nCe influen\u021beaz\u0103 precizia \u0219i fiabilitatea test\u0103rii PCR?\r\n\r\n\r\n\tPerioada de prelevare a probei\u00a0(testare prea devreme sau t\u00e2rzie)\r\n\r\nARN SARS-CoV-2 este detectat \u00a0\u00een tractul respirator superior la majoritatea pacien\u021bilor cu aproximativ 48 de ore \u00eenainte de debutul simptomelor \u0219i cu \u00eenc\u0103 2 s\u0103pt\u0103m\u00e2ni dup\u0103 debutul simptomelor \u0219i aproximativ 3 s\u0103pt\u0103m\u00e2ni \u00een tractul respirator inferior, dup\u0103 care, de regul\u0103, \u00eenceteaz\u0103 s\u0103 mai fie detectat. Uneori ARN-ul SARS-CoV-2 poate continua s\u0103 fie detectat la 4-5-6 s\u0103pt\u0103m\u00e2ni de la debutul simptomelor (cauze posibilele - eroare \u00een testare, reinfectare, reactivare).\r\n\r\n\r\n\tLocul prelev\u0103rii probei\r\n\r\nTrebuie remarcat faptul c\u0103 cel mai adesea ARN SARS-CoV-2 se g\u0103se\u0219te \u00een lavajul din arborele bronhoalveolare (93%), mai rar \u00een sput\u0103 (72%), \u00een nas (63%) \u0219i \u00een materiile fecale (57%) \u0219i mult mai rar \u00een faringe (32%) din cazuri.\r\n\r\n\r\n\tCalitatea colect\u0103rii biomaterialului\r\n\r\nDepinde de tehnologie \u0219i consumabile utilizate. Tehnica slab\u0103 de c\u0103tre personalul medical sau de a ob\u021bine o prob\u0103 \u00a0de c\u0103tre pacient \u00eensu\u0219i este motivul cel mai frecvent pentru eficien\u021ba sc\u0103zut\u0103 a cercet\u0103rii.\r\n\r\n\r\n\tCaracteristicile sistemului de testare utilizat (reagen\u021bi)\r\n\r\nCcaracteristicile importante sunt: num\u0103rul de ARN-uri specifice detectate (> 2) \u0219i pragul de detec\u021bie (<500 copii de ARN \/ ml).\r\n\r\nOricare dintre factorii \u0219i combina\u021biile lor poate duce la rezultate fals negative (rezultatul testului negativ \u00een prezen\u021ba virusului).\r\n\r\nDac\u0103 rezultatul testului PCR este pozitiv?\r\n\r\n\r\n\tDetectarea (pozitivitatea) ARN SARS-CoV-2 \u00een prob\u0103 este considerat\u0103 a fi un criteriu suficient pentru stabilirea unui diagnostic de COVID-19 \u00een contextul istoricului medical \u0219i al istoricului epidemiologic al pacientului.\r\n\r\nNot\u0103:\r\n\r\n\r\n\tDetectarea ARN-ului SARS-CoV-2 poate s\u0103 nu fie un criteriu pentru viabilitatea virusului sau c\u0103, SARS-CoV-2 este cauza apari\u021biei simptomelor clinice (pentru a exclude o infec\u021bie concomitent\u0103, este util s\u0103 se efectueze diagnosticarea PCR a\u00a0gripei \u0219i a virusului sinci\u021bial respirator.\r\n\t\u00cen primul r\u00e2nd, \u00een dinamic\u0103, pozitivitatea scade \u0219i dispare la probele din nazofaringe, apoi la probele din sput\u0103 \u0219i, \u00een sf\u00e2r\u0219it, ob\u021binute din probele lavajului bronheoalveolar.\r\n\t\u00cenc\u0103rcarea viral\u0103 la pacien\u021bii asimptomatici este similar\u0103 cu cea la pacien\u021bii simptomatici, ceea ce indic\u0103 o poten\u021bial\u0103 transmitere a pacien\u021bilor asimptomatici sau minim simptomatici.\r\n\tVirusul \u00eenceteaz\u0103 s\u0103 mai fie detectat prin metode virusologice la aproximativ 10 zile de la debutul simptomelor.\r\n\r\nDac\u0103 rezultatul testului PCR este negativ?\r\n\r\n\r\n\tAbsen\u021ba (negativitatea) ARN SARS-CoV-2 \u00een prob\u0103 este considerat\u0103 un criteriu suficient pentru a exclude infec\u021bia SARS-CoV-2 actual\u0103 \u00een contextul istoricului medical \u0219i al istoricului epidemiologic al pacientului.\r\n\r\nNot\u0103:\r\n\r\n\r\n\tRezultat negativ al testului indic\u0103 faptul c\u0103 ARN-ul SARS-CoV-2 nu a fost prezent \u00een proba de test peste limita de detectare \u0219i \/ sau inhibitori de PCR au fost prezen\u021bi \u00een prob\u0103.\r\n\tUn rezultat negativ nu poate exclude complet infec\u021bia cu SARS-CoV-2 19, mai ales dac\u0103 a fost investigat biomaterialul ob\u021binut din nazofaringe \u0219i \/ sau \u00eentr-un stadiu incipient al bolii.\r\n\tDac\u0103 rezultatul este negativ, dar suspiciunea de COVID-19 r\u0103m\u00e2ne, este necesar s\u0103 se efectueze un nou test PCR din acela\u0219i biomaterial sau alt biomaterial, dar cu o sarcin\u0103 viral\u0103 poten\u021bial mai mare (sput\u0103 sau tampoane ob\u021binute prin lavaj bronheoalveolar) \u0219i \/ sau determinare serologic\u0103 a anticorpilor, \u00een primul r\u00e2nd IgM.\r\n\r\nCu ce scop se aplic\u0103 testarea anticorpilor la COVID-19?\r\n\r\n\r\n\tEvaluarea r\u0103spunsului imun adaptativ al organismului la SARS-CoV-2 pentru a sus\u021bine luarea empiric\u0103 a deciziilor clinice \u00een diagnosticul \u0219i managementul pacien\u021bilor cu COVID-19.\r\n\tIdentificarea persoanelor asimptomatice sau a pacien\u021bilor cu rezultate negative ale PCR cauzate unei \u00eenc\u0103rc\u0103turi virale foarte sc\u0103zute \u0219i incapacit\u0103\u021bii de a realiza cercetarea biomaterial din tractul respirator inferior.\r\n\tEvaluarea st\u0103rii imunologice (imunitate) la pacien\u021bii care au suportat aceast\u0103 boal\u0103. Dup\u0103 dezvoltarea unui vaccin \u00eempotriva COVID-19, persoanele care nu au imunitate la SARS-CoV-2, conform unui studiu privind anticorpii, pot deveni o prioritate pentru vaccinare.\r\n\tEvaluarea epidemiologic\u0103 a nivelului de infectare a popula\u021biei SARS-CoV-2.\r\n\tIdentificarea \/ screening-ul poten\u021bialilor donatori de plasm\u0103 extrem de reactivi (reconvalescen\u021bi COVID-19).\r\n\r\nAr trebui s\u0103 utiliza\u021bi teste la anticorpi pentru a stabili un diagnostic COVID-19?\r\n\r\n\r\n\tTestele anticorpilor nu sunt destinate s\u0103 confirme sau s\u0103 exclud\u0103 o infec\u021bie actual\u0103 cu SARS-CoV-2.\r\n\r\nCe teste trebuie utilizate pentru a evalua un r\u0103spuns imun adaptativ la SARS-CoV-2?\r\n\r\n\r\n\tTestele care detecteaz\u0103 anticorpi (imunoglobuline) din clasele\u00a0IgM,\u00a0IgG, IgA \u00eempotriva antigenelor virusului.\r\n\r\nCe metode sunt utilizate pentru a detecta anticorpi \u00eempotriva SARS-CoV-2?\r\n\r\n\r\n\tAnaliza imunocromatografic\u0103 (implementat\u0103 \u00een sisteme de testare rapid\u0103, multe dintre ele av\u00e2nd caracteristici de diagnostic sc\u0103zute (sau discutabile).\r\n\tAnaliza chemiluminescent\u0103 (necesit\u0103 echipamente analitice speciale, fiabilitate \u0219i costuri ridicate).\r\n\tAnaliza imunoenzimelor (fiabilitate ridicat\u0103, cost rezonabil).\r\n\tCel mai adesea, sunt utilizate teste bazate pe testul imunoenzimatic (ELISA).\r\n\r\nCare pot fi rezultatele unui test serologic pentru anticorpi?\r\n\r\n\r\n\tPozitiv (reactiv), negativ (non-reactiv), valoare limitrof\u0103*.\r\n\r\n*Valoare limitrof\u0103, care nu permite de a atribui veridic (\u0441u o probabilitate > 95%) un rezultat pozitiv sau negativ. Se recomand\u0103 testare de laborator repetat\u0103 peste 10-14 zile.\r\n\r\nDac\u0103 rezultatul testului la anticorpi IgG este pozitiv?\r\n\r\n\r\n\tInfec\u021bie anterioar\u0103 sau continu\u0103.\r\n\r\nNot\u0103:\r\n\r\n\r\n\tPentru a atinge niveluri de IgG detectabile, este necesar\u0103 o medie de 10-14 zile dup\u0103 debutul simptomelor (\u00een func\u021bie de caracteristicile individuale, \u00eenc\u0103rc\u0103tura viral\u0103 etc.).\r\n\tConcentra\u021bia maxim\u0103 a anticorpilor este \u00eenregistrat\u0103 la 20 de zile de la debutul simptomelor.\r\n\tMomentul circula\u021biei IgG \u00een s\u00e2nge nu este cunoscut \u00een prezent din motive obiective.\r\n\tUnele persoane nu genereaz\u0103 IgG din cauza imunosupresiei \u0219i \/ sau a altor cauze.\r\n\tRela\u021bia dintre pozitivitatea IgG \u0219i imunitatea la SARS-CoV-2 nu a fost \u00eenc\u0103 stabilit\u0103.\r\n\tSistemele de testare care utilizeaz\u0103 antigeni N (Nucleocapsid) \u0219i S (Spike) ca faz\u0103 solid\u0103 demonstreaz\u0103 o sensibilitate mai bun\u0103 dec\u00e2t sistemele de testare folosind doar unul dintre antigeni.\r\n\r\nDac\u0103 rezultatul testului la anticorpi IgG este negativ?\r\n\r\n\r\n\tAnticorpii IgG \u00eempotriva SARS-CoV-2 nu sunt prezen\u021bi la un nivel care poate fi detectat de sistemul de imunoanaliz\u0103.\r\n\tTestarea este efectuat\u0103 \u00eentr-un timp scurt.\r\n\tNu este exclus\u0103 infec\u021bia, \u00een special persoanele care au avut contact cu alte persoane SARS-CoV-2 infectate.\r\n\r\nDac\u0103 rezultatul testului la anticorpi IgG este la pragul limit\u0103?\r\n\r\n\r\n\tAnticorpii IgG \u00eempotriva SARS-CoV-2 sunt prezen\u021bi sau aproape de pragul limit\u0103 de detec\u021bie de c\u0103tre sistemul pentru imunoanaliz\u0103.\r\n\tTestarea repetat\u0103 peste 1-2 s\u0103pt\u0103m\u00e2ni.\r\n\r\nDac\u0103 rezultatul testului la anticorpii IgM \u0219i \/ sau IgA este pozitiv?\r\n\r\n\r\n\tReplicarea activ\u0103 (reproducerea) virusului la momentul actual.\r\n\r\nNot\u0103:\r\n\r\n\r\n\tPentru a atinge niveluri detectabile de IgM \/ A, este necesar\u0103 o medie de 3-6 zile dup\u0103 debutul simptomelor (\u00een func\u021bie de caracteristicile individuale, \u00eenc\u0103rc\u0103tura viral\u0103 etc.).\r\n\tConcentra\u021bia maxim\u0103 a anticorpilor este \u00eenregistrat\u0103 peste 5-12 de zile de la debutul simptomelor.\r\n\tTimpul de circula\u021bie IgM\/A \u00een s\u00e2nge este de aproximativ 3 s\u0103pt\u0103m\u00e2ni, nefiind complet stabilit.\r\n\tUnele persoane nu genereaz\u0103 IgM\/A din cauza imunosupresiei \u0219i \/ sau a altor cauze.\r\n\tCea mai \u00a0bun\u0103 sensibilitate o demonstreaz\u0103 sistemul de testare , \u00een primul r\u00e2nd, determin\u00e2nd anticorpii A \u0219i M total \u0219i, \u00een al doilea r\u00e2nd, folosind antigeni N (Nucleocapsid) \u0219i S (Spike) ca faz\u0103 solid\u0103, dec\u00e2t sistemele de testare folosind doar unul dintre antigeni.\r\n\tSensibilitatea de detectare a IgM este mai mare dec\u00e2t sensibilitatea de detec\u021bie a ARN SARS-CoV-2 peste 5-6 zile de la debutul simptomelor.\r\n\r\nDac\u0103 rezultatul testului la anticorpii IgM \u0219i \/ sau IgA este negativ?\r\n\r\n\r\n\tAnticorpii IgM\/A \u00eempotriva SARS-CoV-2 nu sunt prezen\u021bi la un nivel care poate fi detectat de sistemul de imunoanaliz\u0103.\r\n\tTestarea este efectuat\u0103 \u00eentr-un timp scurt.\r\n\tNu este exclus\u0103 infec\u021bia, \u00een special persoanele care au avut contact cu alte persoane SARS-CoV-2 infectate.\r\n\r\nDac\u0103 rezultatul testului la anticorpi IgM \u0219i\/sau IgA este la pragul limit\u0103?\r\n\r\n\r\n\tAnticorpii IgM \u0219i\/sau IgA \u00eempotriva SARS-CoV-2 sunt prezen\u021bi sau aproape de pragul limit\u0103 de detec\u021bie de c\u0103tre sistemul pentru imunoanaliz\u0103.\r\n\tTestarea repetat\u0103 peste 1-2 s\u0103pt\u0103m\u00e2ni.\r\n\r\nExist\u0103 reactivitate \u00eencruci\u0219at\u0103 \u00eentre anticorpi \u00eempotriva SARS-CoV-2 \u0219i alte coronavirusuri?\r\n\r\n\r\n\tAnaliza panelurilor de probe de s\u00e2nge prelevate \u00een 2010, 2017 \u0219i 2019 arat\u0103 c\u0103, \u00een cazuri foarte rare (<1%), rezultatele fals-pozitive sunt posibile datorit\u0103 reac\u021biilor \u00eencruci\u0219ate cu tulpini endemice (sezoniere) de coronavirus (HKU1, NL63, OC43, 229E).\r\n\r\nSe formeaz\u0103 imunitate la pacien\u021bii ce au suportat infec\u021bia?\r\n\r\n\r\n\tNu se \u0219tie, p\u00e2n\u0103 \u00een prezent nu exist\u0103 un r\u0103spuns clar la aceast\u0103 \u00eentrebare.\r\n\t\u00cen ceea ce prive\u0219te SARS-CoV, s-a demonstrat c\u0103 IgG ofer\u0103 o imunitate de p\u00e2n\u0103 la 2 ani.\r\n\r\nCum se interpreteaz\u0103 corect rezultatele testelor moleculare \u0219i serologice?\r\n\r\n\r\n\tUtilizarea combinat\u0103 a metodelor de diagnostic molecular \u0219i serologic \u00eembun\u0103t\u0103\u021be\u0219te semnificativ diagnosticul. Rezultatele trebuie interpretate \u00eentotdeauna \u00een contextul istoricului medical \u0219i al istoricului epidemiologic al pacientului.\r\n\r\n\u00a0\r\n\r\n\r\n\t\r\n\t\t\r\n\t\t\tRezultatele testelor\r\n\t\t\tRaportul de laborator\r\n\t\t\r\n\t\t\r\n\t\t\tARN\r\n\t\t\tIgM\r\n\t\t\tIgG\r\n\t\t\t\u00a0\r\n\t\t\r\n\t\t\r\n\t\t\t+\r\n\t\t\t\u2013\r\n\t\t\t\u2013\r\n\t\t\t\u00a0Etapa timpurie (ini\u021bial\u0103) a infec\u021biei.\r\n\t\t\r\n\t\t\r\n\t\t\t+\r\n\t\t\t+\r\n\t\t\t\u2013\r\n\t\t\t\u00a0Faza activ\u0103 a infec\u021biei.\r\n\t\t\r\n\t\t\r\n\t\t\t+\r\n\t\t\t+\r\n\t\t\t+\r\n\t\t\t\u00a0Faza activ\u0103 a infec\u021biei \u0219i formarea imunit\u0103\u021bii adaptive.\r\n\t\t\r\n\t\t\r\n\t\t\t+\r\n\t\t\t\u2013\r\n\t\t\t+\r\n\t\t\t\u00a0Etapa t\u00e2rzie a infec\u021biei.\r\n\t\t\r\n\t\t\r\n\t\t\t\u2013\r\n\t\t\t+\r\n\t\t\t\u2013\r\n\t\t\t\u00a0Etapa timpurie a infec\u021biei. Este posibil rezultatul fals-negativ al PCR.\r\n\t\t\r\n\t\t\r\n\t\t\t\u2013\r\n\t\t\t\u2013\r\n\t\t\t+\r\n\t\t\t\u00a0\u0420Reconvalescen\u021ba.\r\n\t\t\r\n\t\t\r\n\t\t\t\u2013\r\n\t\t\t+\r\n\t\t\t+\r\n\t\t\t\u00a0Faza activ\u0103 a infec\u021biei. Este posibil rezultatul fals-negativ al PCR.\r\n\t\t\r\n\t\r\n\r\n\u00a0\r\n\u00a0\r\n\u0410.\u041cereu\u021ba\r\n\u00a0","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/456\/1","url":"\/ro\/magazine\/cum-sa-interpretam-corect-rezultatele-testelor-pentru-covid-19-456","url_full":"https:\/\/alfalab.md\/ro\/magazine\/cum-sa-interpretam-corect-rezultatele-testelor-pentru-covid-19-456","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/cum-sa-interpretam-corect-rezultatele-testelor-pentru-covid-19-456","show_startdate_d":"","show_enddate_d":"","date_d":"2020-05-17","show_startdate_text":"","show_enddate_text":"","date_text":"2020-05-17","date_day":"17","date_month":"Mai","date_published":"2021-11-18","date_modify":"2021-11-18","image_id":"197","image_ids":["197"],"image_url":"\/files\/getfile\/197\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/197\/","activegallery":[{"id":"248","parentclass":"magazine","idparentclass":"456","order":"1","idfile":"197","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/197\/","name":"58.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"455","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1588237200","views":null,"showonhome":"1","magazinetype":"2","name":"Anticorpi c\u0103tre COVID-19","author":"author blog meta","info":null,"title":"Anticorpi c\u0103tre COVID-19","urlsuffix":null,"description":"De la\u00a04<\/span><\/strong> mai ALFA diagnostica anun\u021b\u0103 \u00eenceperea test\u0103rii pacien\u021bilor pentru prezen\u021ba anticorpilor la SARS-CoV-2 (COVID-19) prin metoda imunologic\u0103. Va fi apreciat\u0103 prezen\u021ba a dou\u0103 clase principale de anticorpii - IgM \u0219i IgG. \r\n\u00a0 \r\nSubiectul anticorpilor SARS-CoV-2 este extrem de discutat \u0219i actual. Sunt multe \u00eentreb\u0103ri, la o bun\u0103 parte din care, este dificil sau chiar imposibil de r\u0103spuns, datorit\u0103 perioadei de timp destul de scurte care a trecut de la \u00eenceputul pandemiei. \r\n\u00a0 \r\nDar dac\u0103 sum\u0103m opiniile personalit\u0103\u021bilor de \u0219tiin\u021b\u0103 cu renume, la nivel mondial, atunci determinarea anticorpilor ar trebui considerat\u0103 util\u0103 \u0219i promi\u021b\u0103toare. \r\n\u00a0 \r\n<a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/A\/anticorpi-coronavirus-sars-cov-2-igm-3796\">Anticorpii\u00a0clasei M<\/strong><\/span><\/a>\r\n<ul>\r\n\t<li>Se mai numesc de faz\u0103 acut\u0103, care pot fi detectati deja la c\u00e2teva zile de la debutul simptomelor. Detectarea lor aleatorie (chiar \u0219i \u00een absen\u021ba simptomelor) indic\u0103 multiplicarea activ\u0103 (replicarea) virusului la momentul dat (chiar dac\u0103 rezultatele analizei PCR sunt negative). Dup\u0103 aproximativ 2 s\u0103pt\u0103m\u00e2ni, IgM dispar din fluxul sanguin.<\/li>\r\n<\/ul>\r\n\u00a0 \r\n<a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/A\/anticorpi-sars-cov-2-igg-3797\">\u00a0Anticorpii clasei G<\/strong>\u00a0<\/span><\/a>\r\n\r\n<ul>\r\n\t<li>Anume ace\u0219ti anticorpi sunt ast\u0103zi \u00een centrul aten\u021biei, nu doar a comunit\u0103\u021bii \u0219tiin\u021bifice mondiale, ci \u0219i a multor oameni, din cauza c\u0103 pe presupusele lor propriet\u0103\u021bi protectoare se pun mari speran\u021be. IgG apare \u00een s\u00e2nge la aproximativ 2 s\u0103pt\u0103m\u00e2ni de la primele simptome, iar detectarea lor (cu sau f\u0103r\u0103 IgM) indic\u0103 faptul c\u0103 a avut loc contactul cu virusul. Durata circula\u021biei IgG \u00een s\u00e2nge nu este cunoscut\u0103 ast\u0103zi din motive obiective.<\/li>\r\n\t<li>Prin defini\u021bie, IgG-urile trebuie s\u0103 ofere imunitate sau protec\u021bie la contactul repetat cu SARS-CoV-2. Adic\u0103, teoretic, persoanele cu IgG sunt imune, ceea ce \u00eenseamn\u0103 c\u0103 se pot \u00eentoarce la o \u201cvia\u021b\u0103 normal\u0103\u201d \u0219i la munc\u0103. \u00cens\u0103, \u00een ce m\u0103sur\u0103 \u0219i pentru c\u00e2t timp ace\u0219ti anticorpi protejeaz\u0103 \u00eentr-adev\u0103r o persoan\u0103, va ar\u0103ta doar timpul \u0219i cercet\u0103rile \u0219tiin\u021bifice suplimentare.<\/li>\r\n<\/ul>\r\n\u00a0 \r\nDificult\u0103\u021bi \u00een alegere<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Av\u00e2nd \u00een vedere cererea uria\u0219\u0103 de teste pentru determinarea anticorpilor, cel pu\u021bin 300 de produc\u0103tori din lume sunt implica\u021bi \u00een produc\u021bia test-sistemelor (reagen\u021bi), \u00een regim accelerat.<\/li>\r\n\t<li>Se ofer\u0103 diferite op\u021biuni: teste rapide bazate pe tehnologia imunocromatografic\u0103 (IC), ale c\u0103ror rezultate pot fi ob\u021binute \u00een decurs de 10-15 minute \u0219i teste bazate pe tehnologia imunoenzimatic\u0103 (ELISA), ale c\u0103ror rezultate pot fi ob\u021binute \u00een 1 sau mai multe zile. Metoda ELISA are mai multe avantaje fa\u021b\u0103 de metoda IC.<\/li>\r\n\t<li>Sistemele de testare propuse difer\u0103 foarte mult \u00een func\u021bie de caracteristicile diagnostice \u0219i nu doar: spectrul anticorpilor detecta\u021bi (M, A, G), sensibilitatea \u0219i specificitatea, corelarea cu rezultatele PCR (indicator nou), baza de dovezi (num\u0103rul de pacien\u021bi examina\u021bi utiliz\u00e2nd aceste sisteme de testare), statut de reglementare (CE, FDA, IVD, RUO), pre\u021b.<\/li>\r\n\t<li>Dar, potrivit oamenilor de \u0219tiin\u021b\u0103 cu renume, doar c\u00e2\u021biva produc\u0103tori au reu\u0219it s\u0103 creeze produse cu adev\u0103rat de \u00eenalt\u0103 calitate, care s\u0103 corespund\u0103 realit\u0103\u021bilor actuale.<\/li>\r\n<\/ul>\r\n\u00a0 \r\nCum au ales la ALFA diagnostica<\/strong><\/span> \r\n \r\nAnaliz\u00eend majoritatea ofertelor, ALFA diagnostica a ales mai mul\u021bi produc\u0103tori de test-sisteme din Germania \u0219i Spania. De ce? \r\n\u00a0\r\n<ul>\r\n\t<li>\u00cen primul r\u00e2nd<\/strong>, test-sistemele selectate sunt permise (validate) pentru utilizare clinic\u0103, adic\u0103 pentru examinarea pacien\u021bilor (certificat IVD), precum \u0219i, sunt aproba\u021bi pentru utilizare \u00een \u021b\u0103rile UE (certificat CE).<\/li>\r\n\t<li>\u00cen al doilea r\u00e2nd<\/strong>, precizia \u00eenalt\u0103 a sistemelor de testare a fost confirmat\u0103 de c\u0103tre produc\u0103tor prin studiile efectuate pe grupuri mari de pacien\u021bi cu COVID-19, \u0219i \u00een mod special, a fost dovedit\u0103 o corela\u021bie excelent\u0103 cu rezultatele PCR (detectarea direct\u0103 a virusului \u00een frotiurile nasofaringiene).<\/li>\r\n\t<li>\u00cen al treilea r\u00e2nd<\/strong>, test-sistemele demonstreaz\u0103 caracteristici diagnostice excelente:<\/li>\r\n<\/ul>\r\nSensibilitatea clinic\u0103 este > 98% - procentul de pacien\u021bi cu COVID-19 la care sistemul de testare detecteaz\u0103 anticorpi. Specificitatea clinic\u0103 este> 98% - procentul de persoane f\u0103r\u0103 COVID-19 pentru care sistemul de testare nu detecteaz\u0103 anticorpi. \r\n\u00a0 \r\nAstfel de caracteristici au fost ob\u021binute datorit\u0103 utilizarii de antigeni recombina\u021bi \u00eenalt specifici, care permit ob\u021binerea unei sensibilit\u0103\u021bi ridicate, evit\u00e2nd reac\u021biile \u00eencruci\u0219ate cu alte tulpini de coronavirus precum \u0219i cu al\u021bi agen\u021bi patogeni respiratori comuni.\u00a0 \u00a0\u00a0 \r\n\u00a0 \r\nAstfel, cercetarea anticorpilor \u00eembun\u0103t\u0103\u021be\u0219te calitatea diagnosticului de COVID-19, \u00een special la pacien\u021bii cu PCR-negativ, identific\u0103 persoanele cu imunitate, ajut\u0103 la analiza situa\u021biei epidemiologice, accelereaz\u0103 procesul de creare a unui vaccin eficient \u0219i serve\u0219te ca baz\u0103 pentru crearea unui \u201epa\u0219aport imunologic de s\u0103n\u0103tate\u201d.<\/em><\/strong> \r\n\u00a0","description_clear":"De la\u00a04 mai ALFA diagnostica anun\u021b\u0103 \u00eenceperea test\u0103rii pacien\u021bilor pentru prezen\u021ba anticorpilor la SARS-CoV-2 (COVID-19) prin metoda imunologic\u0103. Va fi apreciat\u0103 prezen\u021ba a dou\u0103 clase principale de anticorpii - IgM \u0219i IgG.\r\n\u00a0\r\nSubiectul anticorpilor SARS-CoV-2 este extrem de discutat \u0219i actual. Sunt multe \u00eentreb\u0103ri, la o bun\u0103 parte din care, este dificil sau chiar imposibil de r\u0103spuns, datorit\u0103 perioadei de timp destul de scurte care a trecut de la \u00eenceputul pandemiei.\r\n\u00a0\r\nDar dac\u0103 sum\u0103m opiniile personalit\u0103\u021bilor de \u0219tiin\u021b\u0103 cu renume, la nivel mondial, atunci determinarea anticorpilor ar trebui considerat\u0103 util\u0103 \u0219i promi\u021b\u0103toare.\r\n\u00a0\r\nAnticorpii\u00a0clasei M\r\n\r\n\tSe mai numesc de faz\u0103 acut\u0103, care pot fi detectati deja la c\u00e2teva zile de la debutul simptomelor. Detectarea lor aleatorie (chiar \u0219i \u00een absen\u021ba simptomelor) indic\u0103 multiplicarea activ\u0103 (replicarea) virusului la momentul dat (chiar dac\u0103 rezultatele analizei PCR sunt negative). Dup\u0103 aproximativ 2 s\u0103pt\u0103m\u00e2ni, IgM dispar din fluxul sanguin.\r\n\r\n\u00a0\r\n\u00a0Anticorpii clasei G\u00a0\r\n\r\n\r\n\tAnume ace\u0219ti anticorpi sunt ast\u0103zi \u00een centrul aten\u021biei, nu doar a comunit\u0103\u021bii \u0219tiin\u021bifice mondiale, ci \u0219i a multor oameni, din cauza c\u0103 pe presupusele lor propriet\u0103\u021bi protectoare se pun mari speran\u021be. IgG apare \u00een s\u00e2nge la aproximativ 2 s\u0103pt\u0103m\u00e2ni de la primele simptome, iar detectarea lor (cu sau f\u0103r\u0103 IgM) indic\u0103 faptul c\u0103 a avut loc contactul cu virusul. Durata circula\u021biei IgG \u00een s\u00e2nge nu este cunoscut\u0103 ast\u0103zi din motive obiective.\r\n\tPrin defini\u021bie, IgG-urile trebuie s\u0103 ofere imunitate sau protec\u021bie la contactul repetat cu SARS-CoV-2. Adic\u0103, teoretic, persoanele cu IgG sunt imune, ceea ce \u00eenseamn\u0103 c\u0103 se pot \u00eentoarce la o \u201cvia\u021b\u0103 normal\u0103\u201d \u0219i la munc\u0103. \u00cens\u0103, \u00een ce m\u0103sur\u0103 \u0219i pentru c\u00e2t timp ace\u0219ti anticorpi protejeaz\u0103 \u00eentr-adev\u0103r o persoan\u0103, va ar\u0103ta doar timpul \u0219i cercet\u0103rile \u0219tiin\u021bifice suplimentare.\r\n\r\n\u00a0\r\nDificult\u0103\u021bi \u00een alegere\r\n\r\n\r\n\tAv\u00e2nd \u00een vedere cererea uria\u0219\u0103 de teste pentru determinarea anticorpilor, cel pu\u021bin 300 de produc\u0103tori din lume sunt implica\u021bi \u00een produc\u021bia test-sistemelor (reagen\u021bi), \u00een regim accelerat.\r\n\tSe ofer\u0103 diferite op\u021biuni: teste rapide bazate pe tehnologia imunocromatografic\u0103 (IC), ale c\u0103ror rezultate pot fi ob\u021binute \u00een decurs de 10-15 minute \u0219i teste bazate pe tehnologia imunoenzimatic\u0103 (ELISA), ale c\u0103ror rezultate pot fi ob\u021binute \u00een 1 sau mai multe zile. Metoda ELISA are mai multe avantaje fa\u021b\u0103 de metoda IC.\r\n\tSistemele de testare propuse difer\u0103 foarte mult \u00een func\u021bie de caracteristicile diagnostice \u0219i nu doar: spectrul anticorpilor detecta\u021bi (M, A, G), sensibilitatea \u0219i specificitatea, corelarea cu rezultatele PCR (indicator nou), baza de dovezi (num\u0103rul de pacien\u021bi examina\u021bi utiliz\u00e2nd aceste sisteme de testare), statut de reglementare (CE, FDA, IVD, RUO), pre\u021b.\r\n\tDar, potrivit oamenilor de \u0219tiin\u021b\u0103 cu renume, doar c\u00e2\u021biva produc\u0103tori au reu\u0219it s\u0103 creeze produse cu adev\u0103rat de \u00eenalt\u0103 calitate, care s\u0103 corespund\u0103 realit\u0103\u021bilor actuale.\r\n\r\n\u00a0\r\nCum au ales la ALFA diagnostica\r\n\r\nAnaliz\u00eend majoritatea ofertelor, ALFA diagnostica a ales mai mul\u021bi produc\u0103tori de test-sisteme din Germania \u0219i Spania. De ce?\r\n\u00a0\r\n\r\n\t\u00cen primul r\u00e2nd, test-sistemele selectate sunt permise (validate) pentru utilizare clinic\u0103, adic\u0103 pentru examinarea pacien\u021bilor (certificat IVD), precum \u0219i, sunt aproba\u021bi pentru utilizare \u00een \u021b\u0103rile UE (certificat CE).\r\n\t\u00cen al doilea r\u00e2nd, precizia \u00eenalt\u0103 a sistemelor de testare a fost confirmat\u0103 de c\u0103tre produc\u0103tor prin studiile efectuate pe grupuri mari de pacien\u021bi cu COVID-19, \u0219i \u00een mod special, a fost dovedit\u0103 o corela\u021bie excelent\u0103 cu rezultatele PCR (detectarea direct\u0103 a virusului \u00een frotiurile nasofaringiene).\r\n\t\u00cen al treilea r\u00e2nd, test-sistemele demonstreaz\u0103 caracteristici diagnostice excelente:\r\n\r\nSensibilitatea clinic\u0103 este > 98% - procentul de pacien\u021bi cu COVID-19 la care sistemul de testare detecteaz\u0103 anticorpi. Specificitatea clinic\u0103 este> 98% - procentul de persoane f\u0103r\u0103 COVID-19 pentru care sistemul de testare nu detecteaz\u0103 anticorpi.\r\n\u00a0\r\nAstfel de caracteristici au fost ob\u021binute datorit\u0103 utilizarii de antigeni recombina\u021bi \u00eenalt specifici, care permit ob\u021binerea unei sensibilit\u0103\u021bi ridicate, evit\u00e2nd reac\u021biile \u00eencruci\u0219ate cu alte tulpini de coronavirus precum \u0219i cu al\u021bi agen\u021bi patogeni respiratori comuni.\u00a0 \u00a0\u00a0\r\n\u00a0\r\nAstfel, cercetarea anticorpilor \u00eembun\u0103t\u0103\u021be\u0219te calitatea diagnosticului de COVID-19, \u00een special la pacien\u021bii cu PCR-negativ, identific\u0103 persoanele cu imunitate, ajut\u0103 la analiza situa\u021biei epidemiologice, accelereaz\u0103 procesul de creare a unui vaccin eficient \u0219i serve\u0219te ca baz\u0103 pentru crearea unui \u201epa\u0219aport imunologic de s\u0103n\u0103tate\u201d.\r\n\u00a0","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/455\/1","url":"\/ro\/magazine\/anticorpi-catre-covid-19-455","url_full":"https:\/\/alfalab.md\/ro\/magazine\/anticorpi-catre-covid-19-455","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/anticorpi-catre-covid-19-455","show_startdate_d":"","show_enddate_d":"","date_d":"2020-04-30","show_startdate_text":"","show_enddate_text":"","date_text":"2020-04-30","date_day":"30","date_month":"Aprilie","date_published":"2021-11-18","date_modify":"2021-11-18","image_id":"196","image_ids":["196"],"image_url":"\/files\/getfile\/196\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/196\/","activegallery":[{"id":"247","parentclass":"magazine","idparentclass":"455","order":"1","idfile":"196","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/196\/","name":"57.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"454","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1587978000","views":null,"showonhome":"1","magazinetype":"2","name":"Alergie, grip\u0103 \u0219i COVID-19!","author":"author blog meta","info":null,"title":"Allergie, grip\u0103 \u0219i COVID-19!","urlsuffix":null,"description":"Nas \u00eenfundat, rinoree, febra \u2013 s\u0103 fie oare COVID-19? Doar simptome similare se reg\u0103sesc \u0219i \u00een alergii, \u0219i \u00een grip\u0103, precum \u0219i \u00een diferite infec\u021bii respiratorii. Cum s\u0103 \u00een\u021belegem \u0219i ce este de f\u0103cut? Speciali\u0219tii ALFA diagnostica au analizat literatura \u0219tiin\u021bific\u0103 \u0219i au prezentat rezultatele analizei lor \u00eentr-o form\u0103 accesibil\u0103. \r\n \r\n\u00a0\r\n<table border=\"0\" cellpadding=\"5\" cellspacing=\"0\" style=\"line-height:1;width:100%; font-size:12px\">\r\n\t<tbody>\r\n\t\t<tr>\r\n\t\t\t<td>\u00a0<\/td>\r\n\t\t\t<td style=\"width: 20%;\">COVID-19<\/strong><\/span><\/td>\r\n\t\t\t<td style=\"width: 20%;\">Infec\u021bii \r\n\t\t\trespiratorii<\/strong><\/span><\/td>\r\n\t\t\t<td style=\"width: 20%;\">Grip\u0103<\/strong><\/span><\/td>\r\n\t\t\t<td>Alergie \r\n\t\t\tsezonier\u0103<\/strong><\/span><\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"width: 20%;\">Simptome<\/strong><\/td>\r\n\t\t\t<td>De la u\u0219oare la severe<\/td>\r\n\t\t\t<td>Treptat<\/td>\r\n\t\t\t<td>Brusc<\/td>\r\n\t\t\t<td>Brusc<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Durata<\/strong><\/td>\r\n\t\t\t<td>7-25 zile<\/td>\r\n\t\t\t<td>< 14 zile<\/td>\r\n\t\t\t<td>7-14 zile<\/td>\r\n\t\t\t<td>C\u00e2teva s\u0103pt\u0103m\u00e2ini<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Tuse<\/strong><\/td>\r\n\t\t\t<td>Caracteristic \r\n\t\t\t(deobicei uscat\u0103)<\/td>\r\n\t\t\t<td>Caracteristic \r\n\t\t\t(u\u0219oar\u0103)<\/td>\r\n\t\t\t<td>Caracteristic \r\n\t\t\t(deobicei uscat\u0103)<\/td>\r\n\t\t\t<td>Mai rar \r\n\t\t\t(uscat\u0103, \u00een astm bron\u0219ic)<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Dispnee<\/strong><\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t\t<td>Nu<\/td>\r\n\t\t\t<td>Nu<\/td>\r\n\t\t\t<td>Nu (da, \u00een acutizarea astmului brion\u0219ic)<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Str\u0103nut<\/strong><\/td>\r\n\t\t\t<td>Nu<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t\t<td>Nu<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Rinoree<\/strong><\/td>\r\n\t\t\t<td>Rar<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Dureri \u00een g\u00eet<\/strong><\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t\t<td>C\u00eete odat\u0103 (nu este pronun\u021bat)<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Febr\u0103<\/strong><\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t\t<td>Perioad\u0103 scurt\u0103<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t\t<td>Nu<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Sl\u0103biciuni, oboseal\u0103<\/strong><\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Dureri de cap (cefalee)<\/strong><\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t\t<td>\u0420\u0435\u0434\u043a\u043e<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Dureri \u00een tot corpul<\/strong><\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t\t<td>Caracteristic<\/td>\r\n\t\t\t<td>Nu<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Diaree<\/strong><\/td>\r\n\t\t\t<td>Uneori<\/td>\r\n\t\t\t<td>Nu<\/td>\r\n\t\t\t<td>Uneori, la copii<\/td>\r\n\t\t\t<td>Nu<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Test de laborator<\/strong><\/td>\r\n\t\t\t<td>ARN SARS-CoV-2 \r\n\t\t\tCOVID-19<\/td>\r\n\t\t\t<td>Anticorpii agen\u021bilor \r\n\t\t\tpatogeni<\/td>\r\n\t\t\t<td>ARN Influenza virus \r\n\t\t\t\u0410 \/ \u0412 \/ RSV<\/td>\r\n\t\t\t<td>Testul alergologic \r\n\t\t\tALEX<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Material biologic<\/strong><\/td>\r\n\t\t\t<td>Frotiu din nazofaringe<\/td>\r\n\t\t\t<td>S\u00e2nge venos<\/td>\r\n\t\t\t<td>Frotiu din nazofaringe<\/td>\r\n\t\t\t<td>S\u00e2nge venos<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Codul testului<\/strong><\/td>\r\n\t\t\t<td>BML66<\/td>\r\n\t\t\t<td>MBI51<\/td>\r\n\t\t\t<td>BML63<\/td>\r\n\t\t\t<td>ALG23<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Timp de efectuare<\/strong><\/td>\r\n\t\t\t<td>1<\/td>\r\n\t\t\t<td>1<\/td>\r\n\t\t\t<td>1<\/td>\r\n\t\t\t<td>3<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td>Pre\u021b<\/strong><\/td>\r\n\t\t\t<td>600<\/td>\r\n\t\t\t<td>750<\/td>\r\n\t\t\t<td>2000<\/td>\r\n\t\t\t<td>2000<\/td>\r\n\t\t<\/tr>\r\n\t<\/tbody>\r\n<\/table>\r\n \r\n \r\nLa prezen\u021ba simptomelor (\u00een special febr\u0103 \u0219i tuse), apela\u021bi dup\u0103 ajutor medical.\u00a0<\/em><\/strong>","description_clear":"Nas \u00eenfundat, rinoree, febra \u2013 s\u0103 fie oare COVID-19? Doar simptome similare se reg\u0103sesc \u0219i \u00een alergii, \u0219i \u00een grip\u0103, precum \u0219i \u00een diferite infec\u021bii respiratorii. Cum s\u0103 \u00een\u021belegem \u0219i ce este de f\u0103cut? Speciali\u0219tii ALFA diagnostica au analizat literatura \u0219tiin\u021bific\u0103 \u0219i au prezentat rezultatele analizei lor \u00eentr-o form\u0103 accesibil\u0103.\r\n\r\n\u00a0\r\n\r\n\t\r\n\t\t\r\n\t\t\t\u00a0\r\n\t\t\tCOVID-19\r\n\t\t\tInfec\u021bii\r\n\t\t\trespiratorii\r\n\t\t\tGrip\u0103\r\n\t\t\tAlergie\r\n\t\t\tsezonier\u0103\r\n\t\t\r\n\t\t\r\n\t\t\tSimptome\r\n\t\t\tDe la u\u0219oare la severe\r\n\t\t\tTreptat\r\n\t\t\tBrusc\r\n\t\t\tBrusc\r\n\t\t\r\n\t\t\r\n\t\t\tDurata\r\n\t\t\t7-25 zile\r\n\t\t\t< 14 zile\r\n\t\t\t7-14 zile\r\n\t\t\tC\u00e2teva s\u0103pt\u0103m\u00e2ini\r\n\t\t\r\n\t\t\r\n\t\t\tTuse\r\n\t\t\tCaracteristic\r\n\t\t\t(deobicei uscat\u0103)\r\n\t\t\tCaracteristic\r\n\t\t\t(u\u0219oar\u0103)\r\n\t\t\tCaracteristic\r\n\t\t\t(deobicei uscat\u0103)\r\n\t\t\tMai rar\r\n\t\t\t(uscat\u0103, \u00een astm bron\u0219ic)\r\n\t\t\r\n\t\t\r\n\t\t\tDispnee\r\n\t\t\tUneori\r\n\t\t\tNu\r\n\t\t\tNu\r\n\t\t\tNu (da, \u00een acutizarea astmului brion\u0219ic)\r\n\t\t\r\n\t\t\r\n\t\t\tStr\u0103nut\r\n\t\t\tNu\r\n\t\t\tCaracteristic\r\n\t\t\tNu\r\n\t\t\tCaracteristic\r\n\t\t\r\n\t\t\r\n\t\t\tRinoree\r\n\t\t\tRar\r\n\t\t\tCaracteristic\r\n\t\t\tUneori\r\n\t\t\tCaracteristic\r\n\t\t\r\n\t\t\r\n\t\t\tDureri \u00een g\u00eet\r\n\t\t\tUneori\r\n\t\t\tCaracteristic\r\n\t\t\tUneori\r\n\t\t\tC\u00eete odat\u0103 (nu este pronun\u021bat)\r\n\t\t\r\n\t\t\r\n\t\t\tFebr\u0103\r\n\t\t\tCaracteristic\r\n\t\t\tPerioad\u0103 scurt\u0103\r\n\t\t\tCaracteristic\r\n\t\t\tNu\r\n\t\t\r\n\t\t\r\n\t\t\tSl\u0103biciuni, oboseal\u0103\r\n\t\t\tUneori\r\n\t\t\tUneori\r\n\t\t\tCaracteristic\r\n\t\t\tUneori\r\n\t\t\r\n\t\t\r\n\t\t\tDureri de cap (cefalee)\r\n\t\t\tUneori\r\n\t\t\t\u0420\u0435\u0434\u043a\u043e\r\n\t\t\tCaracteristic\r\n\t\t\tUneori\r\n\t\t\r\n\t\t\r\n\t\t\tDureri \u00een tot corpul\r\n\t\t\tUneori\r\n\t\t\tCaracteristic\r\n\t\t\tCaracteristic\r\n\t\t\tNu\r\n\t\t\r\n\t\t\r\n\t\t\tDiaree\r\n\t\t\tUneori\r\n\t\t\tNu\r\n\t\t\tUneori, la copii\r\n\t\t\tNu\r\n\t\t\r\n\t\t\r\n\t\t\tTest de laborator\r\n\t\t\tARN SARS-CoV-2\r\n\t\t\tCOVID-19\r\n\t\t\tAnticorpii agen\u021bilor\r\n\t\t\tpatogeni\r\n\t\t\tARN Influenza virus\r\n\t\t\t\u0410 \/ \u0412 \/ RSV\r\n\t\t\tTestul alergologic\r\n\t\t\tALEX\r\n\t\t\r\n\t\t\r\n\t\t\tMaterial biologic\r\n\t\t\tFrotiu din nazofaringe\r\n\t\t\tS\u00e2nge venos\r\n\t\t\tFrotiu din nazofaringe\r\n\t\t\tS\u00e2nge venos\r\n\t\t\r\n\t\t\r\n\t\t\tCodul testului\r\n\t\t\tBML66\r\n\t\t\tMBI51\r\n\t\t\tBML63\r\n\t\t\tALG23\r\n\t\t\r\n\t\t\r\n\t\t\tTimp de efectuare\r\n\t\t\t1\r\n\t\t\t1\r\n\t\t\t1\r\n\t\t\t3\r\n\t\t\r\n\t\t\r\n\t\t\tPre\u021b\r\n\t\t\t600\r\n\t\t\t750\r\n\t\t\t2000\r\n\t\t\t2000\r\n\t\t\r\n\t\r\n\r\n\r\n\r\nLa prezen\u021ba simptomelor (\u00een special febr\u0103 \u0219i tuse), apela\u021bi dup\u0103 ajutor medical.\u00a0","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/454\/1","url":"\/ro\/magazine\/alergie-gripa-si-covid-19-454","url_full":"https:\/\/alfalab.md\/ro\/magazine\/alergie-gripa-si-covid-19-454","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/alergie-gripa-si-covid-19-454","show_startdate_d":"","show_enddate_d":"","date_d":"2020-04-27","show_startdate_text":"","show_enddate_text":"","date_text":"2020-04-27","date_day":"27","date_month":"Aprilie","date_published":"2021-11-18","date_modify":"2021-11-18","image_id":"195","image_ids":["195"],"image_url":"\/files\/getfile\/195\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/195\/","activegallery":[{"id":"246","parentclass":"magazine","idparentclass":"454","order":"1","idfile":"195","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/195\/","name":"56.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"453","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1587373200","views":null,"showonhome":"1","magazinetype":"2","name":"Testare molecular\u0103 COVID-19","author":"author blog meta","info":null,"title":"Testare molecular\u0103 COVID-19","urlsuffix":null,"description":"Laboratorul medical ALFA diagnostica anun\u021b\u0103 \u00eenceperea test\u0103rii pentru <a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/A\/arn-sars-cov-2-tampon-nazofaringian-3788\">SARS-CoV-2 <\/span><\/a>(COVID-19) prin metoda reac\u021biei de polimerizare \u00een lan\u021b \u00een timp real, care permite determinarea ARN-ului patogen din frotiul mucoasei nazale \u0219i a nazofaringelui. \r\n\u00a0 \r\nCare sunt caracteristicile reagen\u021bilor\/test-sisteme pentru SARS-CoV-2 (COVID-19) la ALFA diagnostica \u0219i care este diferen\u021ba fa\u021b\u0103 de testele similare ale altor laboratoare comerciale?<\/em><\/span> \r\n\u00a0 \r\n\u00cen primul r\u00e2nd<\/strong>, reagen\u021bii folosi\u021bi de ALFA diagnostica sunt omologa\u021bi pentru utilizare clinic\u0103, adic\u0103 sunt valida\u021bi de c\u0103tre produc\u0103tor pentru efectuarea examin\u0103rii anume asupra pacien\u021bilor - pentru care produc\u0103torul poart\u0103 responsabilitate. Astfel de reagen\u021bi sunt marca\u021bi - IVD.\r\n<ul>\r\n\t<li>Acest aspect este extrem de important deoarece p\u00e2n\u0103 \u00een prezent, un num\u0103r semnificativ de persoane au fost deja testate folosind reagen\u021bi care nu sunt destina\u021bi utiliz\u0103rii diagnostice, dar sunt destina\u021bi doar utiliz\u0103rii \u00een scop\u00a0 \u0219tiin\u021bific, de cercetare sau experimentale (acestea din urm\u0103 sunt marcate RUO - Research Use Only) \u0219i, de regul\u0103, nu au date referitor la sensibilitate, specificitate, praguri de determinare \u0219i alte informa\u021bii relevante.<\/li>\r\n<\/ul>\r\n\u00a0 \r\n\u00cen al doilea r\u00e2nd<\/strong>, reagen\u021bii folosi\u021bi de ALFA diagnostica detecteaz\u0103 cel pu\u021bin 2 \u021binte moleculare \u00een ARN-ul viral, ceea ce corespunde, pe deplin, recomand\u0103rilor OMS.\r\n\r\n<ul>\r\n\t<li>S-a stabilit c\u0103 o singur\u0103 \u021bint\u0103 molecular\u0103 nu poate genera (garanta) un rezultat fiabil! Viru\u0219ii care con\u021bin ARN pot muta, ceea ce \u00eenseamn\u0103 c\u0103 o muta\u021bie \u00eentr-o singur\u0103 \u021bint\u0103 poate \u201estopa\u201d capacitatea test-sistemului de a detecta SARS-CoV-2 (COVID-19) sau poate duce spre exemplu, la detectarea unui alt virus asem\u0103n\u0103tor cu SARS,\u00a0 \u00een mod special SARS-CoV sau MERS-CoV.<\/li>\r\n<\/ul>\r\n\u00a0 \r\n\u00cen al treilea r\u00e2nd<\/strong>, reagen\u021bii folosi\u021bi de ALFA diagnostica au caracteristici excelente: sensibilitate - 100% (testul este pozitiv la 100% dintre pacien\u021bii cu COVID-19), specificitate - 100% (testul este negativ la 100% dintre persoanele f\u0103r\u0103 COVID-19), sensibilitatea analitic\u0103 < 10 copii de ARN \u00een prob\u0103!\r\n\r\n<ul>\r\n\t<li>Astfel de caracteristici sunt printre cele mai bune de pe pia\u021b\u0103. Prin urmare, pacien\u021bii trebuie s\u0103 se intereseze \u0219i s\u0103 cunoasc\u0103 caracteristicile diagnostice ale test-sistemelor folosite.<\/li>\r\n<\/ul>\r\n\u00a0 \r\n\u00cen al patrulea r\u00e2nd<\/strong>, prelevarea biomaterialul este efectuat\u0103 de c\u0103tre angaja\u021bii califica\u021bi ALFA diagnostica, \u00een conformitate cu cerin\u021bele etapei preanalitice, fapt care influen\u021beaz\u0103 direct fiabilitatea rezultatului test\u0103rii.\r\n\r\n<ul>\r\n\t<li>Studiile \u0219tiin\u021bifice arat\u0103 \u00een mod conving\u0103tor c\u0103, prelevarea desinestat\u0103toare a unui frotiu din mucoas\u0103 este cauza cea mai frecvent\u0103 a rezultatelor fals-negative (rezultat negativ cu toate c\u0103 este prezent virusul \u00een organism).<\/li>\r\n<\/ul>\r\n\r\n<div style=\"clear:both;\">\u00a0<\/div>","description_clear":"Laboratorul medical ALFA diagnostica anun\u021b\u0103 \u00eenceperea test\u0103rii pentru SARS-CoV-2 (COVID-19) prin metoda reac\u021biei de polimerizare \u00een lan\u021b \u00een timp real, care permite determinarea ARN-ului patogen din frotiul mucoasei nazale \u0219i a nazofaringelui.\r\n\u00a0\r\nCare sunt caracteristicile reagen\u021bilor\/test-sisteme pentru SARS-CoV-2 (COVID-19) la ALFA diagnostica \u0219i care este diferen\u021ba fa\u021b\u0103 de testele similare ale altor laboratoare comerciale?\r\n\u00a0\r\n\u00cen primul r\u00e2nd, reagen\u021bii folosi\u021bi de ALFA diagnostica sunt omologa\u021bi pentru utilizare clinic\u0103, adic\u0103 sunt valida\u021bi de c\u0103tre produc\u0103tor pentru efectuarea examin\u0103rii anume asupra pacien\u021bilor - pentru care produc\u0103torul poart\u0103 responsabilitate. Astfel de reagen\u021bi sunt marca\u021bi - IVD.\r\n\r\n\tAcest aspect este extrem de important deoarece p\u00e2n\u0103 \u00een prezent, un num\u0103r semnificativ de persoane au fost deja testate folosind reagen\u021bi care nu sunt destina\u021bi utiliz\u0103rii diagnostice, dar sunt destina\u021bi doar utiliz\u0103rii \u00een scop\u00a0 \u0219tiin\u021bific, de cercetare sau experimentale (acestea din urm\u0103 sunt marcate RUO - Research Use Only) \u0219i, de regul\u0103, nu au date referitor la sensibilitate, specificitate, praguri de determinare \u0219i alte informa\u021bii relevante.\r\n\r\n\u00a0\r\n\u00cen al doilea r\u00e2nd, reagen\u021bii folosi\u021bi de ALFA diagnostica detecteaz\u0103 cel pu\u021bin 2 \u021binte moleculare \u00een ARN-ul viral, ceea ce corespunde, pe deplin, recomand\u0103rilor OMS.\r\n\r\n\r\n\tS-a stabilit c\u0103 o singur\u0103 \u021bint\u0103 molecular\u0103 nu poate genera (garanta) un rezultat fiabil! Viru\u0219ii care con\u021bin ARN pot muta, ceea ce \u00eenseamn\u0103 c\u0103 o muta\u021bie \u00eentr-o singur\u0103 \u021bint\u0103 poate \u201estopa\u201d capacitatea test-sistemului de a detecta SARS-CoV-2 (COVID-19) sau poate duce spre exemplu, la detectarea unui alt virus asem\u0103n\u0103tor cu SARS,\u00a0 \u00een mod special SARS-CoV sau MERS-CoV.\r\n\r\n\u00a0\r\n\u00cen al treilea r\u00e2nd, reagen\u021bii folosi\u021bi de ALFA diagnostica au caracteristici excelente: sensibilitate - 100% (testul este pozitiv la 100% dintre pacien\u021bii cu COVID-19), specificitate - 100% (testul este negativ la 100% dintre persoanele f\u0103r\u0103 COVID-19), sensibilitatea analitic\u0103 < 10 copii de ARN \u00een prob\u0103!\r\n\r\n\r\n\tAstfel de caracteristici sunt printre cele mai bune de pe pia\u021b\u0103. Prin urmare, pacien\u021bii trebuie s\u0103 se intereseze \u0219i s\u0103 cunoasc\u0103 caracteristicile diagnostice ale test-sistemelor folosite.\r\n\r\n\u00a0\r\n\u00cen al patrulea r\u00e2nd, prelevarea biomaterialul este efectuat\u0103 de c\u0103tre angaja\u021bii califica\u021bi ALFA diagnostica, \u00een conformitate cu cerin\u021bele etapei preanalitice, fapt care influen\u021beaz\u0103 direct fiabilitatea rezultatului test\u0103rii.\r\n\r\n\r\n\tStudiile \u0219tiin\u021bifice arat\u0103 \u00een mod conving\u0103tor c\u0103, prelevarea desinestat\u0103toare a unui frotiu din mucoas\u0103 este cauza cea mai frecvent\u0103 a rezultatelor fals-negative (rezultat negativ cu toate c\u0103 este prezent virusul \u00een organism).\r\n\r\n\r\n\u00a0","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/453\/1","url":"\/ro\/magazine\/testare-moleculara-covid-19-453","url_full":"https:\/\/alfalab.md\/ro\/magazine\/testare-moleculara-covid-19-453","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/testare-moleculara-covid-19-453","show_startdate_d":"","show_enddate_d":"","date_d":"2020-04-20","show_startdate_text":"","show_enddate_text":"","date_text":"2020-04-20","date_day":"20","date_month":"Aprilie","date_published":"2021-11-18","date_modify":"2021-11-18","image_id":"194","image_ids":["194"],"image_url":"\/files\/getfile\/194\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/194\/","activegallery":[{"id":"245","parentclass":"magazine","idparentclass":"453","order":"1","idfile":"194","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/194\/","name":"55.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"452","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1583229600","views":null,"showonhome":"1","magazinetype":"2","name":"Organismul d-voastr\u0103 are suficien\u021bi antioxidan\u021bi?","author":"author blog meta","info":null,"title":"Organismul d-voastr\u0103 are suficien\u021bi antioxidan\u021bi?","urlsuffix":null,"description":"\u00cen acela\u0219i timp, \u00een organism apar miliarde de reac\u021bii biochimice care genereaz\u0103 formarea moleculelor extrem de reactive chimic \u2013 forme active de oxigen (ROS) \u0219i azot (RNS). \u00cen condi\u021bii normale, fiziologice, aceste molecule (numite oxidan\u021bi) nu au efecte d\u0103un\u0103toare asupra celulelor corpului, deoarece excesul lor este neutralizat de un sistem antioxidant complicat (SAO). Adic\u0103, \u00een mod normal, procesele oxidante \u0219i antioxidante sunt echilibrate. \r\n\u00a0 \r\nCu toate acestea, exist\u0103 circumstan\u021be \u00een care echilibrul dintre cele dou\u0103 sisteme este perturbat, iar apoi moleculele intens reactive, \"slab re\u021binute\" SAO, \u00eencep s\u0103 deterioreze membranele celulare, proteinele, lipidele, inclusiv informa\u021biile genetice ale ADN-ului. \r\n \r\nAstfel, echilibrul este perturbat sau datorit\u0103 cre\u0219terii form\u0103rii de oxidan\u021bi, sau datorit\u0103 sc\u0103derii concentra\u021biei de antioxidan\u021bi, sau datorit\u0103 ambelor. Acest dezachilibru se nume\u0219te stres oxidativ.<\/strong> \r\n \r\nLA CE DUCE STRESUL OXIDATIV?<\/strong><\/span> \r\n\u00a0 \r\nPe termen lung, procesele de \u00eemb\u0103tr\u00e2nire sunt accelerate \u0219i, de asemenea, cre\u0219te riscul de a dezvolta diferite boli: \r\n\u00a0 \r\nBoli cardiovasculare<\/strong>\r\n<ul>\r\n\t<li>Boal\u0103 cardiac\u0103 ischemic\u0103 \/ insuficien\u021b\u0103 cardiac\u0103<\/li>\r\n\t<li>Ateroscleroza<\/li>\r\n\t<li>Hipertensiune arterial\u0103<\/li>\r\n<\/ul>\r\nBoli neurodegenerative<\/strong>\r\n\r\n<ul>\r\n\t<li>Maladia Alzheimer, maladia Parkinson, scleroza lateral\u0103 amiotrofic\u0103 (SLA)<\/li>\r\n<\/ul>\r\nTulbur\u0103ri\u00a0 vizuale<\/strong>\r\n\r\n<ul>\r\n\t<li>Degenerescen\u021ba macular\u0103 legat\u0103 de v\u00e2rst\u0103 (DMLV), cataracta<\/li>\r\n<\/ul>\r\nBoli ale sistemului endocrin<\/strong>\r\n\r\n<ul>\r\n\t<li>Diabet\u00a0 zaharat<\/li>\r\n<\/ul>\r\nBoli ale tractului gastro-intestinal<\/strong>\r\n\r\n<ul>\r\n\t<li>Boli inflamatorii intestinale,<\/li>\r\n\t<li>Pancreatit\u0103,<\/li>\r\n\t<li>Hepatit\u0103, hepatoz\u0103<\/li>\r\n<\/ul>\r\nBoli ale pielii<\/strong>\r\n\r\n<ul>\r\n\t<li>Porfirie cutanat\u0103, leziuni UV ale pielii<\/li>\r\n<\/ul>\r\nBoli pulmonare<\/strong>\r\n\r\n<ul>\r\n\t<li>Emfizem pulmonar, astm<\/li>\r\n<\/ul>\r\nBoli ale s\u00e2ngelui \u0219i ale sistemului imunitar<\/strong>\r\n\r\n<ul>\r\n\t<li>Anemie, alergii, imunodeficien\u021be<\/li>\r\n<\/ul>\r\nBoli infec\u021bioase<\/strong>\r\n\r\n<ul>\r\n\t<li>Infec\u021bii recurente<\/li>\r\n<\/ul>\r\n\u00ceN CE SITUA\u021aII SE RECOMAND\u0102 EVALUAREA \"PERFORMAN\u021aEI\" PROTEC\u021aIEI ANTIOXIDANTE?<\/strong><\/span>\r\n\r\n<ul>\r\n\t<li>Fumatul<\/li>\r\n\t<li>Stresul fizic \u0219i \/ sau psihologic de lung\u0103 durat\u0103<\/li>\r\n\t<li>Impactul polu\u0103rii extreme a aerului, pesticidelor, medicamentelor, radia\u021biilor ionizante<\/li>\r\n\t<li>Sport intens<\/li>\r\n\t<li>Suspec\u021bie\u00a0 la\u00a0 imunodeficien\u021b\u0103<\/li>\r\n\t<li>Boli inflamatorii cronice<\/li>\r\n\t<li>Infec\u021bii recurente<\/li>\r\n\t<li>Boal\u0103 renal\u0103 cronic\u0103 \u0219i Dializ\u0103<\/li>\r\n\t<li>Boal\u0103 cardiac\u0103 ischemic\u0103 \/ insuficien\u021b\u0103 cardiac\u0103<\/li>\r\n\t<li>Hipertensiune arterial\u0103<\/li>\r\n\t<li>Hipercolesterolemie \/ ateroscleroz\u0103<\/li>\r\n\t<li>Diabet\u00a0 zaharat<\/li>\r\n\t<li>C\u0103derea p\u0103rului( alopecie)<\/li>\r\n\t<li>Oboseal\u0103 cronic\u0103<\/li>\r\n<\/ul>\r\nCE TEST\u0102M?<\/strong><\/span> \r\n \r\nPentru a identifica reducerea poten\u021bialului antioxidant general<\/strong>, se recomand\u0103 determinarea:\r\n\r\n<ol>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/A\/activitate-antioxidanta-serica-3165\">Activitate antioxidant\u0103 seric\u0103<\/span><\/a><\/li>\r\n<\/ol>\r\nAcesta \u2013 este un test de screening pentru evaluarea general\u0103 a poten\u021bialului SAO.<\/em> \r\n \r\nPentru a detecta reducerea componentelor individuale ale sistemului antioxidant<\/strong>, se recomand\u0103 determinarea:<\/span>\r\n\r\n<ol>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/S\/superoxiddismutaza-sod-3659\">Superoxiddismutaz\u0103, SOD<\/span><\/a><\/li>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/H\/hidroxipurina-in-urina-3387\">Glutationperoxidaz\u0103<\/span><\/a><\/li>\r\n<\/ol>\r\n <\/span>Ace\u0219tia \u2013 sunt antioxidan\u021bii prim<\/span>ari ai organismului \u0219i enzimele cheie ale protec\u021biei antioxidante.<\/em>\r\n\r\n<ol>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/V\/vitamina-e-tocoferol-3373\">Vitamina E, Tocoferol<\/span><\/a><\/li>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/V\/vitamina-c-acidul-ascorbic-3375\">Vitamina C, Acidul ascorbic<\/span><\/a><\/li>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/B\/beta-carotenul-3350\">Beta (\u03b2)-carotenul<\/span><\/a><\/li>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/C\/coenzima-q10-3490\">Coenzima Q10<\/span><\/a><\/li>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/S\/seleniul-in-ser-3644\">Seleniul \u00een ser<\/span><\/a><\/li>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/Z\/zinc-82\">Zinc<\/span><\/a><\/li>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/M\/magneziu-79\">Magneziu<\/span><\/a><\/li>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/C\/cupru-80\">Cupru<\/span><\/a><\/li>\r\n<\/ol>\r\nAce\u0219tia \u2013\u00a0 sunt antioxidan\u021bi secundari care intr\u0103 \u00een organism cu alimente.<\/em> \r\n \r\nPentru a detecta deteriorarea componentelor celulei<\/strong>, se recomand\u0103 determinarea:\r\n\r\n<ol>\r\n\t<li><a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/M\/malondialdehida-mda-3519\">Malondialdehida, MDA<\/span><\/a><\/li>\r\n<\/ol>\r\n\u00a0Acesta \u2013\u00a0 este un marker cheie al leziunii oxidative a lipidelor membranelor celulare.<\/em> \r\n \r\nSursa<\/strong> \r\nRecomand\u0103rile Institutului Robert Koch","description_clear":"\u00cen acela\u0219i timp, \u00een organism apar miliarde de reac\u021bii biochimice care genereaz\u0103 formarea moleculelor extrem de reactive chimic \u2013 forme active de oxigen (ROS) \u0219i azot (RNS). \u00cen condi\u021bii normale, fiziologice, aceste molecule (numite oxidan\u021bi) nu au efecte d\u0103un\u0103toare asupra celulelor corpului, deoarece excesul lor este neutralizat de un sistem antioxidant complicat (SAO). Adic\u0103, \u00een mod normal, procesele oxidante \u0219i antioxidante sunt echilibrate.\r\n\u00a0\r\nCu toate acestea, exist\u0103 circumstan\u021be \u00een care echilibrul dintre cele dou\u0103 sisteme este perturbat, iar apoi moleculele intens reactive, \"slab re\u021binute\" SAO, \u00eencep s\u0103 deterioreze membranele celulare, proteinele, lipidele, inclusiv informa\u021biile genetice ale ADN-ului.\r\n\r\nAstfel, echilibrul este perturbat sau datorit\u0103 cre\u0219terii form\u0103rii de oxidan\u021bi, sau datorit\u0103 sc\u0103derii concentra\u021biei de antioxidan\u021bi, sau datorit\u0103 ambelor. Acest dezachilibru se nume\u0219te stres oxidativ.\r\n\r\nLA CE DUCE STRESUL OXIDATIV?\r\n\u00a0\r\nPe termen lung, procesele de \u00eemb\u0103tr\u00e2nire sunt accelerate \u0219i, de asemenea, cre\u0219te riscul de a dezvolta diferite boli:\r\n\u00a0\r\nBoli cardiovasculare\r\n\r\n\tBoal\u0103 cardiac\u0103 ischemic\u0103 \/ insuficien\u021b\u0103 cardiac\u0103\r\n\tAteroscleroza\r\n\tHipertensiune arterial\u0103\r\n\r\nBoli neurodegenerative\r\n\r\n\r\n\tMaladia Alzheimer, maladia Parkinson, scleroza lateral\u0103 amiotrofic\u0103 (SLA)\r\n\r\nTulbur\u0103ri\u00a0 vizuale\r\n\r\n\r\n\tDegenerescen\u021ba macular\u0103 legat\u0103 de v\u00e2rst\u0103 (DMLV), cataracta\r\n\r\nBoli ale sistemului endocrin\r\n\r\n\r\n\tDiabet\u00a0 zaharat\r\n\r\nBoli ale tractului gastro-intestinal\r\n\r\n\r\n\tBoli inflamatorii intestinale,\r\n\tPancreatit\u0103,\r\n\tHepatit\u0103, hepatoz\u0103\r\n\r\nBoli ale pielii\r\n\r\n\r\n\tPorfirie cutanat\u0103, leziuni UV ale pielii\r\n\r\nBoli pulmonare\r\n\r\n\r\n\tEmfizem pulmonar, astm\r\n\r\nBoli ale s\u00e2ngelui \u0219i ale sistemului imunitar\r\n\r\n\r\n\tAnemie, alergii, imunodeficien\u021be\r\n\r\nBoli infec\u021bioase\r\n\r\n\r\n\tInfec\u021bii recurente\r\n\r\n\u00ceN CE SITUA\u021aII SE RECOMAND\u0102 EVALUAREA \"PERFORMAN\u021aEI\" PROTEC\u021aIEI ANTIOXIDANTE?\r\n\r\n\r\n\tFumatul\r\n\tStresul fizic \u0219i \/ sau psihologic de lung\u0103 durat\u0103\r\n\tImpactul polu\u0103rii extreme a aerului, pesticidelor, medicamentelor, radia\u021biilor ionizante\r\n\tSport intens\r\n\tSuspec\u021bie\u00a0 la\u00a0 imunodeficien\u021b\u0103\r\n\tBoli inflamatorii cronice\r\n\tInfec\u021bii recurente\r\n\tBoal\u0103 renal\u0103 cronic\u0103 \u0219i Dializ\u0103\r\n\tBoal\u0103 cardiac\u0103 ischemic\u0103 \/ insuficien\u021b\u0103 cardiac\u0103\r\n\tHipertensiune arterial\u0103\r\n\tHipercolesterolemie \/ ateroscleroz\u0103\r\n\tDiabet\u00a0 zaharat\r\n\tC\u0103derea p\u0103rului( alopecie)\r\n\tOboseal\u0103 cronic\u0103\r\n\r\nCE TEST\u0102M?\r\n\r\nPentru a identifica reducerea poten\u021bialului antioxidant general, se recomand\u0103 determinarea:\r\n\r\n\r\n\tActivitate antioxidant\u0103 seric\u0103\r\n\r\nAcesta \u2013 este un test de screening pentru evaluarea general\u0103 a poten\u021bialului SAO.\r\n\r\nPentru a detecta reducerea componentelor individuale ale sistemului antioxidant, se recomand\u0103 determinarea:\r\n\r\n\r\n\tSuperoxiddismutaz\u0103, SOD\r\n\tGlutationperoxidaz\u0103\r\n\r\n Ace\u0219tia \u2013 sunt antioxidan\u021bii primari ai organismului \u0219i enzimele cheie ale protec\u021biei antioxidante.\r\n\r\n\r\n\tVitamina E, Tocoferol\r\n\tVitamina C, Acidul ascorbic\r\n\tBeta (\u03b2)-carotenul\r\n\tCoenzima Q10\r\n\tSeleniul \u00een ser\r\n\tZinc\r\n\tMagneziu\r\n\tCupru\r\n\r\nAce\u0219tia \u2013\u00a0 sunt antioxidan\u021bi secundari care intr\u0103 \u00een organism cu alimente.\r\n\r\nPentru a detecta deteriorarea componentelor celulei, se recomand\u0103 determinarea:\r\n\r\n\r\n\tMalondialdehida, MDA\r\n\r\n\u00a0Acesta \u2013\u00a0 este un marker cheie al leziunii oxidative a lipidelor membranelor celulare.\r\n\r\nSursa\r\nRecomand\u0103rile Institutului Robert Koch","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/452\/1","url":"\/ro\/magazine\/organismul-d-voastra-are-suficienti-antioxidanti-452","url_full":"https:\/\/alfalab.md\/ro\/magazine\/organismul-d-voastra-are-suficienti-antioxidanti-452","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/organismul-d-voastra-are-suficienti-antioxidanti-452","show_startdate_d":"","show_enddate_d":"","date_d":"2020-03-03","show_startdate_text":"","show_enddate_text":"","date_text":"2020-03-03","date_day":"03","date_month":"Martie","date_published":"2021-11-18","date_modify":"2021-11-18","image_id":"193","image_ids":["193"],"image_url":"\/files\/getfile\/193\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/193\/","activegallery":[{"id":"244","parentclass":"magazine","idparentclass":"452","order":"1","idfile":"193","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/193\/","name":"54.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"450","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1576231200","views":null,"showonhome":"1","magazinetype":"2","name":"S\u00e2nge \u00een urin\u0103. Tumoare a vezicii urinare?","author":"author blog meta","info":null,"title":"S\u00e2nge \u00een urin\u0103. Tumoare a vezicii urinare?","urlsuffix":null,"description":"Anual \u00een Moldova, peste 300 de persoane se \u00eemboln\u0103vesc de cancer al vezicii urinare. Boala este de 3 ori mai frecvent\u0103 la b\u0103rba\u021bi dec\u00e2t la femei. Pentru Europa, aceste cifre sunt \u0219i mai triste \u2013 125 000 de oameni!<\/strong> \r\n\u00a0 \r\nUnul dintre principalii factori de risc se consider\u0103 fumatul! De asemenea, v\u00e2rsta \u0219i activitatea profesional\u0103 \u00een industria cauciucului, a vopselei \u0219i a lacurilor, a h\u00e2rtiei \u0219i a produselor chimice. \u00cen mod curios, debutul dezvolt\u0103rii bolii este par\u021bial determinat de momentul de contact \u00eentre cancerigenul excretat \u00een urin\u0103 \u0219i mucoasa vezicii urinare. Adic\u0103, cu c\u00e2t acest timp este mai scurt, cu at\u00e2t riscul este mai mic. Din acest motiv, golirea la timp a acestuia poate fi considerat\u0103 o m\u0103sur\u0103 standard de prevenire. \u00cen special pentru \u0219oferii de curs\u0103 lung\u0103, atunci c\u00e2nd apare dorin\u021ba de a urina, ace\u0219tia nu au posibilitatea de a goli vezica urinar\u0103.<\/em> \r\n \r\nPrimele suspiciuni<\/span>\r\n<ul>\r\n\t<li>Este dificil de suspectat tumoarea, deoarece orice tulburare urinar\u0103 poate ap\u0103rea \u0219i cu boli urologice benigne (prostatita, cistita, adenom, infec\u021bie sau urolitiaz\u0103).<\/li>\r\n<\/ul>\r\nSimptomele bolii<\/span>\r\n\r\n<ul>\r\n\t<li>Principalele semne, de\u0219i nu sunt obligatorii a cancerului vezicii urinare sunt: apari\u021bia s\u00e2ngelui \u00een urin\u0103 \u0219i urinare dureroas\u0103 frecvent\u0103.<\/li>\r\n<\/ul>\r\nConcentrare pe simptome?<\/span>\r\n\r\n<ul>\r\n\t<li>Nu! Cu siguran\u021b\u0103 \u201castfel de simptome nu se merit\u0103 de a\u0219teptat\u201d \u2013\u00a0 90% dintre persoanele care au ca simptom clinic prezen\u021ba s\u00e2ngelui \u00een urin\u0103, nu sunt bolnavi de cancer al vezicii urinare. \u00cens\u0103 ignorarea acestui fapt duce la anxietate \u0219i la stres sever fiec\u0103rei persoane.<\/li>\r\n<\/ul>\r\nExclude\u021bi suspiciunile<\/span>\r\n\r\n<ul>\r\n\t<li>Pentru prima dat\u0103 \u00een Moldova, \u00een centrul medical ALFA diagnostica a fost implementat cu succes testul - <a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/A\/analiza-expresiei-a-genelor-upk1b-igf2-crh-anxa10-abl1-detectarea-cancerului-vezicii-urinare-2173\">Xpert Bladder Cancer Detection<\/span><\/a><\/strong> pentru detectarea cancerului vezicii urinare. Tehnologia patentat\u0103\u00a0 se bazeaz\u0103 pe determinarea \u00een urin\u0103 a cinci markeri moleculari dovedi\u021bi ai cancerului cu un grad sc\u0103zut \u0219i \u00eenalt de agresivitate.<\/li>\r\n<\/ul>\r\nValoarea special\u0103 a testului este c\u0103 rezultatul s\u0103u negativ \r\nindic\u0103 absen\u021ba cancerului cu o probabilitate de 98%!<\/strong><\/span> \r\n\u00a0 \r\nDe asemenea, testul poate detecta recidive la pacien\u021bii care au avut deja cancer de vezic\u0103 urinar\u0103. Timpul s\u0103u de execu\u021bie este de doar 3 ore! Testul se efectueaz\u0103 din urin\u0103 \u0219i nu necesit\u0103 preg\u0103tire special\u0103. Pre\u021bul testului \u2013 4000 lei<\/strong>.\u00a0 \r\n\u00a0 \r\nIMPORTANT!<\/span>\r\n\r\n<ul>\r\n\t<li>Pacien\u021bilor, ce l-i sa prelevat urina pentru analiz\u0103 \u00een laboratorul central de pe strada N. Testemi\u021banu, 21, primesc rezultatul \u00een timp de 3 ore, \u00een filialele laboratorului din Chi\u0219in\u0103u \u2013 \u00een aceia\u0219i zi<\/strong>, filiala din B\u0103l\u021bi \u2013 a doua <\/strong>zi.<\/li>\r\n<\/ul>\r\n\r\n<div style=\"clear:both;\">\u00a0<\/div>","description_clear":"Anual \u00een Moldova, peste 300 de persoane se \u00eemboln\u0103vesc de cancer al vezicii urinare. Boala este de 3 ori mai frecvent\u0103 la b\u0103rba\u021bi dec\u00e2t la femei. Pentru Europa, aceste cifre sunt \u0219i mai triste \u2013 125 000 de oameni!\r\n\u00a0\r\nUnul dintre principalii factori de risc se consider\u0103 fumatul! De asemenea, v\u00e2rsta \u0219i activitatea profesional\u0103 \u00een industria cauciucului, a vopselei \u0219i a lacurilor, a h\u00e2rtiei \u0219i a produselor chimice. \u00cen mod curios, debutul dezvolt\u0103rii bolii este par\u021bial determinat de momentul de contact \u00eentre cancerigenul excretat \u00een urin\u0103 \u0219i mucoasa vezicii urinare. Adic\u0103, cu c\u00e2t acest timp este mai scurt, cu at\u00e2t riscul este mai mic. Din acest motiv, golirea la timp a acestuia poate fi considerat\u0103 o m\u0103sur\u0103 standard de prevenire. \u00cen special pentru \u0219oferii de curs\u0103 lung\u0103, atunci c\u00e2nd apare dorin\u021ba de a urina, ace\u0219tia nu au posibilitatea de a goli vezica urinar\u0103.\r\n\r\nPrimele suspiciuni\r\n\r\n\tEste dificil de suspectat tumoarea, deoarece orice tulburare urinar\u0103 poate ap\u0103rea \u0219i cu boli urologice benigne (prostatita, cistita, adenom, infec\u021bie sau urolitiaz\u0103).\r\n\r\nSimptomele bolii\r\n\r\n\r\n\tPrincipalele semne, de\u0219i nu sunt obligatorii a cancerului vezicii urinare sunt: apari\u021bia s\u00e2ngelui \u00een urin\u0103 \u0219i urinare dureroas\u0103 frecvent\u0103.\r\n\r\nConcentrare pe simptome?\r\n\r\n\r\n\tNu! Cu siguran\u021b\u0103 \u201castfel de simptome nu se merit\u0103 de a\u0219teptat\u201d \u2013\u00a0 90% dintre persoanele care au ca simptom clinic prezen\u021ba s\u00e2ngelui \u00een urin\u0103, nu sunt bolnavi de cancer al vezicii urinare. \u00cens\u0103 ignorarea acestui fapt duce la anxietate \u0219i la stres sever fiec\u0103rei persoane.\r\n\r\nExclude\u021bi suspiciunile\r\n\r\n\r\n\tPentru prima dat\u0103 \u00een Moldova, \u00een centrul medical ALFA diagnostica a fost implementat cu succes testul - Xpert Bladder Cancer Detection pentru detectarea cancerului vezicii urinare. Tehnologia patentat\u0103\u00a0 se bazeaz\u0103 pe determinarea \u00een urin\u0103 a cinci markeri moleculari dovedi\u021bi ai cancerului cu un grad sc\u0103zut \u0219i \u00eenalt de agresivitate.\r\n\r\nValoarea special\u0103 a testului este c\u0103 rezultatul s\u0103u negativ\r\nindic\u0103 absen\u021ba cancerului cu o probabilitate de 98%!\r\n\u00a0\r\nDe asemenea, testul poate detecta recidive la pacien\u021bii care au avut deja cancer de vezic\u0103 urinar\u0103. Timpul s\u0103u de execu\u021bie este de doar 3 ore! Testul se efectueaz\u0103 din urin\u0103 \u0219i nu necesit\u0103 preg\u0103tire special\u0103. Pre\u021bul testului \u2013 4000 lei.\u00a0\r\n\u00a0\r\nIMPORTANT!\r\n\r\n\r\n\tPacien\u021bilor, ce l-i sa prelevat urina pentru analiz\u0103 \u00een laboratorul central de pe strada N. Testemi\u021banu, 21, primesc rezultatul \u00een timp de 3 ore, \u00een filialele laboratorului din Chi\u0219in\u0103u \u2013 \u00een aceia\u0219i zi, filiala din B\u0103l\u021bi \u2013 a doua zi.\r\n\r\n\r\n\u00a0","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/450\/1","url":"\/ro\/magazine\/sange-in-urina.-tumoare-a-vezicii-urinare-450","url_full":"https:\/\/alfalab.md\/ro\/magazine\/sange-in-urina.-tumoare-a-vezicii-urinare-450","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/sange-in-urina.-tumoare-a-vezicii-urinare-450","show_startdate_d":"","show_enddate_d":"","date_d":"2019-12-13","show_startdate_text":"","show_enddate_text":"","date_text":"2019-12-13","date_day":"13","date_month":"Decembrie","date_published":"2021-11-18","date_modify":"2021-11-18","image_id":"191","image_ids":["191"],"image_url":"\/files\/getfile\/191\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/191\/","activegallery":[{"id":"242","parentclass":"magazine","idparentclass":"450","order":"1","idfile":"191","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/191\/","name":"52.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"441","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1568192400","views":null,"showonhome":"1","magazinetype":"2","name":"\u0414\u043b\u044f \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u044b\u0445 \u0438 \u0442\u043e\u043b\u044c\u043a\u043e \u043f\u043b\u0430\u043d\u0438\u0440\u0443\u044e\u0449\u0438\u0445. \u0427\u0442\u043e\u0431\u044b \u0432\u0441\u0435 \u0431\u044b\u043b\u043e \u0445\u043e\u0440\u043e\u0448\u043e.","author":"author blog meta","info":null,"title":"\u0414\u043b\u044f \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u044b\u0445 \u0438 \u0442\u043e\u043b\u044c\u043a\u043e \u043f\u043b\u0430\u043d\u0438\u0440\u0443\u044e\u0449\u0438\u0445. \u0427\u0442\u043e\u0431\u044b \u0432\u0441\u0435 \u0431\u044b\u043b\u043e \u0445\u043e\u0440\u043e\u0448\u043e.","urlsuffix":null,"description":"<h3>\u041d\u0435 \u0432\u044b\u043d\u0430\u0448\u0438\u0432\u0430\u043d\u0438\u0435 \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u0438, \u043f\u0440\u0435\u0436\u0434\u0435\u0432\u0440\u0435\u043c\u0435\u043d\u043d\u044b\u0435 \u0440\u043e\u0434\u044b, \u0442\u043e\u043a\u0441\u0438\u043a\u043e\u0437\u044b \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u0438, \u0433\u0438\u0431\u0435\u043b\u044c \u043f\u043b\u043e\u0434\u0430, \u043d\u0435\u0443\u0434\u0430\u0447\u043d\u044b\u0435 \u043f\u043e\u043f\u044b\u0442\u043a\u0438 \u042d\u041a\u041e, \u0442\u0440\u043e\u043c\u0431\u043e\u0437\u044b \u0432\u0435\u043d \u0433\u043e\u043b\u0435\u043d\u0438 \u0438 \u0442.\u0434.<\/h3>\n\u0422\u0430\u043a \u043a\u0430\u043a \u0432 \u043e\u0441\u043d\u043e\u0432\u0435 \u044d\u0442\u0438\u0445 \u0441\u0435\u0440\u044c\u0435\u0437\u043d\u044b\u0445 \u043f\u0440\u043e\u0431\u043b\u0435\u043c \u0447\u0430\u0441\u0442\u043e \u043b\u0435\u0436\u0430\u0442 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u044f \u0432 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0435, \u044d\u0442\u0438 \u043f\u0440\u043e\u0431\u043b\u0435\u043c\u044b \u0441\u0442\u0430\u043b\u043e \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u044b\u043c \u043f\u0440\u0435\u0434\u0432\u0438\u0434\u0435\u0442\u044c \u0441 \u043f\u043e\u043c\u043e\u0449\u044c\u044e \u0441\u043f\u0435\u0446\u0438\u0430\u043b\u044c\u043d\u044b\u0445 \u0442\u0435\u0441\u0442\u043e\u0432, \u0430 \u0437\u043d\u0430\u0447\u0438\u0442, \u0441\u0434\u0435\u043b\u0430\u0442\u044c \u0432\u0441\u0435 \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e\u0435, \u0447\u0442\u043e\u0431\u044b \u0438\u0445 \u043f\u0440\u0435\u0434\u043e\u0442\u0432\u0440\u0430\u0442\u0438\u0442\u044c.\u00a0\u0413\u0435\u043d\u0435\u0442\u0438\u043a\u0430 \u043f\u0435\u0440\u0435\u0441\u0442\u0430\u0435\u0442 \u0431\u044b\u0442\u044c \u0447\u0435\u043c-\u0442\u043e \u00ab\u043d\u0435\u043f\u043e\u043d\u044f\u0442\u043d\u044b\u043c\u00bb, \u0442\u0435\u0441\u0442\u044b \u0441\u0442\u0430\u043d\u043e\u0432\u044f\u0442\u0441\u044f \u0434\u043e\u0441\u0442\u0443\u043f\u043d\u044b\u043c\u0438, \u0438\u0445 \u0447\u0430\u0441\u0442\u043e \u0440\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0443\u044e\u0442 \u0432\u0440\u0430\u0447\u0438, \u0434\u0430 \u0438 \u0441\u0430\u043c\u0438 \u0436\u0435\u043d\u0449\u0438\u043d\u044b, \u043d\u0435\u0440\u0435\u0434\u043a\u043e \u0441\u0430\u043c\u043e\u0441\u0442\u043e\u044f\u0442\u0435\u043b\u044c\u043d\u043e \u0441\u0435\u0431\u0435 \u0438\u0445 \u0437\u0430\u043a\u0430\u0437\u044b\u0432\u0430\u044e\u0442.\n\n<h3>\u0427\u0442\u043e \u0436\u0435 \u0443\u0437\u043d\u0430\u044e\u0442 \u0432\u0440\u0430\u0447\u0438 \u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0438\u0437 \u044d\u0442\u0438\u0445 \u0430\u043d\u0430\u043b\u0438\u0437\u043e\u0432?<\/strong><\/h3>\n\u041d\u0430\u043f\u0440\u0438\u043c\u0435\u0440,\u00a0\u0438\u0441\u0441\u043b\u0435\u0434\u0443\u0435\u0442\u0441\u044f \u0433\u0435\u043d F2. \n\u0422\u0430\u043a \u0432\u044b\u0433\u043b\u044f\u0434\u0438\u0442 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442:<\/em>\n\n<table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"width:696px;\" width=\"696\">\n\t<tbody>\n\t\t<tr>\n\t\t\t<td rowspan=\"2\">\u0413\u0435\u043d<\/strong><\/td>\n\t\t\t<td rowspan=\"2\">\u041f\u043e\u043b\u0438\u043c\u043e\u0440\u0444\u0438\u0437\u043c<\/strong><\/td>\n\t\t\t<td colspan=\"3\">\u041e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u043d\u044b\u0439 \u0433\u0435\u043d\u043e\u0442\u0438\u043f<\/strong><\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\u041d\u043e\u0440\u043c\u0430\u043b\u044c\u043d\u0430\u044f \n\t\t\t\u0433\u043e\u043c\u043e\u0437\u0438\u0433\u043e\u0442\u0430<\/td>\n\t\t\t<td>\u041c\u0443\u0442\u0430\u043d\u0442\u043d\u0430\u044f \n\t\t\t\u0433\u043e\u043c\u043e\u0437\u0438\u0433\u043e\u0442\u0430<\/td>\n\t\t\t<td>\u0413\u0435\u0442\u0435\u0440\u043e\u0437\u0438\u0433\u043e\u0442\u0430<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>F2<\/td>\n\t\t\t<td>20210 G\/A<\/td>\n\t\t\t<td>G\/G<\/strong><\/td>\n\t\t\t<td>A\/A<\/strong><\/td>\n\t\t\t<td>G\/A<\/strong><\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n\u0422\u0430\u043a \u0432\u044b\u0433\u043b\u044f\u0434\u0438\u0442 \u0438\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f:<\/em> \n\u0415\u0441\u043b\u0438 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d G\/G<\/strong>\n\n<ul>\n\t<li>\u042d\u0442\u043e\u0442 \u0433\u0435\u043d\u043e\u0442\u0438\u043f\u00a0\u041d\u0415 \u041f\u0420\u0415\u0414\u0420\u0410\u0421\u041f\u041e\u041b\u0410\u0413\u0410\u0415\u0422<\/strong>\u00a0\u043a \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u044e \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u0444\u0430\u043a\u0442\u043e\u0440\u0430 II (\u043f\u0440\u043e\u0442\u0440\u043e\u043c\u0431\u0438\u043d\u0430).<\/li>\n<\/ul>\n \n\u0415\u0441\u043b\u0438 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d <\/strong>A<\/strong>\/<\/strong>A<\/strong> \u0438\u043b\u0438 <\/strong>G<\/strong>\/<\/strong>A<\/strong>\n\n<ul>\n\t<li>\u042d\u0442\u0438 \u0433\u0435\u043d\u043e\u0442\u0438\u043f\u044b\u00a0\u041f\u0420\u0415\u0414\u0420\u0410\u0421\u041f\u041e\u041b\u0410\u0413\u0410\u042e\u0422<\/strong>\u00a0\u043a \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u044e \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u043f\u0440\u043e\u0442\u0440\u043e\u043c\u0431\u0438\u043d\u0430 \u0438\u00a0\u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u044e \u0440\u0438\u0441\u043a\u0430 \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u044f \u0442\u0440\u043e\u043c\u0431\u043e\u0432<\/strong>, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u0441\u043f\u0440\u043e\u0432\u043e\u0446\u0438\u0440\u043e\u0432\u0430\u043d \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u044c\u044e, \u043f\u0440\u0438\u0435\u043c\u043e\u043c \u043f\u0435\u0440\u043e\u0440\u0430\u043b\u044c\u043d\u044b\u0445 \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u043e\u0432, \u0433\u043e\u0440\u043c\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0439 \u0437\u0430\u043c\u0435\u0441\u0442\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0435\u0439, \u043a\u0443\u0440\u0435\u043d\u0438\u0435\u043c, \u0434\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0438\u043c\u043c\u043e\u0431\u0438\u043b\u0438\u0437\u0430\u0446\u0438\u0435\u0439 (\u043e\u0431\u0435\u0437\u0434\u0432\u0438\u0436\u0438\u0432\u0430\u043d\u0438\u0435\u043c)*<\/strong>.<\/li>\n<\/ul>\n*<\/em>\u0420\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0443\u0435\u0442\u0441\u044f \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0441\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u044b\u0445 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0435\u0439 \u043a\u043e\u0430\u0433\u0443\u043b\u043e\u0433\u0440\u0430\u043c\u043c\u044b, \u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0442\u0435\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 \u0431\u043b\u0438\u0436\u0430\u0439\u0448\u0438\u0445 \u0440\u043e\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u0438\u043a\u043e\u0432 \u0438 \u0434\u0440\u0443\u0433\u0438\u0435 \u043c\u0435\u0440\u043e\u043f\u0440\u0438\u044f\u0442\u0438\u044f.<\/em> \n \n\u041d\u0430\u043f\u0440\u0438\u043c\u0435\u0440,\u00a0\u0438\u0441\u0441\u043b\u0435\u0434\u0443\u0435\u0442\u0441\u044f \u0433\u0435\u043d MTHFR. \n\u0422\u0430\u043a \u0432\u044b\u0433\u043b\u044f\u0434\u0438\u0442 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442:<\/em>\n\n<table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"width:696px;\" width=\"696\">\n\t<tbody>\n\t\t<tr>\n\t\t\t<td rowspan=\"2\">\u0413\u0435\u043d<\/strong><\/td>\n\t\t\t<td rowspan=\"2\">\u041f\u043e\u043b\u0438\u043c\u043e\u0440\u0444\u0438\u0437\u043c<\/strong><\/td>\n\t\t\t<td colspan=\"3\">\u041e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u043d\u044b\u0439 \u0433\u0435\u043d\u043e\u0442\u0438\u043f<\/strong><\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\u041d\u043e\u0440\u043c\u0430\u043b\u044c\u043d\u0430\u044f \n\t\t\t\u0433\u043e\u043c\u043e\u0437\u0438\u0433\u043e\u0442\u0430<\/td>\n\t\t\t<td>\u041c\u0443\u0442\u0430\u043d\u0442\u043d\u0430\u044f \n\t\t\t\u0433\u043e\u043c\u043e\u0437\u0438\u0433\u043e\u0442\u0430<\/td>\n\t\t\t<td>\u0413\u0435\u0442\u0435\u0440\u043e\u0437\u0438\u0433\u043e\u0442\u0430<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>MTHFR<\/td>\n\t\t\t<td>677 C\/T<\/td>\n\t\t\t<td>C\/C<\/strong><\/td>\n\t\t\t<td>T\/T<\/strong><\/td>\n\t\t\t<td>C\/T<\/strong><\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n\u0422\u0430\u043a \u0432\u044b\u0433\u043b\u044f\u0434\u0438\u0442 \u0438\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f:<\/em> \n\u0415\u0441\u043b\u0438 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d \u0421\/\u0421<\/strong> \n \n\u2022 \u042d\u0442\u043e\u0442 \u0433\u0435\u043d\u043e\u0442\u0438\u043f\u00a0\u041d\u0415 \u041f\u0420\u0415\u0414\u0420\u0410\u0421\u041f\u041e\u041b\u0410\u0413\u0410\u0415\u0422<\/strong>\u00a0\u043a \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u044e \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 MTHFR (\u043c\u0435\u0442\u0438\u043b\u0435\u043d\u0442\u0435\u0442\u0440\u0430\u0433\u0438\u0434\u0440\u043e\u0444\u043e\u043b\u0430\u0442\u0440\u0435\u0434\u0443\u043a\u0442\u0430\u0437\u044b). \n \n\u0415\u0441\u043b\u0438 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u044b \u0422\/\u0422 \u0438\u043b\u0438 \u0421\/\u0422<\/strong> \n \n\u2022 \u042d\u0442\u0438 \u0433\u0435\u043d\u043e\u0442\u0438\u043f\u044b\u00a0\u041f\u0420\u0415\u0414\u0420\u0410\u0421\u041f\u041e\u041b\u0410\u0413\u0410\u042e\u0422<\/strong>\u00a0\u043a \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u044e \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 MTHFR (\u043c\u0435\u0442\u0438\u043b\u0435\u043d\u0442\u0435\u0442\u0440\u0430\u0433\u0438\u0434\u0440\u043e\u0444\u043e\u043b\u0430\u0442\u0440\u0435\u0434\u0443\u043a\u0442\u0430\u0437\u044b) \u0434\u043e 60% \u043e\u0442 \u0441\u0440\u0435\u0434\u043d\u0435\u0433\u043e \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044f,\u00a0\u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u044e \u0440\u0438\u0441\u043a\u0430 \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u044f \u0442\u0440\u043e\u043c\u0431\u043e\u0432, \u0443\u0441\u0438\u043b\u0435\u043d\u0438\u044e \u043c\u0443\u0442\u0430\u0433\u0435\u043d\u043d\u043e\u0433\u043e \u0438 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\u043a\u043e\u0442\u043e\u0440\u043e\u0435 \u043f\u043e\u043c\u043e\u0436\u0435\u0442 \u0440\u0430\u0437\u043e\u0431\u0440\u0430\u0442\u044c\u0441\u044f \u0432 \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0436\u0434\u0435\u043d\u0438\u0438 \u0440\u0435\u0430\u043b\u044c\u043d\u044b\u0445<\/strong>\u00a0\u0438\u043b\u0438 \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u044b\u0445 \u0432 \u0431\u0443\u0434\u0443\u0449\u0435\u043c, \u043f\u0440\u043e\u0431\u043b\u0435\u043c.<\/strong>","description_clear":"\u041d\u0435 \u0432\u044b\u043d\u0430\u0448\u0438\u0432\u0430\u043d\u0438\u0435 \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u0438, \u043f\u0440\u0435\u0436\u0434\u0435\u0432\u0440\u0435\u043c\u0435\u043d\u043d\u044b\u0435 \u0440\u043e\u0434\u044b, \u0442\u043e\u043a\u0441\u0438\u043a\u043e\u0437\u044b \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u0438, \u0433\u0438\u0431\u0435\u043b\u044c \u043f\u043b\u043e\u0434\u0430, \u043d\u0435\u0443\u0434\u0430\u0447\u043d\u044b\u0435 \u043f\u043e\u043f\u044b\u0442\u043a\u0438 \u042d\u041a\u041e, \u0442\u0440\u043e\u043c\u0431\u043e\u0437\u044b \u0432\u0435\u043d \u0433\u043e\u043b\u0435\u043d\u0438 \u0438 \u0442.\u0434.\n\u0422\u0430\u043a \u043a\u0430\u043a \u0432 \u043e\u0441\u043d\u043e\u0432\u0435 \u044d\u0442\u0438\u0445 \u0441\u0435\u0440\u044c\u0435\u0437\u043d\u044b\u0445 \u043f\u0440\u043e\u0431\u043b\u0435\u043c \u0447\u0430\u0441\u0442\u043e \u043b\u0435\u0436\u0430\u0442 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u044f \u0432 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0435, \u044d\u0442\u0438 \u043f\u0440\u043e\u0431\u043b\u0435\u043c\u044b \u0441\u0442\u0430\u043b\u043e \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u044b\u043c \u043f\u0440\u0435\u0434\u0432\u0438\u0434\u0435\u0442\u044c \u0441 \u043f\u043e\u043c\u043e\u0449\u044c\u044e \u0441\u043f\u0435\u0446\u0438\u0430\u043b\u044c\u043d\u044b\u0445 \u0442\u0435\u0441\u0442\u043e\u0432, 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\u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0441\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u044b\u0445 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0435\u0439 \u043a\u043e\u0430\u0433\u0443\u043b\u043e\u0433\u0440\u0430\u043c\u043c\u044b, \u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0442\u0435\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 \u0431\u043b\u0438\u0436\u0430\u0439\u0448\u0438\u0445 \u0440\u043e\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u0438\u043a\u043e\u0432 \u0438 \u0434\u0440\u0443\u0433\u0438\u0435 \u043c\u0435\u0440\u043e\u043f\u0440\u0438\u044f\u0442\u0438\u044f.\n\n\u041d\u0430\u043f\u0440\u0438\u043c\u0435\u0440,\u00a0\u0438\u0441\u0441\u043b\u0435\u0434\u0443\u0435\u0442\u0441\u044f \u0433\u0435\u043d MTHFR.\n\u0422\u0430\u043a \u0432\u044b\u0433\u043b\u044f\u0434\u0438\u0442 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442:\n\n\n\t\n\t\t\n\t\t\t\u0413\u0435\u043d\n\t\t\t\u041f\u043e\u043b\u0438\u043c\u043e\u0440\u0444\u0438\u0437\u043c\n\t\t\t\u041e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u043d\u044b\u0439 \u0433\u0435\u043d\u043e\u0442\u0438\u043f\n\t\t\n\t\t\n\t\t\t\u041d\u043e\u0440\u043c\u0430\u043b\u044c\u043d\u0430\u044f\n\t\t\t\u0433\u043e\u043c\u043e\u0437\u0438\u0433\u043e\u0442\u0430\n\t\t\t\u041c\u0443\u0442\u0430\u043d\u0442\u043d\u0430\u044f\n\t\t\t\u0433\u043e\u043c\u043e\u0437\u0438\u0433\u043e\u0442\u0430\n\t\t\t\u0413\u0435\u0442\u0435\u0440\u043e\u0437\u0438\u0433\u043e\u0442\u0430\n\t\t\n\t\t\n\t\t\tMTHFR\n\t\t\t677 C\/T\n\t\t\tC\/C\n\t\t\tT\/T\n\t\t\tC\/T\n\t\t\n\t\n\n\u0422\u0430\u043a \u0432\u044b\u0433\u043b\u044f\u0434\u0438\u0442 \u0438\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f:\n\u0415\u0441\u043b\u0438 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d \u0421\/\u0421\n\n\u2022 \u042d\u0442\u043e\u0442 \u0433\u0435\u043d\u043e\u0442\u0438\u043f\u00a0\u041d\u0415 \u041f\u0420\u0415\u0414\u0420\u0410\u0421\u041f\u041e\u041b\u0410\u0413\u0410\u0415\u0422\u00a0\u043a \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u044e \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 MTHFR (\u043c\u0435\u0442\u0438\u043b\u0435\u043d\u0442\u0435\u0442\u0440\u0430\u0433\u0438\u0434\u0440\u043e\u0444\u043e\u043b\u0430\u0442\u0440\u0435\u0434\u0443\u043a\u0442\u0430\u0437\u044b).\n\n\u0415\u0441\u043b\u0438 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u044b \u0422\/\u0422 \u0438\u043b\u0438 \u0421\/\u0422\n\n\u2022 \u042d\u0442\u0438 \u0433\u0435\u043d\u043e\u0442\u0438\u043f\u044b\u00a0\u041f\u0420\u0415\u0414\u0420\u0410\u0421\u041f\u041e\u041b\u0410\u0413\u0410\u042e\u0422\u00a0\u043a \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u044e \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 MTHFR (\u043c\u0435\u0442\u0438\u043b\u0435\u043d\u0442\u0435\u0442\u0440\u0430\u0433\u0438\u0434\u0440\u043e\u0444\u043e\u043b\u0430\u0442\u0440\u0435\u0434\u0443\u043a\u0442\u0430\u0437\u044b) \u0434\u043e 60% \u043e\u0442 \u0441\u0440\u0435\u0434\u043d\u0435\u0433\u043e \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044f,\u00a0\u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u044e \u0440\u0438\u0441\u043a\u0430 \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u044f \u0442\u0440\u043e\u043c\u0431\u043e\u0432, \u0443\u0441\u0438\u043b\u0435\u043d\u0438\u044e \u043c\u0443\u0442\u0430\u0433\u0435\u043d\u043d\u043e\u0433\u043e \u0438 \u0442\u0435\u0440\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u043e\u0433\u043e \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f, \u043a\u043e\u0442\u043e\u0440\u043e\u0435 \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u0441\u043f\u0440\u043e\u0432\u043e\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u043e \u043d\u0438\u0437\u043a\u0438\u043c \u0441\u043e\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u0435\u043c \u0444\u043e\u043b\u0430\u0442\u043e\u0432 \u0432 \u043f\u0438\u0449\u0435, \u043a\u0443\u0440\u0435\u043d\u0438\u0435\u043c, \u0430\u043b\u043a\u043e\u0433\u043e\u043b\u0435\u043c.\n\n\n\u041c\u044b \u043f\u0440\u0435\u0434\u043b\u0430\u0433\u0430\u0435\u043c \u043a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u043d\u043e\u0435\u00a0\u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435\u00a012\u00a0\u0433\u0435\u043d\u043e\u0432, \u043a\u043e\u0442\u043e\u0440\u043e\u0435 \u043f\u043e\u043c\u043e\u0436\u0435\u0442 \u0440\u0430\u0437\u043e\u0431\u0440\u0430\u0442\u044c\u0441\u044f \u0432 \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0436\u0434\u0435\u043d\u0438\u0438 \u0440\u0435\u0430\u043b\u044c\u043d\u044b\u0445\u00a0\u0438\u043b\u0438 \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u044b\u0445 \u0432 \u0431\u0443\u0434\u0443\u0449\u0435\u043c, \u043f\u0440\u043e\u0431\u043b\u0435\u043c.","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/441\/1","url":"\/ro\/magazine\/dlya-beremennyx-i-tolko-planiruyushhix.-chtoby-vse-bylo-xorosho.-441","url_full":"https:\/\/alfalab.md\/ro\/magazine\/dlya-beremennyx-i-tolko-planiruyushhix.-chtoby-vse-bylo-xorosho.-441","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/dlya-beremennyx-i-tolko-planiruyushhix.-chtoby-vse-bylo-xorosho.-441","show_startdate_d":"","show_enddate_d":"","date_d":"2019-09-11","show_startdate_text":"","show_enddate_text":"","date_text":"2019-09-11","date_day":"11","date_month":"Septembrie","date_published":"2021-11-17","date_modify":"2021-11-17","image_id":"189","image_ids":["189"],"image_url":"\/files\/getfile\/189\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/189\/","activegallery":[{"id":"240","parentclass":"magazine","idparentclass":"441","order":"1","idfile":"189","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/189\/","name":"43.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"439","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1550656800","views":null,"showonhome":"1","magazinetype":"2","name":"A L E X \u2013 primul test alergologic din lume bazat pe nanotehnologie","author":"author blog meta","info":null,"title":"A L E X \u2013 primul test alergologic din lume bazat pe nanotehnologie","urlsuffix":null,"description":"OPORTUNIT\u0102\u021aI DIAGNOSTICE AST\u0102ZI<\/span> \r\n\u00a0 \r\nUn diagnostic alergologic, pe l\u00e2ng\u0103 colectarea unei anamneze \u0219i analizarea pl\u00e2ngerilor pacientului, ar fi imposibil f\u0103r\u0103 efectuarea testelor de laborator de \u00eenalt\u0103 calitate. Cu p\u0103rere de r\u0103u, testele alergologice recomandate la moment, au unele imperfec\u021biuni: num\u0103r mic de alergeni analiza\u021bi (de la 10 p\u00e2n\u0103 la 50), sensibilitate sc\u0103zut\u0103, un num\u0103r mare de rezultate fals pozitive cauzat de reac\u021biile \u00eencruci\u0219ate (la fiecare al 4-lea pacient!). \r\n \r\nCa urmare, ob\u021binem rezultate false sau incomplete, cre\u00e2nd \u00een continuare impedimente \u00een stabilirea unei conduite terapeutice.<\/strong> \r\n\u00a0 \r\nSOLU\u021aIA MULT A\u0218TEPTAT\u0102<\/span> \r\n\u00a0 \r\nTestul alergologic ALEX este lipsit de aceste \u201dimperfec\u021biuni\u201d. Este primul test alergologic multiplex, cu o sensibilitate \u0219i selectivitate mai mare comparativ cu testele tradi\u021bionale \u0219i permite m\u0103surarea simultan\u0103 a IgE total \u0219i anticorpi specifice IgE fa\u0163\u0103 de o serie de extracte de alergeni \u015fi alergeni moleculari. Acest test cuprinde 122 de componente alergenice moleculare \u0219i 160 de extracte alergenice diferite (un panel de 282 alergeni!). Indiferent de v\u00e2rst\u0103, o cantitate foarte redus\u0103 de s\u00e2nge este suficient\u0103 pentru un screening complet al alergiilor. \r\n\u00a0 \r\nMedicii alergologi au fost \u00een a\u0219teptarea unii astfel de instrument de diagnostic, care ar combina \u00een sine nivele doi \u0219i trei de diagnostic alergologic. Acest test va permite de a aprecia integral sensibilizarea organismului pacientului \u0219i de a stabili o conduit\u0103 terapeutic\u0103 individualizat\u0103. \r\n\u00a0 \r\nTestul alergologic ALEX bazat pe tehnologia cu nano-particule (multiplex nano-bead technology) a fost elaborat de c\u0103tre speciali\u0219tii companiei Macro Array Diagnostics (Viena, \u0410ustria).<\/span><\/strong> \r\n\u00a0 \r\nDetaliile despre testul ALEX \u2013 pe site-ul nostru specializat <a href=\"https:\/\/alex.alergie.md\/index.html\">www.alergie.md<\/span><\/a>","description_clear":"OPORTUNIT\u0102\u021aI DIAGNOSTICE AST\u0102ZI\r\n\u00a0\r\nUn diagnostic alergologic, pe l\u00e2ng\u0103 colectarea unei anamneze \u0219i analizarea pl\u00e2ngerilor pacientului, ar fi imposibil f\u0103r\u0103 efectuarea testelor de laborator de \u00eenalt\u0103 calitate. Cu p\u0103rere de r\u0103u, testele alergologice recomandate la moment, au unele imperfec\u021biuni: num\u0103r mic de alergeni analiza\u021bi (de la 10 p\u00e2n\u0103 la 50), sensibilitate sc\u0103zut\u0103, un num\u0103r mare de rezultate fals pozitive cauzat de reac\u021biile \u00eencruci\u0219ate (la fiecare al 4-lea pacient!).\r\n\r\nCa urmare, ob\u021binem rezultate false sau incomplete, cre\u00e2nd \u00een continuare impedimente \u00een stabilirea unei conduite terapeutice.\r\n\u00a0\r\nSOLU\u021aIA MULT A\u0218TEPTAT\u0102\r\n\u00a0\r\nTestul alergologic ALEX este lipsit de aceste \u201dimperfec\u021biuni\u201d. Este primul test alergologic multiplex, cu o sensibilitate \u0219i selectivitate mai mare comparativ cu testele tradi\u021bionale \u0219i permite m\u0103surarea simultan\u0103 a IgE total \u0219i anticorpi specifice IgE fa\u0163\u0103 de o serie de extracte de alergeni \u015fi alergeni moleculari. Acest test cuprinde 122 de componente alergenice moleculare \u0219i 160 de extracte alergenice diferite (un panel de 282 alergeni!). Indiferent de v\u00e2rst\u0103, o cantitate foarte redus\u0103 de s\u00e2nge este suficient\u0103 pentru un screening complet al alergiilor.\r\n\u00a0\r\nMedicii alergologi au fost \u00een a\u0219teptarea unii astfel de instrument de diagnostic, care ar combina \u00een sine nivele doi \u0219i trei de diagnostic alergologic. Acest test va permite de a aprecia integral sensibilizarea organismului pacientului \u0219i de a stabili o conduit\u0103 terapeutic\u0103 individualizat\u0103.\r\n\u00a0\r\nTestul alergologic ALEX bazat pe tehnologia cu nano-particule (multiplex nano-bead technology) a fost elaborat de c\u0103tre speciali\u0219tii companiei Macro Array Diagnostics (Viena, \u0410ustria).\r\n\u00a0\r\nDetaliile despre testul ALEX \u2013 pe site-ul nostru specializat www.alergie.md","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/439\/1","url":"\/ro\/magazine\/a-l-e-x-primul-test-alergologic-din-lume-bazat-pe-nanotehnologie-439","url_full":"https:\/\/alfalab.md\/ro\/magazine\/a-l-e-x-primul-test-alergologic-din-lume-bazat-pe-nanotehnologie-439","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/a-l-e-x-primul-test-alergologic-din-lume-bazat-pe-nanotehnologie-439","show_startdate_d":"","show_enddate_d":"","date_d":"2019-02-20","show_startdate_text":"","show_enddate_text":"","date_text":"2019-02-20","date_day":"20","date_month":"Februarie","date_published":"2021-11-17","date_modify":"2021-11-17","image_id":"187","image_ids":["187"],"image_url":"\/files\/getfile\/187\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/187\/","activegallery":[{"id":"238","parentclass":"magazine","idparentclass":"439","order":"1","idfile":"187","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/187\/","name":"41.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"438","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1546509600","views":null,"showonhome":"1","magazinetype":"2","name":"Iar acum \u0219i ei sunt o epidemie","author":"author blog meta","info":null,"title":"Iar acum \u0219i ei sunt o epidemie","urlsuffix":null,"description":"P\u00e2n\u0103 nu demult termenul de boli autoimune (BA) era cunoscut doar unui cerc restr\u00e2ns de speciali\u0219ti. La momentul actual savan\u021bii le numesc epidemie, chiar dac\u0103 pentru mul\u021bi dintre noi acest termen se asociaz\u0103 de obicei cu infec\u021biile. O cre\u0219tere vertiginoas\u0103 al BA \u00een ultimii zece ani se constat\u0103 ca o consecin\u021b\u0103 al \u201defectelor adverse ale civiliza\u021biei\u201d: ecologie, fastfood, superigien\u0103, cre\u0219terea \u201dsterilit\u0103\u021bii\u201d mediului intern al organismului din cauza administr\u0103rii antibioticelor pentru orice problem\u0103. \u0218i iar\u0103\u0219i, st\u0103rile de stres. \r\n \r\nSensul profund al BA poate fi explicat astfel \u2013 organismul nu mai poate recunoa\u0219te ce e \u201dal lui\u201d \u0219i ce e \u201dstr\u0103in\u201d. De aceea se atac\u0103 pe el \u00eensu\u0219i.<\/em> \r\n \r\nSunt greu de recunoscut<\/strong><\/span> \r\n \r\nEste greu de suspectat BA din cauza multitudinii de simptomatologie necaracteristic\u0103. Nu are rost s\u0103 le enumer\u0103m. \r\n \r\nNu cru\u021b\u0103 nici un organ<\/span><\/strong> \r\n \r\nGlanda tiroid\u0103, articula\u021biile, miocardul, conjunctiva, sistemul nervos \u2013 lista poate fi continuat\u0103, dar iar\u0103\u0219i f\u0103r\u0103 nici un rost. \r\n \r\n\u0218i denumirea este neclar\u0103<\/span><\/strong> \r\n \r\nSclerodermie, polimiozit\u0103, lupus, vasculit\u0103 granulomatoas\u0103, artrit\u0103 reumatoid\u0103 \u2013 sigur nu merit\u0103 s\u0103 memor\u0103m aceste denumiri. \r\n \r\nCe trebuie de f\u0103cut<\/span><\/strong> \r\n \r\n\u00cen fiecare caz \u00een care doctorul dumneavoastr\u0103 sau dumneavoastr\u0103 v\u0103 confrunta\u021bi cu un diagnostic dificil - trebuie s\u0103 treci doar c\u00e2teva teste de laborator pentru BA. F\u0103r\u0103 exagerare - acest lucru poate clarifica complet situa\u021bia. \r\n \r\nDe exemplu, dup\u0103 ce a\u021bi testat a\u0219a numitul <a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/S\/screening-anticorpi-antinucleari-igg-substratul-hep-2-372\">factorul antinuclear<\/span><\/a><\/em> (biochip tehnologiie) de 300 lei, \u201ddin zbor\u201d pot fi excluse o serie de boli autoimune sistemice! \r\n \r\nC\u00c2TEVA CUVINTE DESPRE NOI<\/span><\/strong> \r\n \r\nDepartamentul diagnosticului imunologic al laboratorului ALFA diagnostica zilnic execut\u0103 cercet\u0103ri comlexe care scot la lumin\u0103 tainele clinice nedeslu\u0219ite anterior.","description_clear":"P\u00e2n\u0103 nu demult termenul de boli autoimune (BA) era cunoscut doar unui cerc restr\u00e2ns de speciali\u0219ti. La momentul actual savan\u021bii le numesc epidemie, chiar dac\u0103 pentru mul\u021bi dintre noi acest termen se asociaz\u0103 de obicei cu infec\u021biile. O cre\u0219tere vertiginoas\u0103 al BA \u00een ultimii zece ani se constat\u0103 ca o consecin\u021b\u0103 al \u201defectelor adverse ale civiliza\u021biei\u201d: ecologie, fastfood, superigien\u0103, cre\u0219terea \u201dsterilit\u0103\u021bii\u201d mediului intern al organismului din cauza administr\u0103rii antibioticelor pentru orice problem\u0103. \u0218i iar\u0103\u0219i, st\u0103rile de stres.\r\n\r\nSensul profund al BA poate fi explicat astfel \u2013 organismul nu mai poate recunoa\u0219te ce e \u201dal lui\u201d \u0219i ce e \u201dstr\u0103in\u201d. De aceea se atac\u0103 pe el \u00eensu\u0219i.\r\n\r\nSunt greu de recunoscut\r\n\r\nEste greu de suspectat BA din cauza multitudinii de simptomatologie necaracteristic\u0103. Nu are rost s\u0103 le enumer\u0103m.\r\n\r\nNu cru\u021b\u0103 nici un organ\r\n\r\nGlanda tiroid\u0103, articula\u021biile, miocardul, conjunctiva, sistemul nervos \u2013 lista poate fi continuat\u0103, dar iar\u0103\u0219i f\u0103r\u0103 nici un rost.\r\n\r\n\u0218i denumirea este neclar\u0103\r\n\r\nSclerodermie, polimiozit\u0103, lupus, vasculit\u0103 granulomatoas\u0103, artrit\u0103 reumatoid\u0103 \u2013 sigur nu merit\u0103 s\u0103 memor\u0103m aceste denumiri.\r\n\r\nCe trebuie de f\u0103cut\r\n\r\n\u00cen fiecare caz \u00een care doctorul dumneavoastr\u0103 sau dumneavoastr\u0103 v\u0103 confrunta\u021bi cu un diagnostic dificil - trebuie s\u0103 treci doar c\u00e2teva teste de laborator pentru BA. F\u0103r\u0103 exagerare - acest lucru poate clarifica complet situa\u021bia.\r\n\r\nDe exemplu, dup\u0103 ce a\u021bi testat a\u0219a numitul factorul antinuclear (biochip tehnologiie) de 300 lei, \u201ddin zbor\u201d pot fi excluse o serie de boli autoimune sistemice!\r\n\r\nC\u00c2TEVA CUVINTE DESPRE NOI\r\n\r\nDepartamentul diagnosticului imunologic al laboratorului ALFA diagnostica zilnic execut\u0103 cercet\u0103ri comlexe care scot la lumin\u0103 tainele clinice nedeslu\u0219ite anterior.","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/438\/1","url":"\/ro\/magazine\/iar-acum-si-ei-sunt-o-epidemie-438","url_full":"https:\/\/alfalab.md\/ro\/magazine\/iar-acum-si-ei-sunt-o-epidemie-438","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/iar-acum-si-ei-sunt-o-epidemie-438","show_startdate_d":"","show_enddate_d":"","date_d":"2019-01-03","show_startdate_text":"","show_enddate_text":"","date_text":"2019-01-03","date_day":"03","date_month":"Ianuarie","date_published":"2021-11-17","date_modify":"2021-11-17","image_id":"287","image_ids":["287"],"image_url":"\/files\/getfile\/287\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/287\/","activegallery":[{"id":"255","parentclass":"magazine","idparentclass":"438","order":"1","idfile":"287","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/287\/","name":"40.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"436","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1544176800","views":null,"showonhome":"1","magazinetype":"2","name":"PCA3 \u2013 panaceu? Nu! Dar avantajele sunt evidente.","author":"author blog meta","info":null,"title":"PCA3 \u2013 panaceu? Nu! Dar avantajele sunt evidente.","urlsuffix":null,"description":"Medicii urologi cunosc bine faptul c\u0103 este destul de dificil\u0103 interpretarea nivelurilor ridicate ale PSA. Dar mai ales b\u0103rba\u021bii c\u00e2t de \u00eengrijora\u021bi sunt la acest capitol. Nici mai mult, nici mai pu\u021bin, dar probabil poate fi vorba despre cancerul de prostat\u0103, care ocup\u0103 ferm locul 2, \u00een r\u00e2ndul maladiilor oncologice la b\u0103rba\u021bi. \r\n\u00a0 \r\nA\u0219adar, esen\u021ba \u00eentreb\u0103rii<\/strong><\/span> \r\nAtunci c\u00e2nd sunt detectate niveluri ridicate ale PSA> 4 ng\/ml, iar mai exact, de la 4 p\u00e2n\u0103 la 10 ng\/ml, \u00een fa\u021ba specialistului apare \u00eentrebarea \u2013 c\u0103rui fapt acest lucru se datoreaz\u0103? Nivelurile ridicate ale PSA sunt asociate cu: hiperplazia benign\u0103 (adenom) a prostate, proces inflamator, sau\u2026.cancer? Dup\u0103 un examen clinic minu\u021bios a pacientului, se regurge la biopsia prostatei, adic\u0103 se ob\u021bine fragmente de \u021besut prostatic (p\u00e2n\u0103 la 12) pentru examinare histopatologic\u0103, ca ulterior s\u0103 se confirme sau infirme presupunerile medicului. \r\n\u00a0 \r\nProcedura de biopsie este nepl\u0103cut\u0103 \u0219i traumatizant\u0103, dar nu exist\u0103 alt\u0103 solu\u021bie. Totodat\u0103, conform datelor statistice, biopsia confirm\u0103 diagnosticul presupus anterior doar \u00een fiecare al 4-lea caz. \u00cen alte 75 % \u2013 biopsia nu a fost necesar\u0103. Dar, \u00een momentul efectu\u0103rii biopsiei, acest lucru nu a fost cunoscut. \r\n\u00a0 \r\nDecizie<\/span><\/strong> \r\nDetectarea genei PCA3 \u2013 sus\u021bine cu o \u00eenalt\u0103 \u00eencredere necesitatea efectu\u0103rii punc\u021biei biopsie a prostatei. \r\n\u00a0 \r\nCe este PCA3?<\/span><\/strong> \r\nPCA3 sau <a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/A\/antigenul-cancerului-de-prostata-3-pca3-1845\">Prostate Cancer Antigen<\/span><\/a> \u2013 gen\u0103 care este activat\u0103 \u00een \u021besutul tumoral din prostat\u0103. Nu trebuie confundat\u0103 cu PSA \u2013 bine cunoscut\u0103 majorit\u0103\u021bii b\u0103rba\u021bilor, ca Antigenul Specific Prostatei, determinat \u00een s\u00e2nge. \r\nProdusul activ\u0103rii genei PCA 3 \u2013 ARN mesager, poate fi detectat \u00een urina ob\u021binut\u0103 dup\u0103 masajul prostatei. \u0218i \u00een dependen\u021b\u0103 de scorul PCA3 se va decide necesitatea efectu\u0103rii punc\u021biei biopsie a prostatei. Lu\u00e2nd \u00een considera\u021bie, bine\u00een\u021beles, toat\u0103 informa\u021bia despre pacient disponibil\u0103 medicului (v\u00e2rsta, datele examin\u0103rii la tu\u0219eul rectal, antecedentele eredo-colaterale, nivelul PSA \u0219i altele). \r\n\u00a0 \r\nPCA 3 \u2013 panaceu? Nu! Dar avantajele sunt evidente.<\/span><\/strong> \r\nF\u0103c\u00e2nd aceast\u0103 investiga\u021bie, p\u00e2n\u0103 la 60% dintre pacien\u021bi pot evita o biopsie inutil\u0103, de\u0219i \u00een acela\u0219i timp (conform datelor statistice) \u00een 1-2% cancerul de prostat\u0103 poate r\u0103m\u00e2ne nedetectabil. Din p\u0103cate, nu exist\u0103 \u00eenc\u0103 teste perfecte pentru detectarea cancerului de prostat\u0103.","description_clear":"Medicii urologi cunosc bine faptul c\u0103 este destul de dificil\u0103 interpretarea nivelurilor ridicate ale PSA. Dar mai ales b\u0103rba\u021bii c\u00e2t de \u00eengrijora\u021bi sunt la acest capitol. Nici mai mult, nici mai pu\u021bin, dar probabil poate fi vorba despre cancerul de prostat\u0103, care ocup\u0103 ferm locul 2, \u00een r\u00e2ndul maladiilor oncologice la b\u0103rba\u021bi.\r\n\u00a0\r\nA\u0219adar, esen\u021ba \u00eentreb\u0103rii\r\nAtunci c\u00e2nd sunt detectate niveluri ridicate ale PSA> 4 ng\/ml, iar mai exact, de la 4 p\u00e2n\u0103 la 10 ng\/ml, \u00een fa\u021ba specialistului apare \u00eentrebarea \u2013 c\u0103rui fapt acest lucru se datoreaz\u0103? Nivelurile ridicate ale PSA sunt asociate cu: hiperplazia benign\u0103 (adenom) a prostate, proces inflamator, sau\u2026.cancer? Dup\u0103 un examen clinic minu\u021bios a pacientului, se regurge la biopsia prostatei, adic\u0103 se ob\u021bine fragmente de \u021besut prostatic (p\u00e2n\u0103 la 12) pentru examinare histopatologic\u0103, ca ulterior s\u0103 se confirme sau infirme presupunerile medicului.\r\n\u00a0\r\nProcedura de biopsie este nepl\u0103cut\u0103 \u0219i traumatizant\u0103, dar nu exist\u0103 alt\u0103 solu\u021bie. Totodat\u0103, conform datelor statistice, biopsia confirm\u0103 diagnosticul presupus anterior doar \u00een fiecare al 4-lea caz. \u00cen alte 75 % \u2013 biopsia nu a fost necesar\u0103. Dar, \u00een momentul efectu\u0103rii biopsiei, acest lucru nu a fost cunoscut.\r\n\u00a0\r\nDecizie\r\nDetectarea genei PCA3 \u2013 sus\u021bine cu o \u00eenalt\u0103 \u00eencredere necesitatea efectu\u0103rii punc\u021biei biopsie a prostatei.\r\n\u00a0\r\nCe este PCA3?\r\nPCA3 sau Prostate Cancer Antigen \u2013 gen\u0103 care este activat\u0103 \u00een \u021besutul tumoral din prostat\u0103. Nu trebuie confundat\u0103 cu PSA \u2013 bine cunoscut\u0103 majorit\u0103\u021bii b\u0103rba\u021bilor, ca Antigenul Specific Prostatei, determinat \u00een s\u00e2nge.\r\nProdusul activ\u0103rii genei PCA 3 \u2013 ARN mesager, poate fi detectat \u00een urina ob\u021binut\u0103 dup\u0103 masajul prostatei. \u0218i \u00een dependen\u021b\u0103 de scorul PCA3 se va decide necesitatea efectu\u0103rii punc\u021biei biopsie a prostatei. Lu\u00e2nd \u00een considera\u021bie, bine\u00een\u021beles, toat\u0103 informa\u021bia despre pacient disponibil\u0103 medicului (v\u00e2rsta, datele examin\u0103rii la tu\u0219eul rectal, antecedentele eredo-colaterale, nivelul PSA \u0219i altele).\r\n\u00a0\r\nPCA 3 \u2013 panaceu? Nu! Dar avantajele sunt evidente.\r\nF\u0103c\u00e2nd aceast\u0103 investiga\u021bie, p\u00e2n\u0103 la 60% dintre pacien\u021bi pot evita o biopsie inutil\u0103, de\u0219i \u00een acela\u0219i timp (conform datelor statistice) \u00een 1-2% cancerul de prostat\u0103 poate r\u0103m\u00e2ne nedetectabil. Din p\u0103cate, nu exist\u0103 \u00eenc\u0103 teste perfecte pentru detectarea cancerului de prostat\u0103.","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/436\/1","url":"\/ro\/magazine\/pca3-panaceu-nu-dar-avantajele-sunt-evidente.-436","url_full":"https:\/\/alfalab.md\/ro\/magazine\/pca3-panaceu-nu-dar-avantajele-sunt-evidente.-436","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/pca3-panaceu-nu-dar-avantajele-sunt-evidente.-436","show_startdate_d":"","show_enddate_d":"","date_d":"2018-12-07","show_startdate_text":"","show_enddate_text":"","date_text":"2018-12-07","date_day":"07","date_month":"Decembrie","date_published":"2021-11-17","date_modify":"2021-11-17","image_id":"185","image_ids":["185"],"image_url":"\/files\/getfile\/185\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/185\/","activegallery":[{"id":"236","parentclass":"magazine","idparentclass":"436","order":"1","idfile":"185","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/185\/","name":"38.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"435","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1540807200","views":null,"showonhome":"1","magazinetype":"2","name":"De ce doare burta dup\u0103 lactate?","author":"author blog meta","info":null,"title":"De ce doare burta dup\u0103 lactate?","urlsuffix":null,"description":"Balonare, disconfort, senza\u021bie de grea\u021b\u0103, dereglarea defeca\u021biei \u2013 toate acestea sunt simptomele problemelor cu tractul gastro-intestinal. Dar de ce aceste simptome apar anume dup\u0103 consumul de lapte integral sau de produse lactate? \r\n\u00a0 \r\nCum ar trebui s\u0103 fie<\/strong> \r\nPentru ca lactoza (zah\u0103rul din lapte), componenta principal\u0103 a laptelui, s\u0103 fie asimilat\u0103 normal de organism, este necesar\u0103 o cantitate suficient\u0103 de enzim\u0103 special\u0103 \u2013 lactaz\u0103. \r\n\u00a0 \r\nIar dac\u0103 cantitatea de lactaz\u0103 nu este suficient\u0103?<\/strong> \r\nAceasta \u00eenseamn\u0103 c\u0103 un exces de lactoz\u0103 nedescompus\u0103 va nimeri \u00een intestin \u0219i va fi fermentat de bacterii. \u00cen rezultat apar toate acele simptome, despre care s-a vorbit mai sus. \r\n\u00a0 \r\nDe ce lactaza poate s\u0103 nu fie suficient\u0103?<\/strong> \r\nDin cauza unui defect genetic, care este destul de comun. A suspecta problema nu este dificil, dac\u0103 simptomele apar dup\u0103 consumul de lapte sau ca\u0219caval. \r\n\u00a0 \r\nCum poate fi confirmat\u0103 presupunerea?<\/strong> \r\nUn <a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/G\/genotiparea-msm6-intoleranta-la-lactoza-1824\">test genetic<\/span><\/a> special clarific\u0103 problema. Trebuie s\u0103 da\u021bi s\u00e2nge din ven\u0103, f\u0103r\u0103 ca s\u0103 fie necesar\u0103 careva preg\u0103tire, \u0219i peste 10 zile pute\u021bi ob\u021bine raportul, \u00een care se va indica dac\u0103 a fost sau nu depistat\u0103 o cauz\u0103 genetic\u0103. Pre\u021bul testului este de 400 lei.","description_clear":"Balonare, disconfort, senza\u021bie de grea\u021b\u0103, dereglarea defeca\u021biei \u2013 toate acestea sunt simptomele problemelor cu tractul gastro-intestinal. Dar de ce aceste simptome apar anume dup\u0103 consumul de lapte integral sau de produse lactate?\r\n\u00a0\r\nCum ar trebui s\u0103 fie\r\nPentru ca lactoza (zah\u0103rul din lapte), componenta principal\u0103 a laptelui, s\u0103 fie asimilat\u0103 normal de organism, este necesar\u0103 o cantitate suficient\u0103 de enzim\u0103 special\u0103 \u2013 lactaz\u0103.\r\n\u00a0\r\nIar dac\u0103 cantitatea de lactaz\u0103 nu este suficient\u0103?\r\nAceasta \u00eenseamn\u0103 c\u0103 un exces de lactoz\u0103 nedescompus\u0103 va nimeri \u00een intestin \u0219i va fi fermentat de bacterii. \u00cen rezultat apar toate acele simptome, despre care s-a vorbit mai sus.\r\n\u00a0\r\nDe ce lactaza poate s\u0103 nu fie suficient\u0103?\r\nDin cauza unui defect genetic, care este destul de comun. A suspecta problema nu este dificil, dac\u0103 simptomele apar dup\u0103 consumul de lapte sau ca\u0219caval.\r\n\u00a0\r\nCum poate fi confirmat\u0103 presupunerea?\r\nUn test genetic special clarific\u0103 problema. Trebuie s\u0103 da\u021bi s\u00e2nge din ven\u0103, f\u0103r\u0103 ca s\u0103 fie necesar\u0103 careva preg\u0103tire, \u0219i peste 10 zile pute\u021bi ob\u021bine raportul, \u00een care se va indica dac\u0103 a fost sau nu depistat\u0103 o cauz\u0103 genetic\u0103. Pre\u021bul testului este de 400 lei.","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/435\/1","url":"\/ro\/magazine\/de-ce-doare-burta-dupa-lactate-435","url_full":"https:\/\/alfalab.md\/ro\/magazine\/de-ce-doare-burta-dupa-lactate-435","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/de-ce-doare-burta-dupa-lactate-435","show_startdate_d":"","show_enddate_d":"","date_d":"2018-10-29","show_startdate_text":"","show_enddate_text":"","date_text":"2018-10-29","date_day":"29","date_month":"Octombrie","date_published":"2021-11-17","date_modify":"2021-11-17","image_id":"183","image_ids":["183"],"image_url":"\/files\/getfile\/183\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/183\/","activegallery":[{"id":"234","parentclass":"magazine","idparentclass":"435","order":"1","idfile":"183","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/183\/","name":"37.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"434","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1537779600","views":null,"showonhome":"1","magazinetype":"2","name":"Alergia la arahidele \u00eendr\u0103gite de mul\u021bi!","author":"author blog meta","info":null,"title":"Alergia la arahidele \u00eendr\u0103gite de mul\u021bi!","urlsuffix":null,"description":"Arahidele sunt \u00eendr\u0103gite dac\u0103 nu de to\u021bi, atunci de foarte mul\u021bi, cu siguran\u021b\u0103. \u00cen orice form\u0103. C\u0103ci ele sunt \u0219i folositoare, \u0219i gustoase. Dar, cu toate acestea, arahidele pot provoca reac\u021bii alergice, \u0219i nu doar sub form\u0103 de m\u00e2nc\u0103rime, urticarie, nas \u00eenfundat, str\u0103nut sau l\u0103crimare, dar \u0219i deosebit de periculoase pentru fiecare al 50-lea copil! \r\n\u00a0 \r\nAlergologii consider\u0103 c\u0103 circa 10% dintre copii sunt sensibili la arahide, iar la 1-2% dintre copii se pot dezvolta complica\u021bii severe, p\u00e2n\u0103 la \u0219oc anafilactic \u2013 o stare care pune \u00een pericol via\u021ba. Din p\u0103cate, \u0219i asemenea cazuri au loc. \r\n\u00a0 \r\nPersoanele alergice la arahide pot de asemenea reac\u021biona la alergenii de alune, pelin, mere, piersici, morcov, soia, kiwi, \u021belin\u0103, maz\u0103re, linte, prune. \r\n\u00a0 \r\nProblemele de diagnosticare<\/strong> \r\n\u00a0 \r\nTestele de screening la alergenii de arahide, oferite ast\u0103zi de laboratoare, de\u0219i sunt foarte valoroase, totu\u0219i nu ne permit s\u0103 r\u0103spundem la un \u00eentreg \u0219ir de \u00eentrb\u0103ri foarte importante. De exemplu, poate oare presupusa alergie la arahide s\u0103 fie \u201efals\u0103\u201d, adic\u0103 s\u0103 fie o consecin\u021b\u0103 a alergiilor \u00eencruci\u0219ate, de exemplu, la mesteac\u0103n sau la al\u021bi alergeni? Sau poate ea nu este deloc periculoas\u0103. Sau este at\u00e2t de periculoas\u0103, \u00eenc\u00e2t te po\u021bi doar uita la arahide, \u00een cel mai bun caz. \r\n\u00a0 \r\nPosibila problem\u0103 poate fi acum prev\u0103zut\u0103, deci \u0219i evitat\u0103!<\/strong> \r\n\u00a0 \r\nMedicina nu st\u0103 \u00een loc, \u0219i \u00een lume recent a ap\u0103rut un test molecular cu posibilit\u0103\u021bi noi, care permite s\u0103 se deosebeasc\u0103 alergia \u201ereal\u0103\u201d la arahide de cea \u201efals\u0103\u201d, s\u0103 se prezic\u0103 riscul de reac\u021bii severe (dac\u0103 acestea se vor dezvolta sau nu), s\u0103 se aleag\u0103 varianta optim\u0103 de imunoterapie, \u0219i s\u0103 se r\u0103spund\u0103 la \u00eentrebarea cum influen\u021beaz\u0103 prelucrarea termic\u0103 asupra alergenicit\u0103\u021bii arahidelor. Dup\u0103 cum spun exper\u021bii, diagnosticarea molecular\u0103 este \u201eperforman\u021ba de top\u201d \u00een alergologia modern\u0103. \r\n\u00a0 \r\nUnde se poate face analiza<\/strong> \r\n \r\nAst\u0103zi \u00een Republica Moldova diagnosticarea alergologic\u0103 molecular\u0103 pentru arahide este oferit\u0103 doar de laboratorul nostru ALFA diagnostica. Costul analizei este 700 de lei, dar informa\u021biile primite merit\u0103 ace\u0219ti bani. <a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/A\/alergeni-componente-moleculare-arahidelor-1782\">Mai multe<\/span><\/a> despre acest test pute\u021bi afla pe site-ul oficial al laboratorului.","description_clear":"Arahidele sunt \u00eendr\u0103gite dac\u0103 nu de to\u021bi, atunci de foarte mul\u021bi, cu siguran\u021b\u0103. \u00cen orice form\u0103. C\u0103ci ele sunt \u0219i folositoare, \u0219i gustoase. Dar, cu toate acestea, arahidele pot provoca reac\u021bii alergice, \u0219i nu doar sub form\u0103 de m\u00e2nc\u0103rime, urticarie, nas \u00eenfundat, str\u0103nut sau l\u0103crimare, dar \u0219i deosebit de periculoase pentru fiecare al 50-lea copil!\r\n\u00a0\r\nAlergologii consider\u0103 c\u0103 circa 10% dintre copii sunt sensibili la arahide, iar la 1-2% dintre copii se pot dezvolta complica\u021bii severe, p\u00e2n\u0103 la \u0219oc anafilactic \u2013 o stare care pune \u00een pericol via\u021ba. Din p\u0103cate, \u0219i asemenea cazuri au loc.\r\n\u00a0\r\nPersoanele alergice la arahide pot de asemenea reac\u021biona la alergenii de alune, pelin, mere, piersici, morcov, soia, kiwi, \u021belin\u0103, maz\u0103re, linte, prune.\r\n\u00a0\r\nProblemele de diagnosticare\r\n\u00a0\r\nTestele de screening la alergenii de arahide, oferite ast\u0103zi de laboratoare, de\u0219i sunt foarte valoroase, totu\u0219i nu ne permit s\u0103 r\u0103spundem la un \u00eentreg \u0219ir de \u00eentrb\u0103ri foarte importante. De exemplu, poate oare presupusa alergie la arahide s\u0103 fie \u201efals\u0103\u201d, adic\u0103 s\u0103 fie o consecin\u021b\u0103 a alergiilor \u00eencruci\u0219ate, de exemplu, la mesteac\u0103n sau la al\u021bi alergeni? Sau poate ea nu este deloc periculoas\u0103. Sau este at\u00e2t de periculoas\u0103, \u00eenc\u00e2t te po\u021bi doar uita la arahide, \u00een cel mai bun caz.\r\n\u00a0\r\nPosibila problem\u0103 poate fi acum prev\u0103zut\u0103, deci \u0219i evitat\u0103!\r\n\u00a0\r\nMedicina nu st\u0103 \u00een loc, \u0219i \u00een lume recent a ap\u0103rut un test molecular cu posibilit\u0103\u021bi noi, care permite s\u0103 se deosebeasc\u0103 alergia \u201ereal\u0103\u201d la arahide de cea \u201efals\u0103\u201d, s\u0103 se prezic\u0103 riscul de reac\u021bii severe (dac\u0103 acestea se vor dezvolta sau nu), s\u0103 se aleag\u0103 varianta optim\u0103 de imunoterapie, \u0219i s\u0103 se r\u0103spund\u0103 la \u00eentrebarea cum influen\u021beaz\u0103 prelucrarea termic\u0103 asupra alergenicit\u0103\u021bii arahidelor. Dup\u0103 cum spun exper\u021bii, diagnosticarea molecular\u0103 este \u201eperforman\u021ba de top\u201d \u00een alergologia modern\u0103.\r\n\u00a0\r\nUnde se poate face analiza\r\n\r\nAst\u0103zi \u00een Republica Moldova diagnosticarea alergologic\u0103 molecular\u0103 pentru arahide este oferit\u0103 doar de laboratorul nostru ALFA diagnostica. Costul analizei este 700 de lei, dar informa\u021biile primite merit\u0103 ace\u0219ti bani. Mai multe despre acest test pute\u021bi afla pe site-ul oficial al laboratorului.","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/434\/1","url":"\/ro\/magazine\/alergia-la-arahidele-indragite-de-multi-434","url_full":"https:\/\/alfalab.md\/ro\/magazine\/alergia-la-arahidele-indragite-de-multi-434","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/alergia-la-arahidele-indragite-de-multi-434","show_startdate_d":"","show_enddate_d":"","date_d":"2018-09-24","show_startdate_text":"","show_enddate_text":"","date_text":"2018-09-24","date_day":"24","date_month":"Septembrie","date_published":"2021-11-16","date_modify":"2021-11-16","image_id":"182","image_ids":["182"],"image_url":"\/files\/getfile\/182\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/182\/","activegallery":[{"id":"233","parentclass":"magazine","idparentclass":"434","order":"1","idfile":"182","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/182\/","name":"36.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false},{"id":"433","status":"1","fixed":null,"show_startdate":null,"show_enddate":null,"date":"1537693200","views":null,"showonhome":"1","magazinetype":"2","name":"Este organismul dvs. pe cale s\u0103 fac\u0103 un tromb? Afla\u021bi acum.","author":"author blog meta","info":null,"title":"Este organismul dvs. pe cale s\u0103 fac\u0103 un tromb? Afla\u021bi acum.","urlsuffix":null,"description":"Oamenii nu vor s\u0103 fie bolnavi. Unii chiar depun eforturi serioase pentru aceasta. Dar situa\u021bii nepl\u0103cute cu s\u0103n\u0103tatea se \u00eent\u00e2mpl\u0103 oricum, \u0219i deseori brusc. Una din problemele neprev\u0103zute sunt trombozele, care au consecin\u021be nepl\u0103cute, \u0219i chiar tragice, cum ar fi atac de cord sau accident vascular cerebral. \r\n \r\nTrombozele nu apar, cum se spune, din senin. Este important contextul, predispozi\u021bia, \u201estarea de preg\u0103tire\u201d a organismului pentru tromboz\u0103, care \u00een \u0219tiin\u021b\u0103 se nume\u0219te trombofilie. \r\n \r\nComponenta principal\u0103 a trombofiliei este genetica. \u00cen prezent sunt bine studiate genele, muta\u021biile (sau mai corect, polimorfismele) din care creeaz\u0103 un fundal nefavorabil, care predispune la apari\u021bia trombozei. Cunosc\u00e2nd acest lucru, este posibil \u0219i chiar necesar de a lua m\u0103suri pentru a evita probleme serioase, sau, \u00een orice caz, pentru a explica motivul problemelor deja existente. \r\n \r\nSitua\u021bii diferite<\/strong> \r\n \r\nPe un om \u00eel a\u0219teapt\u0103 o interven\u021bie chirurgical\u0103, o femeie \u00eens\u0103rcinat\u0103 este pe cale s\u0103 nasc\u0103, o femeie t\u00e2n\u0103r\u0103 inten\u021bioneaz\u0103 s\u0103 ia contraceptive, o femeie are avorturi spontate, la o alt\u0103 femeie f\u0103tul moare la ultimele etape ale sarcinii, o a treie are varice pronun\u021bate pe picioare. Da, toate acestea sunt manifest\u0103ri ale trombozei. Dar cu acest lucru este posibil \u0219i chiar necesar de a lupta. \r\n \r\nLaboratorul nostru ALFA diagnostica a introdus mai multe teste genetice noi \u0219i, cel mai important, accesibile, care arat\u0103 dac\u0103 ave\u021bi sau nu predispozi\u021bie ereditar\u0103 spre formarea trombilor (trombofilie). \r\n \r\nTESTE GENETICE NOI:<\/span> \r\n \r\nAnaliza a 2 polimorfisme \u00een genele sistemului de hemostaz\u0103 : F2, F5<\/strong> \r\n<a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/G\/genotiparea-f2-f5-1829\">detalii\u00a0<\/span><\/a> \r\n \r\nAnaliza a 4 polimorfisme \u00een genele ciclului fola\u021bilor: MTR, MTRR, MTHFR<\/strong> \r\n<a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/G\/genotiparea-mtr-mtrr-mthfr-1823\">detalii\u00a0<\/span><\/a> \r\n \r\nAnaliza a 12 polimorfisme \u00een genele sistemului de hemostaz\u0103 \u0219i ciclul fola\u021bilor: F2, F5, F7, F13, PAI-1, ITGA2, ITGB3, FGB, MTR, MTRR, MTHFR<\/strong> \r\n<a href=\"https:\/\/alfalab.md\/ro\/analize-medicale\/G\/genotiparea-f2-f5-f7-f13-pai-1-itga2-itgb3-fgb-mtr-mtrr-mthfr-1822\">detalii\u00a0<\/span><\/a> \r\n \r\n \r\nTestele sunt informative, accesibile, \u0219i se efectueaz\u0103 \u00een termene cele mai scurte. Multe probleme din via\u021b\u0103 pot fi evitate, \u0219i trombozele nu sunt o excep\u021bie.<\/em> ","description_clear":"Oamenii nu vor s\u0103 fie bolnavi. Unii chiar depun eforturi serioase pentru aceasta. Dar situa\u021bii nepl\u0103cute cu s\u0103n\u0103tatea se \u00eent\u00e2mpl\u0103 oricum, \u0219i deseori brusc. Una din problemele neprev\u0103zute sunt trombozele, care au consecin\u021be nepl\u0103cute, \u0219i chiar tragice, cum ar fi atac de cord sau accident vascular cerebral.\r\n\r\nTrombozele nu apar, cum se spune, din senin. Este important contextul, predispozi\u021bia, \u201estarea de preg\u0103tire\u201d a organismului pentru tromboz\u0103, care \u00een \u0219tiin\u021b\u0103 se nume\u0219te trombofilie.\r\n\r\nComponenta principal\u0103 a trombofiliei este genetica. \u00cen prezent sunt bine studiate genele, muta\u021biile (sau mai corect, polimorfismele) din care creeaz\u0103 un fundal nefavorabil, care predispune la apari\u021bia trombozei. Cunosc\u00e2nd acest lucru, este posibil \u0219i chiar necesar de a lua m\u0103suri pentru a evita probleme serioase, sau, \u00een orice caz, pentru a explica motivul problemelor deja existente.\r\n\r\nSitua\u021bii diferite\r\n\r\nPe un om \u00eel a\u0219teapt\u0103 o interven\u021bie chirurgical\u0103, o femeie \u00eens\u0103rcinat\u0103 este pe cale s\u0103 nasc\u0103, o femeie t\u00e2n\u0103r\u0103 inten\u021bioneaz\u0103 s\u0103 ia contraceptive, o femeie are avorturi spontate, la o alt\u0103 femeie f\u0103tul moare la ultimele etape ale sarcinii, o a treie are varice pronun\u021bate pe picioare. Da, toate acestea sunt manifest\u0103ri ale trombozei. Dar cu acest lucru este posibil \u0219i chiar necesar de a lupta.\r\n\r\nLaboratorul nostru ALFA diagnostica a introdus mai multe teste genetice noi \u0219i, cel mai important, accesibile, care arat\u0103 dac\u0103 ave\u021bi sau nu predispozi\u021bie ereditar\u0103 spre formarea trombilor (trombofilie).\r\n\r\nTESTE GENETICE NOI:\r\n\r\nAnaliza a 2 polimorfisme \u00een genele sistemului de hemostaz\u0103 : F2, F5\r\ndetalii\u00a0\r\n\r\nAnaliza a 4 polimorfisme \u00een genele ciclului fola\u021bilor: MTR, MTRR, MTHFR\r\ndetalii\u00a0\r\n\r\nAnaliza a 12 polimorfisme \u00een genele sistemului de hemostaz\u0103 \u0219i ciclul fola\u021bilor: F2, F5, F7, F13, PAI-1, ITGA2, ITGB3, FGB, MTR, MTRR, MTHFR\r\ndetalii\u00a0\r\n\r\n\r\nTestele sunt informative, accesibile, \u0219i se efectueaz\u0103 \u00een termene cele mai scurte. Multe probleme din via\u021b\u0103 pot fi evitate, \u0219i trombozele nu sunt o excep\u021bie.","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_BLOG","url_preview":"\/ro\/magazine\/433\/1","url":"\/ro\/magazine\/este-organismul-dvs.-pe-cale-sa-faca-un-tromb-aflati-acum.-433","url_full":"https:\/\/alfalab.md\/ro\/magazine\/este-organismul-dvs.-pe-cale-sa-faca-un-tromb-aflati-acum.-433","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/este-organismul-dvs.-pe-cale-sa-faca-un-tromb-aflati-acum.-433","show_startdate_d":"","show_enddate_d":"","date_d":"2018-09-23","show_startdate_text":"","show_enddate_text":"","date_text":"2018-09-23","date_day":"23","date_month":"Septembrie","date_published":"2021-11-16","date_modify":"2021-11-16","image_id":"181","image_ids":["181"],"image_url":"\/files\/getfile\/181\/","image_fullurl":"https:\/\/alfalab.md\/files\/getfile\/181\/","activegallery":[{"id":"232","parentclass":"magazine","idparentclass":"433","order":"1","idfile":"181","isdefault":"0","status":"1","fullurl":"https:\/\/alfalab.md\/files\/getfile\/181\/","name":"35.jpg"}],"activeattachments":[],"activevideos":[],"videoobj":false}],"newsobjects":[{"id":"467","status":"1","fixed":null,"show_startdate":"1646344800","show_enddate":"1661979599","date":"1646388000","views":null,"showonhome":"0","magazinetype":"1","name":"Imunoterapia Alergen Specific\u0103","author":"author blog meta","info":null,"title":"Imunoterapia Alergen Specific\u0103","urlsuffix":null,"description":" \r\nStima\u021bi pacien\u021bi,\u00a0 \r\n \r\nPute\u021bi sc\u0103pa de alergiile la Ambrozie, Fungi, Acarienii prafului de cas\u0103 sau Polenul ierburilor!<\/strong><\/span> \r\n \r\nCentrul Interna\u021bional de Alergologie Molecular\u0103 ALFAllergy, care este o subdiviziune clinic\u0103 a ALFA diagnostica, \r\nanun\u021b\u0103 \u00eenceperea \u00eenscrierii pacien\u021bilor pentru imunoterapie alergen specific\u0103 \u2013 cea mai eficient\u0103 metod\u0103 de tratament \r\ncare ajut\u0103 la tratarea alergiilor la 90% dintre pacien\u021bi, care au urmat 3 sau mai multe cure de tratament.\u00a0 \r\n \r\nNu pierde\u021bi timpul, acum este momentul potrivit s\u0103 \u00eencepe\u021bi tratamentul!<\/strong> \r\nNum\u0103rul de medicamente este limitat. \r\n \r\nNum\u0103r de telefon (022) 901 100<\/span> \r\nalergie.md","description_clear":"Stima\u021bi pacien\u021bi,\u00a0\r\n\r\nPute\u021bi sc\u0103pa de alergiile la Ambrozie, Fungi, Acarienii prafului de cas\u0103 sau Polenul ierburilor!\r\n\r\nCentrul Interna\u021bional de Alergologie Molecular\u0103 ALFAllergy, care este o subdiviziune clinic\u0103 a ALFA diagnostica,\r\nanun\u021b\u0103 \u00eenceperea \u00eenscrierii pacien\u021bilor pentru imunoterapie alergen specific\u0103 \u2013 cea mai eficient\u0103 metod\u0103 de tratament\r\ncare ajut\u0103 la tratarea alergiilor la 90% dintre pacien\u021bi, care au urmat 3 sau mai multe cure de tratament.\u00a0\r\n\r\nNu pierde\u021bi timpul, acum este momentul potrivit s\u0103 \u00eencepe\u021bi tratamentul!\r\nNum\u0103rul de medicamente este limitat.\r\n\r\nNum\u0103r de telefon (022) 901 100\r\nalergie.md","keymeta":null,"descriptionmeta":null,"shortdescription":"","shortdescription_html":"","magazinetype_text":"magazinetype_NEWS","url_preview":"\/ro\/magazine\/467\/1","url":"\/ro\/magazine\/imunoterapia-alergen-specifica-467","url_full":"https:\/\/alfalab.md\/ro\/magazine\/imunoterapia-alergen-specifica-467","url_canonical":"https:\/\/alfalab.md\/ro\/magazine\/imunoterapia-alergen-specifica-467","show_startdate_d":"2022-03-04","show_enddate_d":"2022-08-31","date_d":"2022-03-04","show_startdate_text":"2022-03-04","show_enddate_text":"2022-08-31","date_text":"2022-03-04","date_day":"04","date_month":"Martie","date_published":"2022-03-04","date_modify":"2022-03-04","image_id":0,"image_ids":[],"image_url":"https:\/\/alfalab.md\/global\/_appl\/templates\/images\/DEFAULTIMG.jpg?","image_fullurl":"https:\/\/alfalab.md\/global\/_appl\/templates\/images\/DEFAULTIMG.jpg?","activegallery":[],"activeattachments":[],"activevideos":[],"videoobj":false}],"nextpagelabel":29,"nextpageurl":"\/blog\/magazine_page?&pag=1","seotematical":{"title":"Jurnal","keymeta":"keymeta magazine","descmeta":"descmeta magazine","canonical":"https:\/\/alfalab.md\/ro\/magazine"}}}